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Osteomalacia
Osteomalacia A disease of adults that is characterized by softening of the bones due to loss of bone mineral. Osteomalacia is characteristic of vitamin D deficiency in adults, while children with vitamin D deficiency suffer from rickets. RELATED TERMS-------------------------------------- Disease Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus. Bone Bone refers either to a hardened connective tissue or to one of the individual structures, or organs, into which it is formed, found in many animals. Bones support body structures, protect internal organs, and (in conjunction with muscles) facilitate movement; are also involved with cell formation, calcium metabolism, and mineral storage. The bones of an animal are, collectively, known as the skeleton. Mineral An inorganic compound needed by the body for good health, proper metabolic functioning, and disease prevention. Examples are calcium, magnesium, and iron. Osteomalacia A disease of adults that is characterized by softening of the bones due to loss of bone mineral. Osteomalacia is characteristic of vitamin D deficiency in adults, while children with vitamin D deficiency suffer from rickets. Vitamin Any of many organic substances that are vital in small amounts to the normal functioning of the body. Vitamins are found in food, produced by the body, and manufactured synthetically; along with minerals, they are known as micronutrients. Rickets A disorder of childhood characterised by defective bone and mineralisation, where characteristic lower limb bowing or bending occurs. Other outward signs of rickets can be the so-called rachitic rosary on the ribs, and thickened wrists, as well as bossing of the forehead. SIMILAR TERMS-------------------------------------- Osteitis condensans ilii Sclerosis at the sacral side of the sacroiliac joint. Unknown aetiology. May be confused with sacroiliitis. Osteitis deformans Paget's disease of bone. Osteitis fibrosa cystica Bone disease which occurs in hyperparathyroidism. Excess fibrous tissue and osteoclasts are found in lesions which may become cystic ('Brown tumours'). Osteoarthritis Degenerative disorder of joints, most often from disease in the spine and in the weight bearing joints (knees and hips). Normally seen with aging, but can occur prematurely due to various reasons, for instance after an injury to a joint. Also known as degenerative joint disease, it can cause joint pain, loss of function, reduced joint motion, and deformity. Osteoarthrosis Synonymous with 'osteoarthritis'. Osteoblast A type of bone cell characterized by its mobility and by its ability to produce bone matrix. Osteoblastic Osteoblastic refers to something pertaining to or composed of osteoblasts. Osteoblastoma Usually benign but occasionally malignant and metastasising tumour which occurs most commonly in the spine. Osteocalcin A protein found in young osteoblasts. (GLA protein, BGP) Serum level reflects rate of bone turnover. Osteochondritis dissecans A form of osteonecrosis in which a segment of bone and articular cartilage become demarcated and separate from the surrounding bone. Most commonly occurs in the knee. Osteochondritis Dissecans Osteochondritis Dissecans refers to a bone degeneration inside of a joint, causing small pieces of bone and cartilage to become detached. Osteochondroma A benign cartilage-tipped exostosis. Osteoclast Bone-resorbing cell. Osteocyte A type of bone cell characterized by its immobile location within a lacunus and by a reduced ability to produce bone matrix. Osteogenesis imperfecta An inherited disorder of collagen which takes several forms. Premature osteoarthritis, blue sclerae, hypermobility and bone fragility may be features of the condition. Osteogenic sarcoma A malignant bone tumour which may occasionally arise in bone affected by Paget's disease. Osteoid Non-mineralised bone matrix. Osteoid osteoma A benign, osteoid-forming tumour. May be very painful, especially at night. Osteolite Osteolite is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): technetium tc-99m medronate kit. Osteoma Tumor of bone. Osteomyelitis Inflammation of bone. Osteonecrosis See 'Aseptic necrosis'. Osteopathic Medical Center The Osteopathic Medical Center is a hospital in Fort Worth, Texas, United States. Osteopathic Medical Center of Texas Osteopathic Medical Center of Texas is a hospital in Fort Worth, Texas (USA). Osteopathic Medical Center-Philadelphia The Osteopathic Medical Center-Philadelphia is a hospital in Philadelphia, Pennsylvania, United States. Osteopathy A system of therapy emphasizing primary medical care and the importance of body mechanics and manipulation to correct abnormalities. Osteopenia 'Thin' bone due to osteomalacia or osteoporosis. Osteophyte Bony outgrowth seen at joint margin in osteoarthritis. Osteoporosis Break-down or disintegration of bone, resulting in diminished and porous bone mass. Osteoporosis can result from cancer (including breast cancer) that has spread to the bones), some cancer therapies, and estrogen deficiency (estrogen is an important participant in maintaining bone). Osteoporosis can cause pain, deformity (especially of the spine), pathologic fractures (fractures caused by weakened bone), or traumatic fractures (for example, wrist or hip fracture from a fall). Osteopuncture Form of acupuncture named by Ronald M. Lawrence, M.D. In osteopuncture, the needle penetrates the periosteum (the membrane that covers bones) and is usually electrified. The acupuncture points of osteopuncture do not correlate with "meridian points." Osteosarcoma Osteosarcoma is the most common primary malignant bone tumour, excluding myeloma and lymphoma. There is a predilection for the metaphyseal region of tubular long bones. 50% of cases occur around the knee. It is a cancer that usually affects the large bones of the arm or leg. It occurs most commonly in young people and affects more males than females. Also called osteogenic sarcoma. Osteoscan Osteoscan is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): technetium tc-99m etidronate kit. Osteotomy Operation to produce realignment of articular surfaces of a joint so as to exploit remaining undamaged cartilage. PREVIOUS AND NEXT TERMS-------------------------------------- Osteosarcoma Osteosarcoma is the most common primary malignant bone tumour, excluding myeloma and lymphoma. There is a predilection for the metaphyseal region of tubular long bones. 50% of cases occur around the knee. It is a cancer that usually affects the large bones of the arm or leg. It occurs most commonly in young people and affects more males than females. Also called osteogenic sarcoma. Ovaries The paired female sex glands in the pelvis, located one on each side of the uterus. The ovaries produce eggs and hormones including estrogen, progesterone, and androgens. Osteoarthritis Degenerative disorder of joints, most often from disease in the spine and in the weight bearing joints (knees and hips). Normally seen with aging, but can occur prematurely due to various reasons, for instance after an injury to a joint. Also known as degenerative joint disease, it can cause joint pain, loss of function, reduced joint motion, and deformity. Obesity Abnormal body weight, usually defined as more than 20 percent above average for age, height and bone structure. Obsessive-Compulsive Disorder A type of anxiety disorder marked by the persistent intrusion of unwanted and uncontrollable thoughts. Commonly, patients who suffer from obsessions also suffer from compulsions - repeated, senseless rituals victims go through in an attempt to reduce their anxiety. While compulsive behavior is almost always preceded by obsessive thoughts, some people have obsessive thoughts but do not ritualize. Osteomalacia Osteoblast A type of bone cell characterized by its mobility and by its ability to produce bone matrix. Osteocyte A type of bone cell characterized by its immobile location within a lacunus and by a reduced ability to produce bone matrix. OI Osteogenesis Imperfecta. A genetic disorder that is also characterized by easily fractured bones. Oxytocin A hormone secreted by the pituitary gland which plays a role in childbirth. We thank you for using the Medical Glossary to search for Osteomalacia. If you have a better definition for Osteomalacia than the one presented here, please let us know by making use of the suggest a term option. This definition of Osteomalacia may be disputed by other professionals. Our attempt is to provide easy definitions on Osteomalacia and any other medical topic for the public at large.
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