Medical Glossary

This glossary contains:
19186
medical terms

Embryoid bodies (EBs)




Embryoid bodies (EBs)

Irregularly shaped clumps of cellular structures that arise when embryonic stem cells or embryonic germ cells are cultured. Embryoid bodies usually contain tissue from all three of the germ layers: endoderm, mesoderm, and ectoderm. Embryoid bodies are not part of normal development and occur only in vitro.

RELATED TERMS
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Embryonic
Undeveloped, related to the embryo.

Germ
A disease-causing microorganism.

Tissue
Biological tissue is a group of cells that perform a similar function.The study of tissues is known as histology, or, in connection with disease, histopathology.The classical tools for studying the tissues are the wax block, the tissue stain, and the optical microscope, though developments in electron microscopy, immunofluorescence, and frozen sections have all added to the sum of knowledge in the last couple of decades.

Endoderm
One of the three primary germ cell layers -- the other two are the mesoderm and ectoderm -- in the very early embryo. The endoderm is the innermost of the three layers. It differentiates to give rise first to the embryonic gut and then to the linings of respiratory and digestive tracts and the liver and pancreas.

Mesoderm
The middle layer of cells in an embryo, from which the muscular, skeletal, vascular, connective etc. tissues develop.

Ectoderm
One of the three primary germ cell layers (the other two being the mesoderm and endoderm) that make up the very early embryo. The ectoderm is the outermost of the three layers. It differentiates to give rise to many important tissues and structures including the outer layer of the skin and its appendages (the sweat glands, hair, and nails), the teeth, the lens of the eye, parts of the inner ear, the nerves, brain, and spinal cord. This much is classic human embryology. Stem cell research, however, has shown that some cells within ectodermal structures retain their ability to differentiate into other tissues. For example, some cells in brain (ectoderm) can become bone marrow (mesoderm).

Development
The process of growth and differentiation.



SIMILAR TERMS
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Embreeville Center
The Embreeville Center is a hospital in Coatesville, Pennsylvania, United States.

Embryo
The early stages of development before an organism becomes self supporting.

Embryo biopsy
An experimental test for genetic defects in embryos before they are implanted using IVF (in vitro fertilization).

Embryo splitting
Separation of an early-stage embryo into two or more embryos with identical genetic makeup, essentially creating identical twins or higher multiples (triplets, quadruplets, etc.).

Embryo transfer
An assisted reproductive technology in which an already fertilized egg is inserted into a woman's uterus to help her get pregnant.

Embryonal carcinoma
A malignant germ cell tumor that occurs most often in the testes and accounts for about 40% of testicular tumors. Under the microscope, these tumors may resemble tissues of early embryos. This type of tumor can grow rapidly and spread outside the testicle. Embryonal carcinoma of the ovary is rare. It usually occurs before the age of 30 and is often prepubertal.

Embryonic
Undeveloped, related to the embryo.

Embryonic germ cells
Pluripotent stem cell lines that migrate, during early development, to the future gonads to form the progenitors of egg or sperm cells. The properties of EG cells are similar to those of embryonic stem cells, but may differ in the DNA methylation of some imprinted regions.

Embryonic hemoglobin
Hemoglobin E, the normal embryonic hemoglobin, the main type of hemoglobin found in the human embryo. The E stands for embryonic and also for epsilon, the chain unique to embryonic hemoglobin (which was originally known as Gower-2).

Embryonic stem cell lines
Populations of dividing cells established from embryonic stem cells and cultured in the laboratory. Within embryonic cell lines are cells that can produce more embryonic stem cells or, under conditions of differentiation, give rise to collections of cells that include most or all cell types that can be found in a postimplantation embryo, fetus, or developed organism.

Embryonic stem cells
Primitive (undifferentiated ) cultured cells from the embryo that have the potential to become a wide variety of specialized cell types, (that is, are pluripotent). They are derived from the inner cell mass of the blastocyst. Embryonic stem cells are not embryos; by themselves, they cannot produce the necessary cell types, such as trophectoderm cells, in an organized fashion so as to give rise to a complete organism.



PREVIOUS AND NEXT TERMS
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External urethral sphincter muscle
A voluntary and involuntary ring-like band of muscle fibers that you voluntarily contract when you want to stop urinating.

Extrinsic asthma
Asthma that is triggered by an allergic reaction, usually to something that is inhaled.

Extracorporeal shock wave lithotripsy (ESWL)
A method of breaking up bile stones and gallstones. Uses a specialized tool and shock waves.

Egg
The mature female reproductive cell.

Embryo splitting
Separation of an early-stage embryo into two or more embryos with identical genetic makeup, essentially creating identical twins or higher multiples (triplets, quadruplets, etc.).

Embryoid bodies (EBs)

Embryonic germ cells
Pluripotent stem cell lines that migrate, during early development, to the future gonads to form the progenitors of egg or sperm cells. The properties of EG cells are similar to those of embryonic stem cells, but may differ in the DNA methylation of some imprinted regions.

Embryonic stem cells
Primitive (undifferentiated ) cultured cells from the embryo that have the potential to become a wide variety of specialized cell types, (that is, are pluripotent). They are derived from the inner cell mass of the blastocyst. Embryonic stem cells are not embryos; by themselves, they cannot produce the necessary cell types, such as trophectoderm cells, in an organized fashion so as to give rise to a complete organism.

Embryonic stem cell lines
Populations of dividing cells established from embryonic stem cells and cultured in the laboratory. Within embryonic cell lines are cells that can produce more embryonic stem cells or, under conditions of differentiation, give rise to collections of cells that include most or all cell types that can be found in a postimplantation embryo, fetus, or developed organism.

Epigenetic effects
Changes in gene expression that occur without changing the DNA sequence of a gene; for example, in the epigenetic effect called genomic imprinting, chemical molecules called methyl groups attach to DNA and "turn off" the gene's expression.

Extraembryonic tissues
Intrauterine tissues derived from the zygote that support the embryo(for example, the placenta, the umbilical cord, and membranes such as the amniotic sac).

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This dictionary contains 19186 terms.







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