Medical Glossary

This glossary contains:
19186
medical terms

Germinoma




Germinoma

A type of germ cell tumor.

RELATED TERMS
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Germ
A disease-causing microorganism.

Cell
Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.

Tumor
Overgrowth of tissue.



SIMILAR TERMS
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Germ
A disease-causing microorganism.

Germ cell
Or germline cell. A sperm or egg, or a cell that can develop into a sperm or egg; all other body cells are called somatic cells.

Germ cell tumor
A tumor that arise from a germ cell. These tumors may arise within the gonads -- the ovary and testis. Most testicular tumors are, in fact, germ cell tumors. Germ cell tumors also occur in sites outside the gonads, reflecting the fact that germ cells travel to diverse areas of the body, such as the chest, abdomen, and brain.

Germ line
Refers to genes in germ cells as opposed to somatic cells, that is, genes in their unrearranged state rather than those rearranged for production of a protein.

Germa-medica
Germa-medica is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hexachlorophene.

Germa-medica "mg"
Germa-medica "mg" is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): hexachlorophene.

German measles
See rubella.

German measles immunization
The standard MMR vaccine is given to prevent measles, mumps and rubella (German measles). The MMR vaccine is now given in two dosages. The first should be given at 12-15 months of age. The second vaccination should be given at 4-6 years. Most children should receive MMR vaccinations. Exceptions may include children born with an inability to fight off infection, some children with cancer, on treatment with radiation or drugs for cancer, on long term steroids (cortisone). People with severe allergic reactions to eggs or the drug neomycin should probably avoid the MMR vaccine. Pregnant women should wait until after delivery before being immunized with MMR. People with HIV or AIDS should normally receive MMR vaccine. Measles, mumps, and rubella vaccines may be administered as individual shots, if necessary, or as a measles- rubella combination.

German measles vaccine
A vaccine designed to prevent rubella, or German measles. The rubella vaccine has since been refined into the vaccine now known as MMR for mumps, measles and rubella. The congenital rubella syndrome is now largely a chapter in the history of medicine, thanks to the rubella vaccine.

Germanium
A nonessential trace element that has caused nephrotoxicity (kidney injury) and death when used chronically by humans, even at recommended levels of use.

Germantown Health Care Center
The Germantown Health Care Center is a hospital in Philadelphia, Pennsylvania, United States.

Germantown Hospital and Medical Center
The Germantown Hospital and Medical Center is a hospital in Philadelphia, Pennsylvania, United States.

Germantown Mediq Mri Center
The Germantown Mediq Mri Center is a hospital in Philadelphia, Pennsylvania, United States.

Germinal vesicle transfer
Or oocyte nuclear transfer. An assisted reproductive technique involving transfer of an egg nucleus (usually from a woman with age-related infertility or mitochondrial disease) into a healthy donor egg whose nucleus has been removed. This reconstituted egg can then be fertilized by a sperm in vitro. This technique may restore fertility to older women or to prevent the passing of mitochondrial disease to offspring.

Germline cell
Or germ cell. A sperm or egg, or a cell that can develop into a sperm or egg; all other body cells are called somatic cells.

Germline mutation
A heritable change in the DNA that occurred in a germ cell (a cell destined to become an egg or in the sperm) or the zygote (the conceptus) at the single-cell stage. When transmitted to a child, a germline mutation is incorporated in every cell of their body. Germline mutations play a key role in genetic diseases. They play a role, too, in certain types of cancer as, for example, the eye tumor retinoblastoma and Wilms tumor, a childhood malignancy of the kidney. A germline mutation is in contrast to a somatic mutation which is acquired in a single body cell.



PREVIOUS AND NEXT TERMS
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Geriatric medicine
The branch of medicine concerned with the diagnosis, treatment and prevention of disease in older people and the problems specific to aging. Also called geriatrics.

Germ cell tumor
A tumor that arise from a germ cell. These tumors may arise within the gonads -- the ovary and testis. Most testicular tumors are, in fact, germ cell tumors. Germ cell tumors also occur in sites outside the gonads, reflecting the fact that germ cells travel to diverse areas of the body, such as the chest, abdomen, and brain.

German measles immunization
The standard MMR vaccine is given to prevent measles, mumps and rubella (German measles). The MMR vaccine is now given in two dosages. The first should be given at 12-15 months of age. The second vaccination should be given at 4-6 years. Most children should receive MMR vaccinations. Exceptions may include children born with an inability to fight off infection, some children with cancer, on treatment with radiation or drugs for cancer, on long term steroids (cortisone). People with severe allergic reactions to eggs or the drug neomycin should probably avoid the MMR vaccine. Pregnant women should wait until after delivery before being immunized with MMR. People with HIV or AIDS should normally receive MMR vaccine. Measles, mumps, and rubella vaccines may be administered as individual shots, if necessary, or as a measles- rubella combination.

German measles vaccine
A vaccine designed to prevent rubella, or German measles. The rubella vaccine has since been refined into the vaccine now known as MMR for mumps, measles and rubella. The congenital rubella syndrome is now largely a chapter in the history of medicine, thanks to the rubella vaccine.

Germanium
A nonessential trace element that has caused nephrotoxicity (kidney injury) and death when used chronically by humans, even at recommended levels of use.

Germinoma

Germline mutation
A heritable change in the DNA that occurred in a germ cell (a cell destined to become an egg or in the sperm) or the zygote (the conceptus) at the single-cell stage. When transmitted to a child, a germline mutation is incorporated in every cell of their body. Germline mutations play a key role in genetic diseases. They play a role, too, in certain types of cancer as, for example, the eye tumor retinoblastoma and Wilms tumor, a childhood malignancy of the kidney. A germline mutation is in contrast to a somatic mutation which is acquired in a single body cell.

Gerstmann-Straussler-Scheinker syndrome
A rare familial form of progressive dementia inherited in an autosomal dominant manner due to a mutant prion gene on chromosome 20pter-p12. Abbreviated GSS. Degeneration of the nervous system usually starts in the fourth or fifth decade of life with slowly developing dysarthria (difficulty speaking) and cerebellar ataxia (wobbliness) and later the progressive dementia become evident. Death usually occurs within 10 years of the onset of symptoms.

Gestalt therapy
A psychotherapeutic concept that stresses understanding mental processes as holistic entities (gestalts) rather than as discrete steps. Gestalt therapy often uses group therapy techniques to help patients gain this type of insight.

Gestation period
The period of development of the young from the time of conception until birth. For humans the full gestation period is normally 9 months.

GFAP
Glial fibrillary acidic protein. The degenerative brain condition called Alexander disease is caused by mutation in GFAP (glial fibrillary acidic protein). The GFAP gene provides instructions for making GFAP protein, a member of the intermediate filament family that provides support and strength to cells. Several molecules of GFAP protein bind together to form the main intermediate filament found in specialized brain cells called astrocytes. Astrocytes are star-shaped cells that support the functions of nerve cells in the brain and spinal cord (central nervous system). If the central nervous system is injured through trauma or disease, astrocytes react by rapidly producing more GFAP.

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This dictionary contains 19186 terms.







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