Medical Glossary

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GIFT




GIFT

A technique in which the male and female cells required to begin reproduction are injected into the fallopian tubes of the female for fertilization. This technique is one of the methods doctors use to overcome infertility, the inability of couples to produce offspring on their own. The acronym GIFT stands for Gamete Intrafallopian Transfer.

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Female
The traditional definition of female was "an individual of the sex that bears young" or "that produces ova or eggs". However, things are not so simple today. Female can be defined by physical appearance, by chromosome constitution (see Female chromosome complement), or by gender identification. Female chromosome complement: The large majority of females have a 46, XX chromosome complement (46 chromosomes including two X chromosomes). A minority of females have other chromosome constitutions such as 45,X (45 chromosomes including only one X chromosome) and 47,XXX (47 chromosomes including three X chromosomes).

Fertilization
The combining of the genetic material carried by sperm and egg to create an embryo. Normally occurs inside the fallopian tube (in vivo) but may also occur in a petri dish (in vitro).

Infertility
The diminished or absent ability to conceive or produce an offspring while sterility is the complete inability to conceive or produce an offspring.

GIFT
A technique in which the male and female cells required to begin reproduction are injected into the fallopian tubes of the female for fertilization. This technique is one of the methods doctors use to overcome infertility, the inability of couples to produce offspring on their own. The acronym GIFT stands for Gamete Intrafallopian Transfer.

Gamete
Sperm and eggs. These cells have the special property of carrying only one copy of each gene instead the two copies that most other cells carry. These cells contribute to the next generation and are also called “germ line” cells.



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Giant cell tumor, malignant
A type of bone tumor characterized by massive destruction of bone near the end (epiphysis) of a long bone. The site most commonly struck by this tumor is the knee -- the far end of the femur and the near end of the tibia. The tumor is often coated by new bony growth. It causes pain and restricts movement. Treatment is by surgery, usually followed by chemotherapy.

Giant hypertrophic gastritis
A premalignant disorder of the stomach characterized by overgrowth of the stomach lining (the gastric mucosa) and hypoalbuminemia (low blood serum level of albumin) due to loss of albumin by the stomach. The abnormalities of the stomach are highly characteristic with giant folds, excess mucus secretion by the lining of the stomach, and hypochlorhydria (decreased acid secretion by the stomach). The disease tends to lead to stomach cancer.

Giant platelet syndrome
This condition is a primary problem of platelets in which the platelets lack the ability to stick adequately to injured blood vessel walls and as a result of this problem there is abnormal bleeding.

Giardia
A genus of protozoa that infect the gastrointestinal tract of some animals, including humans. Giardia have a large sucking disk which permits them to adhere to the intestinal lining. The species that infects humans (and causes diarrhea) is Giardia lamblia.

Giardia lamblia
A parasite responsible for a contagious form of diarrhea. The parasite is most commonly transmitted through direct contact with infected feces or by eating food or drinking water contaminated by feces. Giardia is one of the most common intestinal parasites in the world. The disease is most prevalent in developing countries, where infections are associated with poor sanitary conditions, poor water quality control, and overcrowding.Giardiasis affects three times as many children as adults. It particularly affects diapered children and toddlers being toilet-trained. Families with young children who attend day-care centers are at greater risk of developing giardiasis than is the general population.

GIFT

Gigantism
Excessive growth both in height and specific body parts. Gigantism with extreme height may be associated with disorders of pituitary gland, which may oversecrete human growth hormone (somatotrophin) during childhood before the bones fuse. Excessive growth of specific body parts is also a feature of a number of disorders such as the Wiedemann-Beckwith syndrome in which there is macroglossia (an abnormally large tongue).

Gigantism, eunuchoid
Extremely tall stature due to the delayed onset of puberty which permits the continued growth of the long bones before their growing ends (epiphyses) fuse and growth stops.

Gigantism, focal
Excessive growth of specific body parts such as an arm, the tongue, or a combination of specific body parts as is seen in Beckwith-Wiedemann syndrome or acromegaly. This type of gigantism may occur before or after the bones fuse. If it occurs afterwards, it causes disfigurement. Surgery for mass reduction can help improve function. Other treatments may be available for specific conditions.

Gigantism, pituitary
Excessive growth and height due to chronic overactivity of the pituitary gland (at the base of the brain). (Growth hormone is specifically made by the anterior pituitary gland.) In pituitary gigantism, there is secretion of too much growth hormone before the end of adolescence. People with pituitary gigantism can truly be giants. They can sometimes end up over 7 or 8 feet in height.

Gilbert syndrome
A common but harmless genetic condition in which a liver enzyme essential to the disposal of bilirubin (the chemical that results from the normal breakdown of hemoglobin from red blood cells) is abnormal.

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This dictionary contains 19186 terms.







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