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Exemestane
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ExemestaneAn oral antiestrogen. Exemestane inhibits the enzyme aromatase in the adrenal glands that produces the estrogens (estradiol and estrone) and thereby lowers their levels.
RELATED TERMS--------------------------------------
Oral
Of or involving the mouth or mouth region or the surface on which the mouth is located.
Antiestrogen
A substance that can prevent the full expression of estrogen. Antiestrogens act by exerting antagonistic effects on target tissues (androgens and progestogens act in this way) or by competing with estrogens for access to receptor sites located on the cell surface.
Exemestane
An oral antiestrogen. Exemestane inhibits the enzyme aromatase in the adrenal glands that produces the estrogens (estradiol and estrone) and thereby lowers their levels.
Enzyme
A cellular protein whose shape allows it to hold together several other molecules in close proximity to each other. In this way, enzymes are able to induce chemical reactions in other substances with little expenditure of energy and without being changed themselves. Basically, an enzyme acts as a catalyst.
Aromatase
An enzyme involved in the production of estrogen that acts by catalyzing the conversion of testosterone (an androgen) to estradiol (an estrogen). Aromatase is located in estrogen-producing cells in the adrenal glands, ovaries, placenta, testicles, adipose (fat) tissue, and brain. The growth of some breast cancers is promoted by estrogens. For example, the drug letrozole (brand name: Femara) is an antiestrogen sometimes used to treat such estrogen-dependent tumors. The drug acts by inhibiting the enzyme aromatase which lowers the level of the estrogen, estradiol.
Estrogens
A group of three steroid hormones that convey female characteristics and control fertilization. The production of estrogen is stimulated by follicle-stimulating hormone (FSH), which uses cyclic AMP as its second messenger.
SIMILAR TERMS--------------------------------------
Exempla Lutheran Medical Center
Exempla Lutheran Medical Center is a hospital in Wheat Ridge, Colorado (USA).
Exemplar
A person who becomes a pattern or model for oneself.
PREVIOUS AND NEXT TERMS--------------------------------------
Excision
1. Surgical removal, as in the excision of a tumor. 2. The removal as if by surgery, as in base excision repair.
Excisional
Pertaining to the act of excision, of removal by surgery. An excisional biopsy is one in which the lesion is removed by the biopsy.
Excisional biopsy
A biopsy in which an entire biopsy in which an entire lesion, is removed. A excisional biopsy is in contrast to an incisional biopsy in which only a sample of tissue is cut into (incised) and removed.
Exclamation point hair
Exclamation point hair is a key diagnostic finding in a disorder called alopecia areata. Alopecia areata is patchy baldness (alopecia means baldness and areata means occurring in patches) which typically begins with patchy hair loss on the scalp and sometimes progresses to complete baldness and even loss of body hair. The hair loss tends to be rather rapid and asymmetrical and is different than male pattern baldness.Alopecia areata affects both males and females. It tends to occur most often in children and young adults but older individuals can also be affected.The most common pattern of alopecia areata is one or more spots of hair loss on the scalp. There is also a form with more generalized thinning. When all of the scalp hair is lost, it is called alopecia totalis. Loss of all of the hairs on the body is called alopecia universalis.
Excrescence
An abnormal outgrowth as, for example, a wart.
Exemestane
Exercise test
A test (sometimes called the treadmill test or exercise treadmill test) in which a continuous electrocardiogram (ECG or EKG) recording of the heart is made as the patient performs increasing levels of exercise on the treadmill which is tilted to produce the effect of going up a small hill. The patient can stop the test at any time, if necessary. Afterwards the patient has heart and blood pressure checked. There is very little risk in taking the test in healthy persons -- no more than if a person walks fast or jogs up a big hill. Medical professionals should be present in case something unusual happens during the test. The exercise test screens for the presence of narrowed coronary arteries that can limit the supply of oxygenated blood to the heart muscle during exercise. The test also detects abnormal heart rhythms (arrhythmias).
Exercise treadmill
Exercise on a treadmill, a machine with a moving strip on which one walks without moving forward. A treadmill was originally a wide wheel turned by the weight of people climbing on steps around its edge, used in the past to provide power for machines or as a punishment in prisons.
Exercise treadmill test
A test (sometimes simply called a treadmill test or exercise test) in which a continuous electrocardiogram (ECG or EKG) recording of the heart is made as the patient performs increasing levels of exercise on the treadmill which is tilted to produce the effect of going up a small hill. The patient can stop the test at any time, if necessary. Afterwards the patient has heart and blood pressure checked.
Exercise, isometric
Exercise involving muscular contractions without movement of the involved parts of the body. Isometric exercise is one method of muscular exercise. In contrast, isotonic exercise occurs when a contracting muscle shortens against a constant load, as when lifting a weight.
Exercise, isotonic
Exercise when a contracting muscle shortens against a constant load, as when lifting a weight. Isometric exercise is one method of muscular exercise. In contrast, isotonic exercise is when muscular contractions occur without movement of the involved parts of the body.
RELATED TERMS--------------------------------------
Oral
Of or involving the mouth or mouth region or the surface on which the mouth is located.
Antiestrogen
A substance that can prevent the full expression of estrogen. Antiestrogens act by exerting antagonistic effects on target tissues (androgens and progestogens act in this way) or by competing with estrogens for access to receptor sites located on the cell surface.
Exemestane
An oral antiestrogen. Exemestane inhibits the enzyme aromatase in the adrenal glands that produces the estrogens (estradiol and estrone) and thereby lowers their levels.
Enzyme
A cellular protein whose shape allows it to hold together several other molecules in close proximity to each other. In this way, enzymes are able to induce chemical reactions in other substances with little expenditure of energy and without being changed themselves. Basically, an enzyme acts as a catalyst.
Aromatase
An enzyme involved in the production of estrogen that acts by catalyzing the conversion of testosterone (an androgen) to estradiol (an estrogen). Aromatase is located in estrogen-producing cells in the adrenal glands, ovaries, placenta, testicles, adipose (fat) tissue, and brain. The growth of some breast cancers is promoted by estrogens. For example, the drug letrozole (brand name: Femara) is an antiestrogen sometimes used to treat such estrogen-dependent tumors. The drug acts by inhibiting the enzyme aromatase which lowers the level of the estrogen, estradiol.
Estrogens
A group of three steroid hormones that convey female characteristics and control fertilization. The production of estrogen is stimulated by follicle-stimulating hormone (FSH), which uses cyclic AMP as its second messenger.
SIMILAR TERMS--------------------------------------
Exempla Lutheran Medical Center
Exempla Lutheran Medical Center is a hospital in Wheat Ridge, Colorado (USA).
Exemplar
A person who becomes a pattern or model for oneself.
PREVIOUS AND NEXT TERMS--------------------------------------
Excision
1. Surgical removal, as in the excision of a tumor. 2. The removal as if by surgery, as in base excision repair.
Excisional
Pertaining to the act of excision, of removal by surgery. An excisional biopsy is one in which the lesion is removed by the biopsy.
Excisional biopsy
A biopsy in which an entire biopsy in which an entire lesion, is removed. A excisional biopsy is in contrast to an incisional biopsy in which only a sample of tissue is cut into (incised) and removed.
Exclamation point hair
Exclamation point hair is a key diagnostic finding in a disorder called alopecia areata. Alopecia areata is patchy baldness (alopecia means baldness and areata means occurring in patches) which typically begins with patchy hair loss on the scalp and sometimes progresses to complete baldness and even loss of body hair. The hair loss tends to be rather rapid and asymmetrical and is different than male pattern baldness.Alopecia areata affects both males and females. It tends to occur most often in children and young adults but older individuals can also be affected.The most common pattern of alopecia areata is one or more spots of hair loss on the scalp. There is also a form with more generalized thinning. When all of the scalp hair is lost, it is called alopecia totalis. Loss of all of the hairs on the body is called alopecia universalis.
Excrescence
An abnormal outgrowth as, for example, a wart.
Exemestane
Exercise test
A test (sometimes called the treadmill test or exercise treadmill test) in which a continuous electrocardiogram (ECG or EKG) recording of the heart is made as the patient performs increasing levels of exercise on the treadmill which is tilted to produce the effect of going up a small hill. The patient can stop the test at any time, if necessary. Afterwards the patient has heart and blood pressure checked. There is very little risk in taking the test in healthy persons -- no more than if a person walks fast or jogs up a big hill. Medical professionals should be present in case something unusual happens during the test. The exercise test screens for the presence of narrowed coronary arteries that can limit the supply of oxygenated blood to the heart muscle during exercise. The test also detects abnormal heart rhythms (arrhythmias).
Exercise treadmill
Exercise on a treadmill, a machine with a moving strip on which one walks without moving forward. A treadmill was originally a wide wheel turned by the weight of people climbing on steps around its edge, used in the past to provide power for machines or as a punishment in prisons.
Exercise treadmill test
A test (sometimes simply called a treadmill test or exercise test) in which a continuous electrocardiogram (ECG or EKG) recording of the heart is made as the patient performs increasing levels of exercise on the treadmill which is tilted to produce the effect of going up a small hill. The patient can stop the test at any time, if necessary. Afterwards the patient has heart and blood pressure checked.
Exercise, isometric
Exercise involving muscular contractions without movement of the involved parts of the body. Isometric exercise is one method of muscular exercise. In contrast, isotonic exercise occurs when a contracting muscle shortens against a constant load, as when lifting a weight.
Exercise, isotonic
Exercise when a contracting muscle shortens against a constant load, as when lifting a weight. Isometric exercise is one method of muscular exercise. In contrast, isotonic exercise is when muscular contractions occur without movement of the involved parts of the body.
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This dictionary contains 19186 terms.
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