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Intermittent Claudication
Intermittent ClaudicationPain in the muscles of the leg that occurs off and on, usually while walking or exercising, and results in lameness (claudication). The pain results from a narrowing of the blood vessels feeding the muscle. Drugs are available to treat this condition. RELATED TERMS-------------------------------------- Pain An unpleasant sensory or emotional experience primarily associated with tissue damage, or described in terms of tissue damage, or both. Blood The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues. Muscle Tissue made up of bundles of long, slender cells that contract when stimulated. Condition The term "condition" has a number of biomedical meanings including the following: 1.An unhealthy state, such as in "this is a progressive condition." 2.A state of fitness, such as "getting into condition." 3.Something that is essential to the occurrence of something else; essentially a "precondition." 4.As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning. SIMILAR TERMS-------------------------------------- Integrated Health Service The Integrated Health Service is a hospital in Erie, Pennsylvania, United States. Integrated Health Services The Integrated Health Services is a hospital in Canonsburg, Pennsylvania, United States. Integration The useful organization and incorporation of both new and old data, experience, and emotional capacities into the personality. Also refers to the organization and amalgamation of functions at various levels of psychosexual development. Integrilin Integrilin is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): eptifibatide. Integrins Family of glycoproteins involved in connecting the cytoskeleton to the extracellular environment. INTEGRIS Baptist Regional Health Center INTEGRIS Baptist Regional Health Center is a hospital in Oklahoma City, Oklahoma (USA). INTEGRIS Bass Baptist Health Center INTEGRIS Bass Baptist Health Center is a hospital in Enid, Oklahoma (USA). INTEGRIS Health INTEGRIS Health is a hospital in Oklahoma City, Oklahoma (USA). Integument Skin. Intellectualization A mental mechanism in which the person engages in excessive abstract thinking to avoid confrontation with conflicts or disturbing feelings. Intensive care unit A department of a hospital where an individual can be constantly and closely monitored. Intensive Care Unit (ICU) A special nursing area devoted to providing continuous and immediate care to seriously ill patients. Intensive Management A form of treatment for insulin-dependent diabetes in which the main objective is to keep blood glucose (sugar) levels as close to the normal range as possible. The treatment consists of three or more insulin injections a day or use of an insulin pump; four or more blood glucose tests a day; adjustment of insulin, food intake, and activity levels based on blood glucose test results; dietary counseling; and management by a diabetes team. Intention-to-treat principle The principle that asserts that the effect of a treatment policy can be best assessed by evaluating, on the basis of the intention to treat a subject (that is, the planned treatment regimen) rather than the actual treatment given. It has the consequence that subjects allocated to a treatment group should be followed up, assessed and analysed as members of that group irrespective of their compliance to the planned course of treatment. Interaction (qualitative and quantitative) The situation in which a treatment contrast (for example, difference between investigational product and control) is dependent on another factor (for example, centre). A quantitative interaction refers to the case where the magnitude of the contrast differs at the different levels of the factor, whereas for a qualitative interaction the direction of the contrast differs for at least one level of the factor. Interaxillary In the armpit, or between the upper arm and lateral chest. Intercalated zones Areas of cells falling between the parvocellular and magnocellular layers. Intercellular Between two cells. Intercourse Connection or interaction between people. In sexual intercourse, the connection is usually defined as being between two people. It is erroneously restricted to putting the penis into the vagina (or anus) or the vagina (or anus) onto the penis (penovaginal or penoanal intercourse, respectively). The entire sexual interaction between the partners constitutes sexual intercourse. 2. Connection or interaction between people. In sexual intercourse, the connection is usually defined as being between two people. It is erroneously defined as putting the penis into the vagina (penovaginal intercourse), for the entire sexual interaction between the partners constitutes sexual intercourse. Interfemoral Between the thighs. Interferon A group of proteins having antiviral activity and capable of enhancing and modifying the immune response. Interictal Pertaining to the interval between epileptic seizures and seizure-like attacks. Interim analysis Any analysis intended to compare treatment arms with respect to efficacy or safety at any time prior to the formal completion of a trial, usually only completed in blinded trials, for a DMC review. Interim clinical trial/study report A report of intermediate results and their evaluation based on analyses performed during the course of a trial, usually prepared for review by DMC. Interleukins A family of cytokines produced by leucocytes Intermammary Between the breasts. Intermountain Healthcare Intermountain Healthcare is a hospital in Salt Lake City, Utah (USA). Intern A medical doctor who has completed medical school and is in the first year of additional training. Internal consistency A property of data that does not contradict itself. Internal image A spatial configuration of the combining site of an anti-idiotype antibody which resembles the epitope to which the idiotype is directed. Internal Medicine A broad-based medical field in which physicians rely on their knowledge of major organs to diagnose and treat patients. Internists treat a variety of afflictions, from colds and heart problems to infectious diseases. Internists often serve as a patient's primary doctor, coordinating all that person's health care Internal medicine doctor A medical doctor who specializes in Internal medicine. Internist An advanced student or graduate in medicine gaining supervised practical experience. Interocclusal Space between upper and lower teeth. Interocular motion display A motion display in which the motion stimulus in each eye of the observer is ambiguous, yet perception of coherent motion is possible if the subject combines motion information from both the eyes. Interproximal Surfaces of adjoining teeth Interrater reliability The property of yielding equivalent results when used by different raters on different occasions. Intersex condition A condition in which an individual shows intermingling, in various degrees, of the characteristics of each sex, including physical form, reproductive organs, and sexual behavior. Intersexuality An alternative term for hermaphroditism. In past usage, a genetic etiology was sometimes assumed for intersexuality, and a hormonal etiology for hermaphroditism, but the distinction is now known to be untenable. Interstitial radiation therapy The implantation of radioactive seeds directly into a tumor. Interstitial space The space between the endothelial cells and target cells, such as the liver or the smooth muscle cells that line the vascular bed. Intervention In healthcare, any attempt (particularly one that is professional), or mode of attempting, to modify a medical situation. Intestinal flora The bacteria, yeasts, and fungi that grow normally in the intestines. Intestinal mucosa The surface lining of the intestines where the cells absorb nutrients. Intestine The tube involved in digestion and extending from the stomach to the anus. Consists of the small intestine and the large intestine. Intestines See large intestine and small intestine. Also called gut. PREVIOUS AND NEXT TERMS-------------------------------------- Insulin Reaction Too low a level of glucose (sugar) in the blood; also called hypoglycemia. This occurs when a person with diabetes has injected too much insulin, eaten too little food, or exercised without extra food. The person may feel hungry, nauseated, weak, nervous, shaky, confused, and sweaty. Taking small amounts of sugar, sweet juice, or food with sugar will usually help the person feel better within 10-15 minutes. Insulin Receptors Areas on the outer part of a cell that allow the cell to join or bind with insulin that is in the blood. When the cell and insulin bind together, the cell can take glucose (sugar) from the blood and use it for energy. Insulin Sensitizer Any of several diabetes medications that reduce insulin resistance. Examples include metformin (Glucophage) and the thiazolidinediones (or "glitazones") rosiglitazone (Avandia) and pioglitazone (Actos). Insulin Shock A term no longer used. See Hypoglycemia; insulin reaction. Insulinoma A tumor of the beta cells in areas of the pancreas called the islets of Langerhans. Although not usually cancerous, such tumors may cause the body to make extra insulin and may lead to a blood glucose (sugar) level that is too low. Intermittent Claudication Intensive Management A form of treatment for insulin-dependent diabetes in which the main objective is to keep blood glucose (sugar) levels as close to the normal range as possible. The treatment consists of three or more insulin injections a day or use of an insulin pump; four or more blood glucose tests a day; adjustment of insulin, food intake, and activity levels based on blood glucose test results; dietary counseling; and management by a diabetes team. Intramuscular Injection Putting a fluid into a muscle with a needle and syringe. Intravenous Injection Putting a fluid into a vein with a needle and syringe. IAA antiinsulin GAD65 anti glutamic acid decarboxylase |ICA512 a specific islet cell antibody |EMA antiendomyseal antibodies (a test for celiac synmdrome, another autoimmune disorder occurring in 5% of new-onset Type 1 diabetes) Islet Cell Transplantation Moving the beta (islet) cells from a donor pancreas and putting them into a person whose pancreas has stopped producing insulin. The beta cells make the insulin that the body needs to use glucose (sugar) for energy. Although transplanting islet cells may one day help people with diabetes, the procedure is still in the research stage. Transplantation of the pancreas itself is surgically feasible, and is sometimes advised for some patients. |See also: Pancreas Transplant. We thank you for using the Medical Glossary to search for Intermittent Claudication. If you have a better definition for Intermittent Claudication than the one presented here, please let us know by making use of the suggest a term option. This definition of Intermittent Claudication may be disputed by other professionals. Our attempt is to provide easy definitions on Intermittent Claudication and any other medical topic for the public at large.
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