Medical Glossary

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19186
medical terms

Giant cell tumor of bone




Giant cell tumor of bone

A tumor of bone characterized by massive destruction of the end (epiphysis) of a long bone. The site most commonly struck by this tumor is the knee -- the far end of the femur and the near end of the tibia. The tumor is often coated by new bony growth. It causes pain, restricts movement, and is usually cancerous. Treatment is by surgery, usually followed by chemotherapy.

RELATED TERMS
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Tumor
Overgrowth of tissue.

Bone
Bone refers either to a hardened connective tissue or to one of the individual structures, or organs, into which it is formed, found in many animals. Bones support body structures, protect internal organs, and (in conjunction with muscles) facilitate movement; are also involved with cell formation, calcium metabolism, and mineral storage. The bones of an animal are, collectively, known as the skeleton.

Knee
The complex hinge joint of the upper and lower leg involving the femur, tibia and patella.

Femur
The thigh bone.

Tibia
The segment of the leg between the femur and the tarsus.

Pain
An unpleasant sensory or emotional experience primarily associated with tissue damage, or described in terms of tissue damage, or both.

Surgery
Treating diseases or other medical conditions by operating on a patient to remove or repair parts of the body.

Chemotherapy
The use of chemicals (medicines) to treat cancer.



SIMILAR TERMS
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Giant cell arteritis
A vasculitic disorder which presents with head pain and scalp tenderness and a high ESR. Sudden loss of vision may occur due to retinal artery occlusion. Part of the polymyalgia rheumatica disease spectrum. Also known as cranial or temporal arteritis.

Giant cell arteritis
Disease causing inflammation of the temporal arteries and other arteries in the head and neck, causing the arteries to narrow, reducing blood flow in the affected areas; may cause persistent headaches and vision loss; also known as cranial arteritis, temporal arteritis, or Horton’s disease.

Giant cell tumor, malignant
A type of bone tumor characterized by massive destruction of bone near the end (epiphysis) of a long bone. The site most commonly struck by this tumor is the knee -- the far end of the femur and the near end of the tibia. The tumor is often coated by new bony growth. It causes pain and restricts movement. Treatment is by surgery, usually followed by chemotherapy.

Giant hypertrophic gastritis
A premalignant disorder of the stomach characterized by overgrowth of the stomach lining (the gastric mucosa) and hypoalbuminemia (low blood serum level of albumin) due to loss of albumin by the stomach. The abnormalities of the stomach are highly characteristic with giant folds, excess mucus secretion by the lining of the stomach, and hypochlorhydria (decreased acid secretion by the stomach). The disease tends to lead to stomach cancer.

Giant platelet syndrome
This condition is a primary problem of platelets in which the platelets lack the ability to stick adequately to injured blood vessel walls and as a result of this problem there is abnormal bleeding.

Giantism
Abnormal growth of the body due to an excessive amount of growth hormone produced by the pituitary gland.



PREVIOUS AND NEXT TERMS
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Gestalt therapy
A psychotherapeutic concept that stresses understanding mental processes as holistic entities (gestalts) rather than as discrete steps. Gestalt therapy often uses group therapy techniques to help patients gain this type of insight.

Gestation period
The period of development of the young from the time of conception until birth. For humans the full gestation period is normally 9 months.

GFAP
Glial fibrillary acidic protein. The degenerative brain condition called Alexander disease is caused by mutation in GFAP (glial fibrillary acidic protein). The GFAP gene provides instructions for making GFAP protein, a member of the intermediate filament family that provides support and strength to cells. Several molecules of GFAP protein bind together to form the main intermediate filament found in specialized brain cells called astrocytes. Astrocytes are star-shaped cells that support the functions of nerve cells in the brain and spinal cord (central nervous system). If the central nervous system is injured through trauma or disease, astrocytes react by rapidly producing more GFAP.

GFP
Green fluorescent protein. A protein that glows green under fluorescent light. Found naturally in the jellyfish Aequorea victoria, GFP fluoresces green when exposed to blue light. It has a sequence of three amino acids (serine-tyrosine-glycine) which is responsible for its fluorescence.

GI
1. In medicine, commonly used abbreviation for gastrointestinal, referring collectively to the stomach and the small and large intestine. 2. Outside of medicine, GI may stand for galvanized iron, general issue or government issue (as in GI Joe).

Giant cell tumor of bone

Giant cell tumor, malignant
A type of bone tumor characterized by massive destruction of bone near the end (epiphysis) of a long bone. The site most commonly struck by this tumor is the knee -- the far end of the femur and the near end of the tibia. The tumor is often coated by new bony growth. It causes pain and restricts movement. Treatment is by surgery, usually followed by chemotherapy.

Giant hypertrophic gastritis
A premalignant disorder of the stomach characterized by overgrowth of the stomach lining (the gastric mucosa) and hypoalbuminemia (low blood serum level of albumin) due to loss of albumin by the stomach. The abnormalities of the stomach are highly characteristic with giant folds, excess mucus secretion by the lining of the stomach, and hypochlorhydria (decreased acid secretion by the stomach). The disease tends to lead to stomach cancer.

Giant platelet syndrome
This condition is a primary problem of platelets in which the platelets lack the ability to stick adequately to injured blood vessel walls and as a result of this problem there is abnormal bleeding.

Giardia
A genus of protozoa that infect the gastrointestinal tract of some animals, including humans. Giardia have a large sucking disk which permits them to adhere to the intestinal lining. The species that infects humans (and causes diarrhea) is Giardia lamblia.

Giardia lamblia
A parasite responsible for a contagious form of diarrhea. The parasite is most commonly transmitted through direct contact with infected feces or by eating food or drinking water contaminated by feces. Giardia is one of the most common intestinal parasites in the world. The disease is most prevalent in developing countries, where infections are associated with poor sanitary conditions, poor water quality control, and overcrowding.Giardiasis affects three times as many children as adults. It particularly affects diapered children and toddlers being toilet-trained. Families with young children who attend day-care centers are at greater risk of developing giardiasis than is the general population.

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This dictionary contains 19186 terms.







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