Medical Glossary

This glossary contains:
19186
medical terms

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Internal image

A spatial configuration of the combining site of an anti-idiotype antibody which resembles the epitope to which the idiotype is directed.

RELATED TERMS
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Antibody
An infection-fighting protein molecule in blood or secretory fluids that tags, neutralizes, and helps destroy pathogenic microorganisms (eg, bacteria, viruses) or toxins. Antibodies, known generally as immunoglobulins, are made and secreted by B-lymphocytes in response to stimulation by antigens. Each specific antibody binds only to the specific antigen that stimulated its production.

Epitope
An alternative term for antigenic determinant.

Idiotype
The combined antigenic determinants (idiotopes) found on antibodies of an individual that are directed at a particular antigen; such antigenic determinants are found only in the variable region.



SIMILAR TERMS
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Integrated Health Service
The Integrated Health Service is a hospital in Erie, Pennsylvania, United States.

Integrated Health Services
The Integrated Health Services is a hospital in Canonsburg, Pennsylvania, United States.

Integration
The useful organization and incorporation of both new and old data, experience, and emotional capacities into the personality. Also refers to the organization and amalgamation of functions at various levels of psychosexual development.

Integrilin
Integrilin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): eptifibatide.

Integrins
Family of glycoproteins involved in connecting the cytoskeleton to the extracellular environment.

INTEGRIS Baptist Regional Health Center
INTEGRIS Baptist Regional Health Center is a hospital in Oklahoma City, Oklahoma (USA).

INTEGRIS Bass Baptist Health Center
INTEGRIS Bass Baptist Health Center is a hospital in Enid, Oklahoma (USA).

INTEGRIS Health
INTEGRIS Health is a hospital in Oklahoma City, Oklahoma (USA).

Integument
Skin.

Intellectualization
A mental mechanism in which the person engages in excessive abstract thinking to avoid confrontation with conflicts or disturbing feelings.

Intensive care unit
A department of a hospital where an individual can be constantly and closely monitored.

Intensive Care Unit (ICU)
A special nursing area devoted to providing continuous and immediate care to seriously ill patients.

Intensive Management
A form of treatment for insulin-dependent diabetes in which the main objective is to keep blood glucose (sugar) levels as close to the normal range as possible. The treatment consists of three or more insulin injections a day or use of an insulin pump; four or more blood glucose tests a day; adjustment of insulin, food intake, and activity levels based on blood glucose test results; dietary counseling; and management by a diabetes team.

Intention-to-treat principle
The principle that asserts that the effect of a treatment policy can be best assessed by evaluating, on the basis of the intention to treat a subject (that is, the planned treatment regimen) rather than the actual treatment given. It has the consequence that subjects allocated to a treatment group should be followed up, assessed and analysed as members of that group irrespective of their compliance to the planned course of treatment.

Interaction (qualitative and quantitative)
The situation in which a treatment contrast (for example, difference between investigational product and control) is dependent on another factor (for example, centre). A quantitative interaction refers to the case where the magnitude of the contrast differs at the different levels of the factor, whereas for a qualitative interaction the direction of the contrast differs for at least one level of the factor.

Interaxillary
In the armpit, or between the upper arm and lateral chest.

Intercalated zones
Areas of cells falling between the parvocellular and magnocellular layers.

Intercellular
Between two cells.

Intercourse
Connection or interaction between people. In sexual intercourse, the connection is usually defined as being between two people. It is erroneously restricted to putting the penis into the vagina (or anus) or the vagina (or anus) onto the penis (penovaginal or penoanal intercourse, respectively). The entire sexual interaction between the partners constitutes sexual intercourse. 2. Connection or interaction between people. In sexual intercourse, the connection is usually defined as being between two people. It is erroneously defined as putting the penis into the vagina (penovaginal intercourse), for the entire sexual interaction between the partners constitutes sexual intercourse.

Interfemoral
Between the thighs.

Interferon
A group of proteins having antiviral activity and capable of enhancing and modifying the immune response.

Interictal
Pertaining to the interval between epileptic seizures and seizure-like attacks.

Interim analysis
Any analysis intended to compare treatment arms with respect to efficacy or safety at any time prior to the formal completion of a trial, usually only completed in blinded trials, for a DMC review.

Interim clinical trial/study report
A report of intermediate results and their evaluation based on analyses performed during the course of a trial, usually prepared for review by DMC.

Interleukins
A family of cytokines produced by leucocytes

Intermammary
Between the breasts.

Intermittent Claudication
Pain in the muscles of the leg that occurs off and on, usually while walking or exercising, and results in lameness (claudication). The pain results from a narrowing of the blood vessels feeding the muscle. Drugs are available to treat this condition.

Intermountain Healthcare
Intermountain Healthcare is a hospital in Salt Lake City, Utah (USA).

Intern
A medical doctor who has completed medical school and is in the first year of additional training.

Internal consistency
A property of data that does not contradict itself.

Internal Medicine
A broad-based medical field in which physicians rely on their knowledge of major organs to diagnose and treat patients. Internists treat a variety of afflictions, from colds and heart problems to infectious diseases. Internists often serve as a patient's primary doctor, coordinating all that person's health care

Internal medicine doctor
A medical doctor who specializes in Internal medicine.

Internist
An advanced student or graduate in medicine gaining supervised practical experience.

Interocclusal
Space between upper and lower teeth.

Interocular motion display
A motion display in which the motion stimulus in each eye of the observer is ambiguous, yet perception of coherent motion is possible if the subject combines motion information from both the eyes.

Interproximal
Surfaces of adjoining teeth

Interrater reliability
The property of yielding equivalent results when used by different raters on different occasions.

Intersex condition
A condition in which an individual shows intermingling, in various degrees, of the characteristics of each sex, including physical form, reproductive organs, and sexual behavior.

Intersexuality
An alternative term for hermaphroditism. In past usage, a genetic etiology was sometimes assumed for intersexuality, and a hormonal etiology for hermaphroditism, but the distinction is now known to be untenable.

Interstitial radiation therapy
The implantation of radioactive seeds directly into a tumor.

Interstitial space
The space between the endothelial cells and target cells, such as the liver or the smooth muscle cells that line the vascular bed.

Intervention
In healthcare, any attempt (particularly one that is professional), or mode of attempting, to modify a medical situation.

Intestinal flora
The bacteria, yeasts, and fungi that grow normally in the intestines.

Intestinal mucosa
The surface lining of the intestines where the cells absorb nutrients.

Intestine
The tube involved in digestion and extending from the stomach to the anus. Consists of the small intestine and the large intestine.

Intestines
See large intestine and small intestine. Also called gut.



PREVIOUS AND NEXT TERMS
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Immune modulators
Substances that control the expression of the immune response.

Immune response (Ir) gene
A gene controlling an immune response to a particular antigen; most genes of this type are in the MHC (major histocompatibility complex), and the term is rarely used to describe other types of Ir genes outside the MHC.

Immunogen
A substance capable of inducing an immune response (as well as reacting with the products of an immune response). Compare with antigen.

Immunoglobulin (Ig)
A general term for all antibody molecules. Each Ig unit is made up of two heavy chains and two light chains and has two antigen- binding sites.

Interferon
A group of proteins having antiviral activity and capable of enhancing and modifying the immune response.

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Intron
A segment of DNA that does not code for protein; the intervening sequence of nucleotides between coding sequences or exons.

Isograft
A tissue transplanted between two genetically identical individuals.

Isohemagglutinins
Antibodies to major red blood cell antigens present normally as a result of inapparent immunization by cross-reactive antigens in bacteria, food, etc.

Isotypes
Classes of antibody that differ in the constant region of their heavy chain (Fc portion); distinguishable also on the basis of reaction with antisera raised in another species. These differences also result in different biological activities of the antibodies.

Isotype switch
The shift of a B cell or its progeny from the secretion of antibody of one isotype or class of antibody with the same V regions but a different heavy- chain constant region and, hence, a different isotype (class switch).

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This dictionary contains 19186 terms.







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