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SV40
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SV40Simian Virus 40, a monkey virus that contaminated the polio vaccine administered to 98 million Americans from 1955 to 1963, and has been associated with a number of rare human cancers. One controversial theory links SV40 to mesothelioma.
RELATED TERMS--------------------------------------
Virus
Ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein.
Polio
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus. Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse fasciculation and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses.
Vaccine
A preparation, often of living weakened microorganisms, that is introduced into the body to produce immunity to a specific disease by causing the formation of antibodies.
SV40
Simian Virus 40, a monkey virus that contaminated the polio vaccine administered to 98 million Americans from 1955 to 1963, and has been associated with a number of rare human cancers. One controversial theory links SV40 to mesothelioma.
Mesothelioma
Malignant spreading tumour of the mesothelium of the pleura, pericardium, or peritoneum, arising as a result of the presence of asbestos fibres. It is diagnostic of exposure to asbestos.
SIMILAR TERMS--------------------------------------
PREVIOUS AND NEXT TERMS--------------------------------------
Soman
An extremely potent cholinesterase inhibitor, similar to sarin and tabun.
Sterile abscess
An abscess whose contents are not caused by pyogenic bacteria.
Superantigen
An antigen that interacts with the T cell receptor in a domain outside of the antigen recognition site. This type of interaction induces the activation of larger numbers of T cells compared to antigens that are presented in the antigen recognition site.
Screening
Testing for disease in people without symptoms.
Silicosis
A form of chronic lung disease which develops after prolonged exposure to silica (quartz) dust.
SV40
Safety
relative freedom from harm; in clinical trials, this refers to an absence of harmful side effects resulting from use of the product and may be assessed by laboratory testing of biological samples, special tests and procedures, psychiatric evaluation, and/or physical examination of subjects.
Safety and tolerability
The safety of a medical product concerns the medical risk to the subject, usually assessed in a clinical trial by laboratory tests (including clinical chemistry and haematology), vital signs, clinical adverse events (diseases, signs and symptoms), and other special safety, tests (for example, ECGs opthamology). The tolerability of the medical product represents the degree to which overt adverse effects can be tolerated by the subject
Serious adverse drug reaction (SADR)
A serious adverse event (SAE) which is possibly an adverse drug reaction (ADR)
Serious adverse event (SAE)
Any untoward medical occurrence that results in death, is life threatening, requires inpatient hospitalisation or prolongation of existing hospitalisation, results in persistent or significant disability/incapacity, or is a congenital anomaly/birth defect. See adverse event (AE)
Single-blind study
One in which subjects do not know whether they are receiving the active drug or a placebo, but the investigator does know
RELATED TERMS--------------------------------------
Virus
Ultramicroscopic infectious agent that replicates itself only within cells of living hosts; many are pathogenic; a piece of nucleic acid (DNA or RNA) wrapped in a thin coat of protein.
Polio
An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus. Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse fasciculation and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses.
Vaccine
A preparation, often of living weakened microorganisms, that is introduced into the body to produce immunity to a specific disease by causing the formation of antibodies.
SV40
Simian Virus 40, a monkey virus that contaminated the polio vaccine administered to 98 million Americans from 1955 to 1963, and has been associated with a number of rare human cancers. One controversial theory links SV40 to mesothelioma.
Mesothelioma
Malignant spreading tumour of the mesothelium of the pleura, pericardium, or peritoneum, arising as a result of the presence of asbestos fibres. It is diagnostic of exposure to asbestos.
SIMILAR TERMS--------------------------------------
PREVIOUS AND NEXT TERMS--------------------------------------
Soman
An extremely potent cholinesterase inhibitor, similar to sarin and tabun.
Sterile abscess
An abscess whose contents are not caused by pyogenic bacteria.
Superantigen
An antigen that interacts with the T cell receptor in a domain outside of the antigen recognition site. This type of interaction induces the activation of larger numbers of T cells compared to antigens that are presented in the antigen recognition site.
Screening
Testing for disease in people without symptoms.
Silicosis
A form of chronic lung disease which develops after prolonged exposure to silica (quartz) dust.
SV40
Safety
relative freedom from harm; in clinical trials, this refers to an absence of harmful side effects resulting from use of the product and may be assessed by laboratory testing of biological samples, special tests and procedures, psychiatric evaluation, and/or physical examination of subjects.
Safety and tolerability
The safety of a medical product concerns the medical risk to the subject, usually assessed in a clinical trial by laboratory tests (including clinical chemistry and haematology), vital signs, clinical adverse events (diseases, signs and symptoms), and other special safety, tests (for example, ECGs opthamology). The tolerability of the medical product represents the degree to which overt adverse effects can be tolerated by the subject
Serious adverse drug reaction (SADR)
A serious adverse event (SAE) which is possibly an adverse drug reaction (ADR)
Serious adverse event (SAE)
Any untoward medical occurrence that results in death, is life threatening, requires inpatient hospitalisation or prolongation of existing hospitalisation, results in persistent or significant disability/incapacity, or is a congenital anomaly/birth defect. See adverse event (AE)
Single-blind study
One in which subjects do not know whether they are receiving the active drug or a placebo, but the investigator does know
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This dictionary contains 19186 terms.
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