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Fibula
Fibula Smaller of the two bones in the lower leg; runs from the knee to the ankle along the outside of the lower leg. RELATED TERMS-------------------------------------- Leg The portion of the lower extremity between the knee and ankle. Knee The complex hinge joint of the upper and lower leg involving the femur, tibia and patella. Ankle A gliding joint between the distal ends of the tibia and fibula and the proximal end of the talus. SIMILAR TERMS-------------------------------------- Fibulin 3 A protein that belongs to a family of extracellular proteins expressed in the basement membranes of blood vessels. The gene that encodes fibulin 3 is FBLN3 (or EFEMP1). FBLN3 is located on chromosome 2 in band 2p16. A single mutation in FBLN3 is responsible for an autosomal dominant form of macular degeneration. Fibulin 5 A protein that belongs to a family of extracellular proteins expressed in the basement membranes of blood vessels. Fibulin 5 may be essential for the polymerization of elastin. Missense mutations in FBLN5, the gene that encodes fibulin 5, appear responsible for 1-2% of cases of age-related macular degeneration (AMD). FBLN5 is located on chromosome 14 in band 14q32.1. PREVIOUS AND NEXT TERMS-------------------------------------- Fertilization The combining of the genetic material carried by sperm and egg to create an embryo. Normally occurs inside the fallopian tube (in vivo) but may also occur in a petri dish (in vitro). Fibromyalgia Fibromyalgia is a debilitating chronic syndrome (constellation of signs and symptoms) characterized by diffuse pain, fatigue, and a wide range of other symptoms. It is not contagious, and recent studies suggest that people with fibromyalgia may be genetically predispose. It affects more women than men, with a ratio globally of 3-5:1. Fibromyalgia is seen in 3-10% of the general population, and is mostly found between the ages 20 and 50. Farsightedness Hyperopia occurs when the eyeball is too short from front to back, or the eye's focusing mechanism is too weak, causing light rays to be focused behind, rather than on the retina. People with hyperopia have difficulty seeing objects close up. Fanconi anemia A rare inherited type of aplastic anemia that is often but not always associated with skeletal abnormalities. Fanconi anemia carries an increased risk to the patient of developing acute myelogenous leukemia. The disorder may be treated by stem cell transplantation. Forensics Forensics or forensic science is the application of science to questions which are of interest to the legal system. For example, forensic pathology is the study of the human body to determine cause and manner of death. Criminalistics is the application of various sciences to answer questions relating to examination and comparison of biological evidence, trace evidence, impression evidence, drugs and firearms. Forensic odontology is the study of the uniqueness of dentition. Etcetera. Fibula Foot The distal portion of the leg, upon which an individual stands and walks. It consists, in man, of the tarsus, metatarsus, and phalanges and the tissues encompassing them. Fibrositis Inflammation of fibrous connective tissues in muscles. It often affects the muscles of the trunk and back. It may be a symptom of another disease, such as Sciatica, but in most cases the cause is unknown. Pain and stiffness. Fifth disease Slapped cheek disease (erythema infectiosum) is also known as fifth disease because it was the last of five "red rash" childhood diseases to be defined after scarlet fever, measles, rubella, and roseola. It is characterised by fever and red cheeks. Foot and Mouth disease Foot-and-mouth disease is a severe, highly communicable viral disease of cattle and swine. It also affects sheep, goats, deer and other cloven-hooved ruminants. The disease is characterized by fever and blister-like lesions followed by erosions on the tongue and lips, in the mouth, on the teats and between the hooves. Many affected animals recover, but the disease leaves them debilitated. It causes severe losses in the production of meat and milk. The disease is caused by a virus. There are at least seven separate types and many subtypes of the FMD virus. Fetal Alcohol Syndrome (FAS) A pattern of retarded growth and development, both mental and physical, with cranial, facial, 1imb, and cardiovascular defects, found in some children of mothers whose alcohol consumption during pregnancy can be classed as hazardous. The commonest abnormalities are: prenatal and postnatal growth deficiency, microcephaly, developmental delay or mental retardation, short palpebral fissures, a short upturned nose with sunken nasal bridge and a thin upper lip, abnormal palmar creases, and cardiac (especially septal) defects. Many other more subtle abnormalities have also been attributed to the effects of alcohol on the fetus. We thank you for using the Medical Glossary to search for Fibula. If you have a better definition for Fibula than the one presented here, please let us know by making use of the suggest a term option. This definition of Fibula may be disputed by other professionals. Our attempt is to provide easy definitions on Fibula and any other medical topic for the public at large.
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