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Optic nerve hypoplasia
Optic nerve hypoplasia small and underdeveloped optic nerve. Optic nerve hypoplasia is one of the leading causes of vision loss and blindness in infants and children. Optic nerve hypoplasia occurs in the early stages of fetal development, when the eyes are forming. The optic nerve never fully develops or, once developed, dies-off and reduces in size for unknown reasons. Recent evidence suggests that ganglion cell axons, that make-up the optic nerve, are not able to grow through the optic nerve head because certain chemical messengers are not present for directional growth from the eye to the brain. Optic nerve hypoplasia is variable, and can result in only minor vision problems to complete blindness. Usually, if the infant has nystagmus the optic nerve hypoplasia is more severe and vision is very much reduced. If the infant does not have nystagmus, the likelihood for significant vision loss in less. All infants with optic nerve hypoplasia should have a CT scan or MRI to look for midline brain defects that can result in body growth problems. If the infant does not have nystagmus, the chance of midline brain defects is small. If the infant has nystagmus, the chance of midline defects is greater. Some infants have optic nerve hypoplasia in one eye only. If only in one eye, the chance of midline defects is very small and the doctor may chose not to do a CT scan or MRI, depending on other factors. There is no treatment or cure for optic nerve hypoplasia. RELATED TERMS-------------------------------------- Nerve Tissue that conveys sensation, temperature, position information to the brain. Hypoplasia Underdevelopment of a tissue or organ usually due to a decrease in the number of cells. Vision The sense of sight. Blindness Legal blindness is defined as: 1) visual acuity of 20/200 (only being able to see the big E on the eye chart) or less in the best eye even with the eyes corrected by glasses or contact lenses; or, 2) The peripheral visual field is reduced to 20 degrees of visual angle or less. Twenty degrees of visual angle is about the size of a one foot ruler held at arms length. Fetal Having to do with the fetus. Development The process of growth and differentiation. Ganglion A cluster of nerve cells. Cell Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid. Brain "That part of the central nervous system that is located within the cranium (skull). The brain functions as the primary receiver, organizer and distributor of information for the body. It has two (right and left) halves called ""hemispheres."" " Infant A child under a year of age. Nystagmus Nystagmus is a rhythmic, repetitive, oscillatory eye movement. It may occur as a result of vestibular problems, as a result of visual problems, or as a result of certain brain stem or cerebellar abnormalities. Vestibular Nystagmus is characterized by a slow migration of the eyes in the wrong direction, followed by a sudden jerking back response. Eye The organ of sight. The eye has a number of components. These components include but are not limited to the cornea, iris, pupil, lens, retina, macula, optic nerve, choroid and vitreous. Doctor 1. One whose occupation is to treat diseases, particularly a physician, dentist, or veterinarian with an appropriate license. 2. A teacher (particularly at a college or university), a scholar, or one who holds a postgraduate degree (especially a Ph.D. degree). 3. A shaman. MRI Magnetic Resonance Imaging is a diagnostic procedure that uses a combination of large magnets, radiofrequencies, and a computer to produce detailed images of organs and structures within the body. Cure 1. To heal, to make well, to restore to good health. Cures are easy to claim and, all too often, difficult to confirm. 2. A time without recurrence of a disease so that the risk of recurrence is small, as in the 5-year cure rate for malignant melanoma. 3. Particularly in the past, a course of treatment. SIMILAR TERMS-------------------------------------- Optic atrophy A disease of the optic nerve in which the nerve fibers carrying the electrical impulses from the eye to the brain start to die off. In such cases the optic nerve has a pale or whitish appearance compared to the normal pink color. Optic atrophy is associated with poor reading vision and often the cause of legal blindness. May be associated with a serious medical condition and requires further medical examination to determine the cause of the atrophy. Not reversible. Optic chiasm Location where the optic nerve axons from the two retinae join and are reorganized into two separate groups (the optic tracts) that encode information about the right and left visual fields. Optic disc The visible part of the optic nerve inside the eye. The axons of the ganglion cells of the inner retina make-up the optic nerve. Optic disk Where the ganglion cell axon fibers leave the retina. Contains no photoreceptors and therefore creates a blind spot in the visual field. Optic nerve Sensory nerve that transmits impulses from the retina to the brain that become what we know as vision. Optic nerves Myelinated axons from the optic disk of each eye which join at the optic chiasm. Optic neuritis Optic neuritis An inflammation of the optic nerve usually with some loss of sight (may be temporary). It may signify a more serious neurological condition. A leading cause of optic neuritis is multiple sclerosis (MS). Optic radiations Projections from LGN to primary visual cortex (V1). Optic tectum Structure in the mid-brain of cold-blooded vertebrate that receives input from the optic nerve (homologous to the superior colliculi). Optic tract Retinal fibers leaving the optic chiasm separated by visual hemi-field (i.e. not by eye). Projects to three areas, the pretectum, the superior colliculus and the LGN. Optical Having to do with vision. Optical power (of a lens) Measure of how strongly a lens bends incoming rays. Measured in diopters and equal to the reciprocal of focal length. Human eye has an optical power of about 58.8 diopters. Optician A technician who fits a person for glasses. He/she does not test for glasses. Some opticians also fit contact lenses. Opticrom Opticrom is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): cromolyn sodium. Optimark Optimark is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): gadoversetamide. Optimark in plastic container Optimark in plastic container is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): gadoversetamide. Optimine Optimine is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): azatadine maleate. Optipranolol Optipranolol is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): metipranolol hydrochloride. Optiray 160 Optiray 160 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): ioversol. Optiray 240 Optiray 240 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): ioversol. Optiray 300 Optiray 300 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): ioversol. Optiray 320 Optiray 320 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): ioversol. Optiray 350 Optiray 350 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): ioversol. Optison Optison is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): albumin human. Optivar Optivar is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): azelastine hydrochloride. PREVIOUS AND NEXT TERMS-------------------------------------- Oculus Uterque OU; Both eyes. Ophthalmologist A physician (MD) who specializes in the diagnosis and treatment of eye problems and diseases. The ophthalmologist works with the use of glasses, contact lenses, eye medication and surgery. Optic atrophy A disease of the optic nerve in which the nerve fibers carrying the electrical impulses from the eye to the brain start to die off. In such cases the optic nerve has a pale or whitish appearance compared to the normal pink color. Optic atrophy is associated with poor reading vision and often the cause of legal blindness. May be associated with a serious medical condition and requires further medical examination to determine the cause of the atrophy. Not reversible. Optic disc The visible part of the optic nerve inside the eye. The axons of the ganglion cells of the inner retina make-up the optic nerve. Optician A technician who fits a person for glasses. He/she does not test for glasses. Some opticians also fit contact lenses. Optic nerve hypoplasia Optic neuritis Optic neuritis An inflammation of the optic nerve usually with some loss of sight (may be temporary). It may signify a more serious neurological condition. A leading cause of optic neuritis is multiple sclerosis (MS). Optometrist OD; A licensed non-physician educated to detect eye problems with special emphasis on correcting refractive errors. Depending on training, an Optometrist may use diagnostic and therapeutic medicines. An Optometrist does not perform surgery Ovarian cancer Tumors or cancer of the ovary. Opsonin A substance, usually antibody or complement component, which coats a particle such as a bacterium and enhances phagocytosis by phagocytic cells. We thank you for using the Medical Glossary to search for Optic nerve hypoplasia. If you have a better definition for Optic nerve hypoplasia than the one presented here, please let us know by making use of the suggest a term option. This definition of Optic nerve hypoplasia may be disputed by other professionals. Our attempt is to provide easy definitions on Optic nerve hypoplasia and any other medical topic for the public at large.
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