Medical Glossary

This glossary contains:
19186
medical terms

Fatty aldehyde dehydrogenase deficiency



Fatty aldehyde dehydrogenase deficiency

Also known as the Sjogren-Larsson syndrome, this is a genetic (inherited) disease usually characterized by a triad of clinical findings consisting of ichthyosis (thickened fish-like skin), spastic paraplegia (spasticity of the legs) and mental retardation.

RELATED TERMS
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Syndrome
A grouping of signs and symptoms, based on their frequent co-occurrence, that may suggest a common underlying pathogenesis, course, familial pattern, or treatment selection.

Genetic
Hereditary. Having to do with the genes.

Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Triad
Triad is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): acetaminophen; butalbital; caffeine.

Clinical
That which can be observed in patients. Research that uses patients to test new treatments, as opposed to laboratory testing or research in animals.

Ichthyosis
An inherited skin disorder that produces dry, rough, scaly skin.

Paraplegia
Paraplegiai nvolves a loss of sensation and movement in the legs and in part or all of the trunk. This varies according to the level of the injury. Generally, the lower the injury, the less the loss of movement and sensation. Paraplegia usually results from an injury to the spinal cord in the mid and lower back.

Retardation
Delay or halt of any process such as mental or physical development.



SIMILAR TERMS
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Fatty Acid
A building block of fat.

Fatty acid
A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.

Fatty acid, trans
An unhealthy substance, also known as trans fat, made through the chemical process of hydrogenation of oils. Hydrogenation solidifies liquid oils and increases the shelf life and the flavor stability of oils and foods that contain them. Trans fat is found in vegetable shortenings and in some margarines, crackers, cookies, snack foods and other foods.

Fatty Acids
A basic unit of fats. When insulin levels are too low or there is not enough glucose (sugar) to use for energy, the body burns fatty acids for energy. The body then makes ketone bodies, waste products that cause the acid level in the blood to become too high. This in turn may lead to ketoacidosis, a serious problem.

Fatty acids
Molecules that are long chains of lipid-carboxylic acid found in fats and oils and in cell membranes as a component of phospholipids and glycolipids.

Fatty acids,omega-3
A class of fatty acids found in fish oils, especially from salmon and other cold-water fish, that acts to lower the levels of cholesterol and LDL (low-density lipoproteins) in the blood.

Fatty alcohol
Fatty alcohol: NAD+ oxidoreductase deficiency. Clinically known as the Sjogren-Larsson syndrome, this is a genetic (inherited) disease usually characterized by a triad of findings consisting of ichthyosis (thickened fish-like skin), spastic paraplegia (spasticity of the legs) and mental retardation.

Fatty liver
The buildup of fat in liver cells. The most common cause is alcoholism. Other causes include obesity, diabetes, and pregnancy. Also called steatosis.

Fatty liver of pregnancy, acute
Liver failure in late pregnancy, usually from unknown cause. Acute fatty liver of pregnancy (AFLP) typically occurs in first-time pregnancies in the last trimester.



PREVIOUS AND NEXT TERMS
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Fatty acid
A condition characterized by a lessened capacity for work and reduced efficiency of accomplishment, usually accompanied by a feeling of weariness and tiredness. Fatigue can be acute and come on suddenly or chronic and persist.

Fatty acid, trans
An unhealthy substance, also known as trans fat, made through the chemical process of hydrogenation of oils. Hydrogenation solidifies liquid oils and increases the shelf life and the flavor stability of oils and foods that contain them. Trans fat is found in vegetable shortenings and in some margarines, crackers, cookies, snack foods and other foods.

Fatty acids
Molecules that are long chains of lipid-carboxylic acid found in fats and oils and in cell membranes as a component of phospholipids and glycolipids.

Fatty acids,omega-3
A class of fatty acids found in fish oils, especially from salmon and other cold-water fish, that acts to lower the levels of cholesterol and LDL (low-density lipoproteins) in the blood.

Fatty alcohol
Fatty alcohol: NAD+ oxidoreductase deficiency. Clinically known as the Sjogren-Larsson syndrome, this is a genetic (inherited) disease usually characterized by a triad of findings consisting of ichthyosis (thickened fish-like skin), spastic paraplegia (spasticity of the legs) and mental retardation.

Fatty aldehyde dehydrogenase deficiency

Fatty liver of pregnancy, acute
Liver failure in late pregnancy, usually from unknown cause. Acute fatty liver of pregnancy (AFLP) typically occurs in first-time pregnancies in the last trimester.

Fauces
The throat. The word fauces is the plural of the Latin faux meaning a small passage.

Fava bean
The broad bean to which many people react adversely with an acute hemolytic anemia with sudden breakup of red blood cells (see Favism). Fava beans look like large tan lima beans. They are popular in Mediterranean and Middle Eastern cuisines, are eaten raw when very young, cooked in soups and many other dishes, and made into fava brittle (like peanut brittle) as candy. The botanical name for fava is Vicia fava. Fava is Italian for bean and refers specifically to the broad bean. Fava beans are the main commercial source of the drug L-DOPA.

Favism
A condition characterized by hemolytic anemia (breakup of red blood cells) after eating fava beans (Vicia fava) or being exposed to the pollen of the fava plant. This dangerous reaction occurs exclusively in people with a deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD), an X-linked genetic trait. However, not all G6PD-deficient families appear at risk for favism, indicating the additional need for a single autosomal (not X-linked) gene to create the susceptibility to favism of G6PD-deficient persons. The active hemolytic principle in fava beans is > likely DOPA-quinone. Differences in susceptibility to favism may be related to differences in the enzymatic system that converts L-DOPA to DOPA-quinone.

FBLN3
The gene encoding the protein known as fibulin 3.

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This dictionary contains 19186 terms.


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