|
 |
||
 |
| This glossary contains: 19186 medical terms |
 |
FBN1
|
|
FBN1The fibrillin 1 gene. This gene is mutated in Marfan syndrome, the MASS syndrome, and related disorders of connective tissue. The FBN1 gene produces a protein called fibrillin-1 which is transported out of the cell and deposited in the extracellular matrix, the intricate lattice in which cells are embedded to build tissues. In this matrix, fibrillin becomes part of small threadlike filaments called microfibrils, which in turn help build elastic fibers. Elastic fibers are essential for the function of flexible structures such as blood vessels, the lungs, and skin.
RELATED TERMS--------------------------------------
Gene
1. A unit of DNA that carries information for the biosynthesis of a specific product in the cell. 2. Ultimate unit by which inheritable characteristics are transmitted to succeeding generations in all living organisms. Genes are contained by, and arranged along the length of, the chromosome. The gene is composed of deoxyribonucleic acid (DNA). Each chromosome of each species has a definite number and arrangement of genes, which govern both the structure and metabolic functions of the cells and thus of the entire organism.
Syndrome
A grouping of signs and symptoms, based on their frequent co-occurrence, that may suggest a common underlying pathogenesis, course, familial pattern, or treatment selection.
Tissue
Biological tissue is a group of cells that perform a similar function.The study of tissues is known as histology, or, in connection with disease, histopathology.The classical tools for studying the tissues are the wax block, the tissue stain, and the optical microscope, though developments in electron microscopy, immunofluorescence, and frozen sections have all added to the sum of knowledge in the last couple of decades.
FBN1
The fibrillin 1 gene. This gene is mutated in Marfan syndrome, the MASS syndrome, and related disorders of connective tissue. The FBN1 gene produces a protein called fibrillin-1 which is transported out of the cell and deposited in the extracellular matrix, the intricate lattice in which cells are embedded to build tissues. In this matrix, fibrillin becomes part of small threadlike filaments called microfibrils, which in turn help build elastic fibers. Elastic fibers are essential for the function of flexible structures such as blood vessels, the lungs, and skin.
Protein
Any of a group of complex organic compounds which contain carbon, hydrogen, oxygen, nitrogen, and usually sulfur, the characteristic element being nitrogen. Proteins, the principal constituents of the protoplasm of all cells, are of high molecular weight and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and each protein has a unique genetically defined amino acid sequence which determines its specific shape and function. Their roles include enzymatic catalysis, transport and storage, coordinated motion, nerve impulse generation and many others.
Cell
Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.
Extracellular
Outside the cells.
Essential
1. Something that cannot be done without. 2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid. 3. Idiopathic. As in essential hypertension.
Blood
The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.
Lungs
The main respiratory organs in the chest where blood is oxygenated.
Skin
Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat).
SIMILAR TERMS--------------------------------------
PREVIOUS AND NEXT TERMS--------------------------------------
Fauces
The throat. The word fauces is the plural of the Latin faux meaning a small passage.
Fava bean
The broad bean to which many people react adversely with an acute hemolytic anemia with sudden breakup of red blood cells (see Favism). Fava beans look like large tan lima beans. They are popular in Mediterranean and Middle Eastern cuisines, are eaten raw when very young, cooked in soups and many other dishes, and made into fava brittle (like peanut brittle) as candy. The botanical name for fava is Vicia fava. Fava is Italian for bean and refers specifically to the broad bean. Fava beans are the main commercial source of the drug L-DOPA.
Favism
A condition characterized by hemolytic anemia (breakup of red blood cells) after eating fava beans (Vicia fava) or being exposed to the pollen of the fava plant. This dangerous reaction occurs exclusively in people with a deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD), an X-linked genetic trait. However, not all G6PD-deficient families appear at risk for favism, indicating the additional need for a single autosomal (not X-linked) gene to create the susceptibility to favism of G6PD-deficient persons. The active hemolytic principle in fava beans is > likely DOPA-quinone. Differences in susceptibility to favism may be related to differences in the enzymatic system that converts L-DOPA to DOPA-quinone.
FBLN3
The gene encoding the protein known as fibulin 3.
FBLN5
The gene encoding the protein known as fibulin 5.
FBN1
FCC
In medicine, familial colorectal cancer.
Fear of animals
An abnormal and persistent fear of animals termed "zoophobia. A phobia is an unreasonable fear that can cause avoidance and panic. Phobias are a relatively common type of anxiety disorder. Phobias can be treated with cognitive behavioral therapy using exposure and fear reduction techniques. In many cases, anti-anxiety or anti-depressant medication proves helpful, especially during the early stages of therapy. "Zoophobia" encompasses fears of specific types of animals such as of spiders (arachnophobia), birds (ornithophobia), bees (apiphobia), etc. It is literally a zoo-ful of beastly phobias.
Fear of bacteria
An abnormal and persistent fear of bacilli (bacteria). A phobia is an unreasonable sort of fear that can cause avoidance and panic. Phobias are a relatively common type of anxiety disorder. Phobias can be treated with cognitive behavioral therapy using exposure and fear reduction techniques. In many cases, anti- anxiety or anti-depressant medication proves helpful, especially during the early stages of therapy. Another term for bacillophobia is bacteriaphobia.
Fear of bees
An abnormal and persistent fear of bees. A phobia can cause avoidance and panic. Phobias are a relatively common type of anxiety disorder. Phobias can be treated with cognitive behavioral therapy using exposure and fear reduction techniques. In many cases, anti-anxiety or anti-depressant medication proves helpful, especially during the early stages of therapy.
Fear of being buried alive
An abnormal and persistent fear of being buried alive is called taphephobia.A phobia is an unreasonable sort of fear that can cause avoidance and panic. Phobias are a relatively common type of anxiety disorder. Phobias can be treated with cognitive behavioral therapy using exposure and fear reduction techniques. In many cases, anti-anxiety or anti-depressant medication proves helpful, especially during the early stages of therapy.
RELATED TERMS--------------------------------------
Gene
1. A unit of DNA that carries information for the biosynthesis of a specific product in the cell. 2. Ultimate unit by which inheritable characteristics are transmitted to succeeding generations in all living organisms. Genes are contained by, and arranged along the length of, the chromosome. The gene is composed of deoxyribonucleic acid (DNA). Each chromosome of each species has a definite number and arrangement of genes, which govern both the structure and metabolic functions of the cells and thus of the entire organism.
Syndrome
A grouping of signs and symptoms, based on their frequent co-occurrence, that may suggest a common underlying pathogenesis, course, familial pattern, or treatment selection.
Tissue
Biological tissue is a group of cells that perform a similar function.The study of tissues is known as histology, or, in connection with disease, histopathology.The classical tools for studying the tissues are the wax block, the tissue stain, and the optical microscope, though developments in electron microscopy, immunofluorescence, and frozen sections have all added to the sum of knowledge in the last couple of decades.
FBN1
The fibrillin 1 gene. This gene is mutated in Marfan syndrome, the MASS syndrome, and related disorders of connective tissue. The FBN1 gene produces a protein called fibrillin-1 which is transported out of the cell and deposited in the extracellular matrix, the intricate lattice in which cells are embedded to build tissues. In this matrix, fibrillin becomes part of small threadlike filaments called microfibrils, which in turn help build elastic fibers. Elastic fibers are essential for the function of flexible structures such as blood vessels, the lungs, and skin.
Protein
Any of a group of complex organic compounds which contain carbon, hydrogen, oxygen, nitrogen, and usually sulfur, the characteristic element being nitrogen. Proteins, the principal constituents of the protoplasm of all cells, are of high molecular weight and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and each protein has a unique genetically defined amino acid sequence which determines its specific shape and function. Their roles include enzymatic catalysis, transport and storage, coordinated motion, nerve impulse generation and many others.
Cell
Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.
Extracellular
Outside the cells.
Essential
1. Something that cannot be done without. 2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid. 3. Idiopathic. As in essential hypertension.
Blood
The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.
Lungs
The main respiratory organs in the chest where blood is oxygenated.
Skin
Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat).
SIMILAR TERMS--------------------------------------
PREVIOUS AND NEXT TERMS--------------------------------------
Fauces
The throat. The word fauces is the plural of the Latin faux meaning a small passage.
Fava bean
The broad bean to which many people react adversely with an acute hemolytic anemia with sudden breakup of red blood cells (see Favism). Fava beans look like large tan lima beans. They are popular in Mediterranean and Middle Eastern cuisines, are eaten raw when very young, cooked in soups and many other dishes, and made into fava brittle (like peanut brittle) as candy. The botanical name for fava is Vicia fava. Fava is Italian for bean and refers specifically to the broad bean. Fava beans are the main commercial source of the drug L-DOPA.
Favism
A condition characterized by hemolytic anemia (breakup of red blood cells) after eating fava beans (Vicia fava) or being exposed to the pollen of the fava plant. This dangerous reaction occurs exclusively in people with a deficiency of the enzyme glucose-6-phosphate dehydrogenase (G6PD), an X-linked genetic trait. However, not all G6PD-deficient families appear at risk for favism, indicating the additional need for a single autosomal (not X-linked) gene to create the susceptibility to favism of G6PD-deficient persons. The active hemolytic principle in fava beans is > likely DOPA-quinone. Differences in susceptibility to favism may be related to differences in the enzymatic system that converts L-DOPA to DOPA-quinone.
FBLN3
The gene encoding the protein known as fibulin 3.
FBLN5
The gene encoding the protein known as fibulin 5.
FBN1
FCC
In medicine, familial colorectal cancer.
Fear of animals
An abnormal and persistent fear of animals termed "zoophobia. A phobia is an unreasonable fear that can cause avoidance and panic. Phobias are a relatively common type of anxiety disorder. Phobias can be treated with cognitive behavioral therapy using exposure and fear reduction techniques. In many cases, anti-anxiety or anti-depressant medication proves helpful, especially during the early stages of therapy. "Zoophobia" encompasses fears of specific types of animals such as of spiders (arachnophobia), birds (ornithophobia), bees (apiphobia), etc. It is literally a zoo-ful of beastly phobias.
Fear of bacteria
An abnormal and persistent fear of bacilli (bacteria). A phobia is an unreasonable sort of fear that can cause avoidance and panic. Phobias are a relatively common type of anxiety disorder. Phobias can be treated with cognitive behavioral therapy using exposure and fear reduction techniques. In many cases, anti- anxiety or anti-depressant medication proves helpful, especially during the early stages of therapy. Another term for bacillophobia is bacteriaphobia.
Fear of bees
An abnormal and persistent fear of bees. A phobia can cause avoidance and panic. Phobias are a relatively common type of anxiety disorder. Phobias can be treated with cognitive behavioral therapy using exposure and fear reduction techniques. In many cases, anti-anxiety or anti-depressant medication proves helpful, especially during the early stages of therapy.
Fear of being buried alive
An abnormal and persistent fear of being buried alive is called taphephobia.A phobia is an unreasonable sort of fear that can cause avoidance and panic. Phobias are a relatively common type of anxiety disorder. Phobias can be treated with cognitive behavioral therapy using exposure and fear reduction techniques. In many cases, anti-anxiety or anti-depressant medication proves helpful, especially during the early stages of therapy.
We thank you for using the Medical Glossary to search for FBN1. If you have a better definition for FBN1 than the one presented here, please let us know by making use of the suggest a term option. This definition of FBN1 may be disputed by other professionals. Our attempt is to provide easy definitions on FBN1 and any other medical topic for the public at large.
This dictionary contains 19186 terms.
|
|