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| This glossary contains: 19186 medical terms |
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Gefitinib
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GefitinibA drug that attaches to the epidermal growth factor receptor (EGFR) on the surfaces of cells. The drug was designed to treat non-small-cell lung cancer. Marketed under the brand name Iressa.
RELATED TERMS--------------------------------------
Epidermal
Pertaining to the epidermis, the outermost layer of the skin.
Receptor
A molecule that recognizes a unique hormone. Once that hormone is bound to the receptor, the information carried by the hormone can now exert its biological action.
Cancer
Any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream.
Iressa
Iressa is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): gefitinib.
SIMILAR TERMS--------------------------------------
PREVIOUS AND NEXT TERMS--------------------------------------
Gay gene
A gene located on the X chromosome which was alleged to determine male homosexuality. The "gay gene" was dubbed homosexuality 1 (HMS1) and the male sexual orientation gene. It was thought to be in chromosome band Xq28. However, one would expect there to be strong selective pressures against a gene for male homosexual orientation. The original claim for the "gay gene" was made in 1993 by Dean H. Hamer and colleagues. There has been no independent confirmation of the existence of a "gay gene" and today there is considerable doubt about its existence.
Gay suicide risk
High rates of suicide have consistently been reported among homosexuals, particularly among adolescents and young adults.
GB virus C
A virus related to the hepatitis C virus but which does not cause hepatitis and, in fact, is not known to be responsible for any disease. Infection with GB virus C (GBV-C) is beneficial to HIV-infected patients. They enjoy longer survival if they are coinfected with this virus and HIV than if they have HIV alone. Having two viruses is better than one here. Having both HIV and GB virus C is better than having HIV alone. GB virus C (GBV-C) is also called hepatitis G. However, the designation GB virus C (GBV-C) is preferred because the virus is not a cause of hepatitis.
GBV-C
GB virus C is genetically related to the hepatitis C virus but which does not cause hepatitis and, in fact, is not known to be responsible for any disease. Infection with GB virus C (GBV-C) seems to be beneficial to HIV-infected patients. They enjoy longer survival if they are coinfected with this virus and HIV than if they have HIV alone. GB virus C (GBV-C) is also called hepatitis G. However, the designation GB virus C (GBV-C) is preferred because the virus is not a cause of hepatitis.
GDF-8
The gene encoding growth and differentiation factor, also known as myostatin.
Gefitinib
Geiger counter
The most commonly used portable radiation detection and measuring instrument, consisting of a gas-filled tube containing electrodes, between which an electrical voltage but no current flows. When ionizing radiation passes through the tube, a short, intense pulse of current passes from the negative electrode to the positive electrode and is measured or counted. The number of pulses per second measures the intensity of the radiation field. Geiger counters are highly sensitive to beta particles but relatively insensitive to gamma rays and x-rays.
Gel electrophoresis
The process in which molecules (such as proteins, DNA, or RNA fragments) can be separated according to size and electrical charge by applying an electric current to them while they are in a gel. The current forces the molecules through pores in a thin layer of gel, a firm jelly-like substance. The gel can be made so that its pores are just the right dimensions for separating molecules within a specific range of sizes and shapes. Smaller fragments usually travel further than large ones.
Gelineau syndrome
A neurological disorder marked by a sudden recurrent uncontrollable compulsion to sleep. Also known as narcolepsy. The disorder is often associated with cataplexy (a sudden loss of muscle tone and paralysis of voluntary muscles associated with a strong emotion), sleep paralysis (immobility of the body that occurs in the transition from sleep to wakefulness), what are called hypnagogic hallucinations (pre-sleep dreams) and automatic behaviors (such as doing something "automatically" and not remembering afterwards how one did it).
Gene amplification
Making multiple copies of a gene. Repeated copying of a gene. Gene amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events. Amplification can occur in vivo (in the living individual) or in vitro (literally "in glass", or in a plastic vessel in the laboratory).
Gene array analysis
A way of analyzing the differential expression of thousands of species of mRNA (messenger RNA) at the same time in two different samples (as, for example, in normal vs. tumor tissue, or at different developmental stages). Gene array analysis involves synthesizing labeled cDNA (complementary DNA) from 2 or more sources, and hybridizing them to identical gene arrays. This procedure can be done in standard molecular biology laboratories with basic instrumentation.
RELATED TERMS--------------------------------------
Epidermal
Pertaining to the epidermis, the outermost layer of the skin.
Receptor
A molecule that recognizes a unique hormone. Once that hormone is bound to the receptor, the information carried by the hormone can now exert its biological action.
Cancer
Any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream.
Iressa
Iressa is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): gefitinib.
SIMILAR TERMS--------------------------------------
PREVIOUS AND NEXT TERMS--------------------------------------
Gay gene
A gene located on the X chromosome which was alleged to determine male homosexuality. The "gay gene" was dubbed homosexuality 1 (HMS1) and the male sexual orientation gene. It was thought to be in chromosome band Xq28. However, one would expect there to be strong selective pressures against a gene for male homosexual orientation. The original claim for the "gay gene" was made in 1993 by Dean H. Hamer and colleagues. There has been no independent confirmation of the existence of a "gay gene" and today there is considerable doubt about its existence.
Gay suicide risk
High rates of suicide have consistently been reported among homosexuals, particularly among adolescents and young adults.
GB virus C
A virus related to the hepatitis C virus but which does not cause hepatitis and, in fact, is not known to be responsible for any disease. Infection with GB virus C (GBV-C) is beneficial to HIV-infected patients. They enjoy longer survival if they are coinfected with this virus and HIV than if they have HIV alone. Having two viruses is better than one here. Having both HIV and GB virus C is better than having HIV alone. GB virus C (GBV-C) is also called hepatitis G. However, the designation GB virus C (GBV-C) is preferred because the virus is not a cause of hepatitis.
GBV-C
GB virus C is genetically related to the hepatitis C virus but which does not cause hepatitis and, in fact, is not known to be responsible for any disease. Infection with GB virus C (GBV-C) seems to be beneficial to HIV-infected patients. They enjoy longer survival if they are coinfected with this virus and HIV than if they have HIV alone. GB virus C (GBV-C) is also called hepatitis G. However, the designation GB virus C (GBV-C) is preferred because the virus is not a cause of hepatitis.
GDF-8
The gene encoding growth and differentiation factor, also known as myostatin.
Gefitinib
Geiger counter
The most commonly used portable radiation detection and measuring instrument, consisting of a gas-filled tube containing electrodes, between which an electrical voltage but no current flows. When ionizing radiation passes through the tube, a short, intense pulse of current passes from the negative electrode to the positive electrode and is measured or counted. The number of pulses per second measures the intensity of the radiation field. Geiger counters are highly sensitive to beta particles but relatively insensitive to gamma rays and x-rays.
Gel electrophoresis
The process in which molecules (such as proteins, DNA, or RNA fragments) can be separated according to size and electrical charge by applying an electric current to them while they are in a gel. The current forces the molecules through pores in a thin layer of gel, a firm jelly-like substance. The gel can be made so that its pores are just the right dimensions for separating molecules within a specific range of sizes and shapes. Smaller fragments usually travel further than large ones.
Gelineau syndrome
A neurological disorder marked by a sudden recurrent uncontrollable compulsion to sleep. Also known as narcolepsy. The disorder is often associated with cataplexy (a sudden loss of muscle tone and paralysis of voluntary muscles associated with a strong emotion), sleep paralysis (immobility of the body that occurs in the transition from sleep to wakefulness), what are called hypnagogic hallucinations (pre-sleep dreams) and automatic behaviors (such as doing something "automatically" and not remembering afterwards how one did it).
Gene amplification
Making multiple copies of a gene. Repeated copying of a gene. Gene amplification plays a role in cancer cells. A tumor cell amplifies, or copies, DNA segments as a result of cell signals and sometimes environmental events. Amplification can occur in vivo (in the living individual) or in vitro (literally "in glass", or in a plastic vessel in the laboratory).
Gene array analysis
A way of analyzing the differential expression of thousands of species of mRNA (messenger RNA) at the same time in two different samples (as, for example, in normal vs. tumor tissue, or at different developmental stages). Gene array analysis involves synthesizing labeled cDNA (complementary DNA) from 2 or more sources, and hybridizing them to identical gene arrays. This procedure can be done in standard molecular biology laboratories with basic instrumentation.
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This dictionary contains 19186 terms.
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