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| This glossary contains: 19186 medical terms |
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Gelineau syndrome
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Gelineau syndromeA neurological disorder marked by a sudden recurrent uncontrollable compulsion to sleep. Also known as narcolepsy. The disorder is often associated with cataplexy (a sudden loss of muscle tone and paralysis of voluntary muscles associated with a strong emotion), sleep paralysis (immobility of the body that occurs in the transition from sleep to wakefulness), what are called hypnagogic hallucinations (pre-sleep dreams) and automatic behaviors (such as doing something "automatically" and not remembering afterwards how one did it).
RELATED TERMS--------------------------------------
Neurological
The medical science that deals with the nervous system and disorders affecting it.
Compulsion
Repetitive ritualistic behavior such as hand washing or ordering or a mental act such as praying or repeating words silently that aims to prevent or reduce distress or prevent some dreaded event or situation. The person feels driven to perform such actions in response to an obsession or according to rules that must be applied rigidly, even though the behaviors are recognized to be excessive or unreasonable.
Narcolepsy
Narcolepsy is a neurological disorder of sleep regulation that affects the control of sleep and wakefulness. The four classic symptoms are excessive daytime sleepiness, cataplexy, sleep paralysis and hypnagogic hallucinations.
Cataplexy
Episodes of sudden bilateral loss of muscle tone resulting in the individual collapsing, often in association with intense emotions such as laughter, anger, fear, or surprise.
Muscle
Tissue made up of bundles of long, slender cells that contract when stimulated.
Paralysis
Inability to move parts of the body.
Hypnagogic
Referring to the semiconscious state immediately preceding sleep; may include hallucinations that are of no pathological significance.
SIMILAR TERMS--------------------------------------
Gelisim Hastanesi
The Gelisim Hastanesi is a hospital in Bahcelievler, Istanbul, Turkey.
PREVIOUS AND NEXT TERMS--------------------------------------
GBV-C
GB virus C is genetically related to the hepatitis C virus but which does not cause hepatitis and, in fact, is not known to be responsible for any disease. Infection with GB virus C (GBV-C) seems to be beneficial to HIV-infected patients. They enjoy longer survival if they are coinfected with this virus and HIV than if they have HIV alone. GB virus C (GBV-C) is also called hepatitis G. However, the designation GB virus C (GBV-C) is preferred because the virus is not a cause of hepatitis.
GDF-8
The gene encoding growth and differentiation factor, also known as myostatin.
Gefitinib
A drug that attaches to the epidermal growth factor receptor (EGFR) on the surfaces of cells. The drug was designed to treat non-small-cell lung cancer. Marketed under the brand name Iressa.
Geiger counter
The most commonly used portable radiation detection and measuring instrument, consisting of a gas-filled tube containing electrodes, between which an electrical voltage but no current flows. When ionizing radiation passes through the tube, a short, intense pulse of current passes from the negative electrode to the positive electrode and is measured or counted. The number of pulses per second measures the intensity of the radiation field. Geiger counters are highly sensitive to beta particles but relatively insensitive to gamma rays and x-rays.
Gel electrophoresis
The process in which molecules (such as proteins, DNA, or RNA fragments) can be separated according to size and electrical charge by applying an electric current to them while they are in a gel. The current forces the molecules through pores in a thin layer of gel, a firm jelly-like substance. The gel can be made so that its pores are just the right dimensions for separating molecules within a specific range of sizes and shapes. Smaller fragments usually travel further than large ones.
Gelineau syndrome
Gene amplification
Making multiple copies of a gene. Repeated copying of a gene. Gene amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events. Amplification can occur in vivo (in the living individual) or in vitro (literally "in glass", or in a plastic vessel in the laboratory).
Gene array analysis
A way of analyzing the differential expression of thousands of species of mRNA (messenger RNA) at the same time in two different samples (as, for example, in normal vs. tumor tissue, or at different developmental stages). Gene array analysis involves synthesizing labeled cDNA (complementary DNA) from 2 or more sources, and hybridizing them to identical gene arrays. This procedure can be done in standard molecular biology laboratories with basic instrumentation.
Gene deletion
The total loss (or absence) of a gene. Gene deletion plays a role in birth defects and in the development of cancer.
Gene duplication
An extra copy of a gene. Gene duplication is a key mechanism in evolution. Once a gene is duplicated, the identical genes can undergo changes and diverge to create two different genes.
Gene family
A group of genes related in structure and often in function. The genes belonging to a gene family are descended from an ancestral gene. For example, the hemoglobin genes of critical importance to red blood cells belong to one gene family created by gene duplication (making extra copies of a gene) and divergence (divergent changes in the copies of the gene).
RELATED TERMS--------------------------------------
Neurological
The medical science that deals with the nervous system and disorders affecting it.
Compulsion
Repetitive ritualistic behavior such as hand washing or ordering or a mental act such as praying or repeating words silently that aims to prevent or reduce distress or prevent some dreaded event or situation. The person feels driven to perform such actions in response to an obsession or according to rules that must be applied rigidly, even though the behaviors are recognized to be excessive or unreasonable.
Narcolepsy
Narcolepsy is a neurological disorder of sleep regulation that affects the control of sleep and wakefulness. The four classic symptoms are excessive daytime sleepiness, cataplexy, sleep paralysis and hypnagogic hallucinations.
Cataplexy
Episodes of sudden bilateral loss of muscle tone resulting in the individual collapsing, often in association with intense emotions such as laughter, anger, fear, or surprise.
Muscle
Tissue made up of bundles of long, slender cells that contract when stimulated.
Paralysis
Inability to move parts of the body.
Hypnagogic
Referring to the semiconscious state immediately preceding sleep; may include hallucinations that are of no pathological significance.
SIMILAR TERMS--------------------------------------
Gelisim Hastanesi
The Gelisim Hastanesi is a hospital in Bahcelievler, Istanbul, Turkey.
PREVIOUS AND NEXT TERMS--------------------------------------
GBV-C
GB virus C is genetically related to the hepatitis C virus but which does not cause hepatitis and, in fact, is not known to be responsible for any disease. Infection with GB virus C (GBV-C) seems to be beneficial to HIV-infected patients. They enjoy longer survival if they are coinfected with this virus and HIV than if they have HIV alone. GB virus C (GBV-C) is also called hepatitis G. However, the designation GB virus C (GBV-C) is preferred because the virus is not a cause of hepatitis.
GDF-8
The gene encoding growth and differentiation factor, also known as myostatin.
Gefitinib
A drug that attaches to the epidermal growth factor receptor (EGFR) on the surfaces of cells. The drug was designed to treat non-small-cell lung cancer. Marketed under the brand name Iressa.
Geiger counter
The most commonly used portable radiation detection and measuring instrument, consisting of a gas-filled tube containing electrodes, between which an electrical voltage but no current flows. When ionizing radiation passes through the tube, a short, intense pulse of current passes from the negative electrode to the positive electrode and is measured or counted. The number of pulses per second measures the intensity of the radiation field. Geiger counters are highly sensitive to beta particles but relatively insensitive to gamma rays and x-rays.
Gel electrophoresis
The process in which molecules (such as proteins, DNA, or RNA fragments) can be separated according to size and electrical charge by applying an electric current to them while they are in a gel. The current forces the molecules through pores in a thin layer of gel, a firm jelly-like substance. The gel can be made so that its pores are just the right dimensions for separating molecules within a specific range of sizes and shapes. Smaller fragments usually travel further than large ones.
Gelineau syndrome
Gene amplification
Making multiple copies of a gene. Repeated copying of a gene. Gene amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events. Amplification can occur in vivo (in the living individual) or in vitro (literally "in glass", or in a plastic vessel in the laboratory).
Gene array analysis
A way of analyzing the differential expression of thousands of species of mRNA (messenger RNA) at the same time in two different samples (as, for example, in normal vs. tumor tissue, or at different developmental stages). Gene array analysis involves synthesizing labeled cDNA (complementary DNA) from 2 or more sources, and hybridizing them to identical gene arrays. This procedure can be done in standard molecular biology laboratories with basic instrumentation.
Gene deletion
The total loss (or absence) of a gene. Gene deletion plays a role in birth defects and in the development of cancer.
Gene duplication
An extra copy of a gene. Gene duplication is a key mechanism in evolution. Once a gene is duplicated, the identical genes can undergo changes and diverge to create two different genes.
Gene family
A group of genes related in structure and often in function. The genes belonging to a gene family are descended from an ancestral gene. For example, the hemoglobin genes of critical importance to red blood cells belong to one gene family created by gene duplication (making extra copies of a gene) and divergence (divergent changes in the copies of the gene).
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This dictionary contains 19186 terms.
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