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Gel electrophoresis
Gel electrophoresisThe process in which molecules (such as proteins, DNA, or RNA fragments) can be separated according to size and electrical charge by applying an electric current to them while they are in a gel. The current forces the molecules through pores in a thin layer of gel, a firm jelly-like substance. The gel can be made so that its pores are just the right dimensions for separating molecules within a specific range of sizes and shapes. Smaller fragments usually travel further than large ones. RELATED TERMS-------------------------------------- DNA Deoxyribo-Nucleic acid. DNA molecules carry the genetic information necessary for the organization and functioning of most living cells and control the inheritance of characteristics. SIMILAR TERMS-------------------------------------- PREVIOUS AND NEXT TERMS-------------------------------------- GB virus C A virus related to the hepatitis C virus but which does not cause hepatitis and, in fact, is not known to be responsible for any disease. Infection with GB virus C (GBV-C) is beneficial to HIV-infected patients. They enjoy longer survival if they are coinfected with this virus and HIV than if they have HIV alone. Having two viruses is better than one here. Having both HIV and GB virus C is better than having HIV alone. GB virus C (GBV-C) is also called hepatitis G. However, the designation GB virus C (GBV-C) is preferred because the virus is not a cause of hepatitis. GBV-C GB virus C is genetically related to the hepatitis C virus but which does not cause hepatitis and, in fact, is not known to be responsible for any disease. Infection with GB virus C (GBV-C) seems to be beneficial to HIV-infected patients. They enjoy longer survival if they are coinfected with this virus and HIV than if they have HIV alone. GB virus C (GBV-C) is also called hepatitis G. However, the designation GB virus C (GBV-C) is preferred because the virus is not a cause of hepatitis. GDF-8 The gene encoding growth and differentiation factor, also known as myostatin. Gefitinib A drug that attaches to the epidermal growth factor receptor (EGFR) on the surfaces of cells. The drug was designed to treat non-small-cell lung cancer. Marketed under the brand name Iressa. Geiger counter The most commonly used portable radiation detection and measuring instrument, consisting of a gas-filled tube containing electrodes, between which an electrical voltage but no current flows. When ionizing radiation passes through the tube, a short, intense pulse of current passes from the negative electrode to the positive electrode and is measured or counted. The number of pulses per second measures the intensity of the radiation field. Geiger counters are highly sensitive to beta particles but relatively insensitive to gamma rays and x-rays. Gel electrophoresis Gelineau syndrome A neurological disorder marked by a sudden recurrent uncontrollable compulsion to sleep. Also known as narcolepsy. The disorder is often associated with cataplexy (a sudden loss of muscle tone and paralysis of voluntary muscles associated with a strong emotion), sleep paralysis (immobility of the body that occurs in the transition from sleep to wakefulness), what are called hypnagogic hallucinations (pre-sleep dreams) and automatic behaviors (such as doing something "automatically" and not remembering afterwards how one did it). Gene amplification Making multiple copies of a gene. Repeated copying of a gene. Gene amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events. Amplification can occur in vivo (in the living individual) or in vitro (literally "in glass", or in a plastic vessel in the laboratory). Gene array analysis A way of analyzing the differential expression of thousands of species of mRNA (messenger RNA) at the same time in two different samples (as, for example, in normal vs. tumor tissue, or at different developmental stages). Gene array analysis involves synthesizing labeled cDNA (complementary DNA) from 2 or more sources, and hybridizing them to identical gene arrays. This procedure can be done in standard molecular biology laboratories with basic instrumentation. Gene deletion The total loss (or absence) of a gene. Gene deletion plays a role in birth defects and in the development of cancer. Gene duplication An extra copy of a gene. Gene duplication is a key mechanism in evolution. Once a gene is duplicated, the identical genes can undergo changes and diverge to create two different genes. We thank you for using the Medical Glossary to search for Gel electrophoresis. If you have a better definition for Gel electrophoresis than the one presented here, please let us know by making use of the suggest a term option. This definition of Gel electrophoresis may be disputed by other professionals. Our attempt is to provide easy definitions on Gel electrophoresis and any other medical topic for the public at large.
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