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| This glossary contains: 19186 medical terms |
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Independent Data Monitoring Committee (IDMC)
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Independent Data Monitoring Committee (IDMC)An independent committee that may be established by the study investigators to assess at intervals the progress of a ongoing blinded clinical trial, the safety data, and the critical efficacy endpoints, and to recommend whether to continue, modify or stop a trial. See also Data and Safety Monitoring Board, Monitoring Committee, Data Monitoring.
RELATED TERMS--------------------------------------
Clinical
That which can be observed in patients. Research that uses patients to test new treatments, as opposed to laboratory testing or research in animals.
Safety
relative freedom from harm; in clinical trials, this refers to an absence of harmful side effects resulting from use of the product and may be assessed by laboratory testing of biological samples, special tests and procedures, psychiatric evaluation, and/or physical examination of subjects.
Monitoring
The act of overseeing the progress of a clinical trial, and of ensuring that it is conducted, recorded, and reported in accordance with the protocol, standard operating procedures (S0Ps), good clinical practice (GCP), and the applicable regulatory requirement(s).
SIMILAR TERMS--------------------------------------
Indemnity plan
A type of health care insurance that generally does not restrict a patient's choice of doctors and medical institutions.
Independence Regional Health Center
The Independence Regional Health Center is a hospital in Independence, Missouri, United States.
Inderal
Inderal is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): propranolol hydrochloride.
Inderal la
Inderal la is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): propranolol hydrochloride.
Inderide la 120-50
Inderide la 120-50 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrochlorothiazide; propranolol hydrochloride.
Inderide la 160-50
Inderide la 160-50 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrochlorothiazide; propranolol hydrochloride.
Inderide la 80-50
Inderide la 80-50 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrochlorothiazide; propranolol hydrochloride.
Inderide-40-25
Inderide-40-25 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrochlorothiazide; propranolol hydrochloride.
Inderide-80-25
Inderide-80-25 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrochlorothiazide; propranolol hydrochloride.
PREVIOUS AND NEXT TERMS--------------------------------------
Irradiation
Treatment by ionizing radiation, such as x-rays, or radioactive sources such as radioactive iodine seeds. See radiation therapy.
Intern
A medical doctor who has completed medical school and is in the first year of additional training.
Immunoassay
Detection and assay of substances by serological (immunological) methods; in most applications the substance in question serves as antigen, both in antibody production and in measurement of antibody by the test substance.
Impairment
A defect in organ function or whole body system, which may be temporary or permanent (eg. hemiplegia).
Inclusion criteria
The criteria that prospective subjects must meet to be eligible for participation in a study. See also exclusion criteria, admission criteria.
Independent Data Monitoring Committee (IDMC)
Institution (medical)
Any public or private entity or agency or medical or dental facility where clinical trials are conducted.
Instrumental activities of daily living (IADL)
Activities that are essential if a person is to live independently, eg. use of a telephone or public transportation, housework, cooking, financial management. See also activities of daily living (ADLs).
Intention-to-treat principle
The principle that asserts that the effect of a treatment policy can be best assessed by evaluating, on the basis of the intention to treat a subject (that is, the planned treatment regimen) rather than the actual treatment given. It has the consequence that subjects allocated to a treatment group should be followed up, assessed and analysed as members of that group irrespective of their compliance to the planned course of treatment.
Interaction (qualitative and quantitative)
The situation in which a treatment contrast (for example, difference between investigational product and control) is dependent on another factor (for example, centre). A quantitative interaction refers to the case where the magnitude of the contrast differs at the different levels of the factor, whereas for a qualitative interaction the direction of the contrast differs for at least one level of the factor.
Interim analysis
Any analysis intended to compare treatment arms with respect to efficacy or safety at any time prior to the formal completion of a trial, usually only completed in blinded trials, for a DMC review.
RELATED TERMS--------------------------------------
Clinical
That which can be observed in patients. Research that uses patients to test new treatments, as opposed to laboratory testing or research in animals.
Safety
relative freedom from harm; in clinical trials, this refers to an absence of harmful side effects resulting from use of the product and may be assessed by laboratory testing of biological samples, special tests and procedures, psychiatric evaluation, and/or physical examination of subjects.
Monitoring
The act of overseeing the progress of a clinical trial, and of ensuring that it is conducted, recorded, and reported in accordance with the protocol, standard operating procedures (S0Ps), good clinical practice (GCP), and the applicable regulatory requirement(s).
SIMILAR TERMS--------------------------------------
Indemnity plan
A type of health care insurance that generally does not restrict a patient's choice of doctors and medical institutions.
Independence Regional Health Center
The Independence Regional Health Center is a hospital in Independence, Missouri, United States.
Inderal
Inderal is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): propranolol hydrochloride.
Inderal la
Inderal la is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): propranolol hydrochloride.
Inderide la 120-50
Inderide la 120-50 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrochlorothiazide; propranolol hydrochloride.
Inderide la 160-50
Inderide la 160-50 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrochlorothiazide; propranolol hydrochloride.
Inderide la 80-50
Inderide la 80-50 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrochlorothiazide; propranolol hydrochloride.
Inderide-40-25
Inderide-40-25 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrochlorothiazide; propranolol hydrochloride.
Inderide-80-25
Inderide-80-25 is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hydrochlorothiazide; propranolol hydrochloride.
PREVIOUS AND NEXT TERMS--------------------------------------
Irradiation
Treatment by ionizing radiation, such as x-rays, or radioactive sources such as radioactive iodine seeds. See radiation therapy.
Intern
A medical doctor who has completed medical school and is in the first year of additional training.
Immunoassay
Detection and assay of substances by serological (immunological) methods; in most applications the substance in question serves as antigen, both in antibody production and in measurement of antibody by the test substance.
Impairment
A defect in organ function or whole body system, which may be temporary or permanent (eg. hemiplegia).
Inclusion criteria
The criteria that prospective subjects must meet to be eligible for participation in a study. See also exclusion criteria, admission criteria.
Independent Data Monitoring Committee (IDMC)
Institution (medical)
Any public or private entity or agency or medical or dental facility where clinical trials are conducted.
Instrumental activities of daily living (IADL)
Activities that are essential if a person is to live independently, eg. use of a telephone or public transportation, housework, cooking, financial management. See also activities of daily living (ADLs).
Intention-to-treat principle
The principle that asserts that the effect of a treatment policy can be best assessed by evaluating, on the basis of the intention to treat a subject (that is, the planned treatment regimen) rather than the actual treatment given. It has the consequence that subjects allocated to a treatment group should be followed up, assessed and analysed as members of that group irrespective of their compliance to the planned course of treatment.
Interaction (qualitative and quantitative)
The situation in which a treatment contrast (for example, difference between investigational product and control) is dependent on another factor (for example, centre). A quantitative interaction refers to the case where the magnitude of the contrast differs at the different levels of the factor, whereas for a qualitative interaction the direction of the contrast differs for at least one level of the factor.
Interim analysis
Any analysis intended to compare treatment arms with respect to efficacy or safety at any time prior to the formal completion of a trial, usually only completed in blinded trials, for a DMC review.
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This dictionary contains 19186 terms.
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