Medical Glossary

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19186
medical terms

Gilbert syndrome




Gilbert syndrome

A common but harmless genetic condition in which a liver enzyme essential to the disposal of bilirubin (the chemical that results from the normal breakdown of hemoglobin from red blood cells) is abnormal.

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Genetic
Hereditary. Having to do with the genes.

Condition
The term "condition" has a number of biomedical meanings including the following: 1.An unhealthy state, such as in "this is a progressive condition." 2.A state of fitness, such as "getting into condition." 3.Something that is essential to the occurrence of something else; essentially a "precondition." 4.As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

Liver
The largest organ in the body. The liver carries out many important functions, such as making bile, changing food into energy, and cleaning alcohol and poisons from the blood.

Enzyme
A cellular protein whose shape allows it to hold together several other molecules in close proximity to each other. In this way, enzymes are able to induce chemical reactions in other substances with little expenditure of energy and without being changed themselves. Basically, an enzyme acts as a catalyst.

Essential
1. Something that cannot be done without. 2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid. 3. Idiopathic. As in essential hypertension.

Bilirubin
The orange-yellow pigment of bile, the green fluid that aids in digestion and that is secreted by the liver. Bilirubin is formed mainly by hemoglobin breakdown at the end of red cell life and eventually most of it leaves the body in the feces. Two types are in the blood. Water insoluble or unconjugated bilirubin refers to the pigment before it reaches the liver. In the liver it is converted to the water-soluble or conjugated bilirubin which is excreted into the bile.

Hemoglobin
Hemoglobin is a substance contained within the red blood cells and is responsible for their color. It has the unique property of combining reversibly with oxygen and is the medium by which oxygen is transported within the body. It takes up oxygen as blood passes through the lungs and releases it as blood passes through the tissues.

Blood
The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.

Abnormal
Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer).



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GIFT
A technique in which the male and female cells required to begin reproduction are injected into the fallopian tubes of the female for fertilization. This technique is one of the methods doctors use to overcome infertility, the inability of couples to produce offspring on their own. The acronym GIFT stands for Gamete Intrafallopian Transfer.

Gigantism
Excessive growth both in height and specific body parts. Gigantism with extreme height may be associated with disorders of pituitary gland, which may oversecrete human growth hormone (somatotrophin) during childhood before the bones fuse. Excessive growth of specific body parts is also a feature of a number of disorders such as the Wiedemann-Beckwith syndrome in which there is macroglossia (an abnormally large tongue).

Gigantism, eunuchoid
Extremely tall stature due to the delayed onset of puberty which permits the continued growth of the long bones before their growing ends (epiphyses) fuse and growth stops.

Gigantism, focal
Excessive growth of specific body parts such as an arm, the tongue, or a combination of specific body parts as is seen in Beckwith-Wiedemann syndrome or acromegaly. This type of gigantism may occur before or after the bones fuse. If it occurs afterwards, it causes disfigurement. Surgery for mass reduction can help improve function. Other treatments may be available for specific conditions.

Gigantism, pituitary
Excessive growth and height due to chronic overactivity of the pituitary gland (at the base of the brain). (Growth hormone is specifically made by the anterior pituitary gland.) In pituitary gigantism, there is secretion of too much growth hormone before the end of adolescence. People with pituitary gigantism can truly be giants. They can sometimes end up over 7 or 8 feet in height.

Gilbert syndrome

Ginger
A perennial tropical herb that has been used as a treatment for nausea and bowel spasms.

Gingko biloba
An herb that is very popular as a treatment for dementia (a progressive brain dysfunction) and to improve thinking. Gingko can cause mild stomach upset and headache. Gingko seems also to have blood thinning properties. Therefore, it is not recommended to be taken with aspirin, nonsteroidal anti-inflammatory drugs (such as ibuprofen/Advil, Motrin or naproxen/Aleve), or medications to prevent blood clotting (anticoagulants) such as warfarin/Coumadin. Gingko should be avoided in patients with epilepsy taking seizure medicines, such as phenytoin /Dilantin, carbamazepine /Tegretol, and phenobarbital.

Ginseng
An herb that has been used to stimulate the adrenal gland and thereby increase energy. It also may have some beneficial effect on reducing blood sugar in patients with diabetes mellitus. Ginseng can cause elevation in blood pressure, headache, vomiting, insomnia, and nose bleeding. Ginseng can also cause falsely abnormal blood tests for digoxin level in persons taking the drug for heart disease. It is unclear whether ginseng may affect female hormones. Its use in pregnancy is not recommended. Ginseng may affect the action of the normal blood clotting element (platelets). It should be avoided in patients taking aspirin, nonsteroidal antiinflammatory drugs (such as ibuprofen/Advil, Motrin or naproxen/Aleve), or medications to prevent blood clotting (anticoagulants) such as warfarin/Coumadin. Ginseng may also cause headaches, tremors, nervousness, and sleeplessness. It should be avoided in persons with manic disorder and psychosis.

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This dictionary contains 19186 terms.







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