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EPO (erythropoietin)
EPO (erythropoietin)A hormone produced by the kidney that promotes the formation of red blood cells in the bone marrow. EPO is a glycoprotein (a protein with a sugar attached to it). Human EPO has a molecular weight of 34,000. The kidney cells that make EPO are specialized and are sensitive to low oxygen levels in the blood. These cells release EPO when the oxygen level is low in the kidney. EPO then stimulates the bone marrow to produce more red cells and thereby increase the oxygen-carrying capacity of the blood. RELATED TERMS-------------------------------------- Hormone A chemical substance formed in the body that is carried in the bloodstream to affect another part of the body; an example is thyroid hormone, produced by the thyroid gland in the neck, which affects growth, temperature regulation, metabolic rate, and other body functions. Kidney One of the paired organs that excrete urine. The kidneys are bean-shaped organs (about 11 cm long, 5 cm wide, and 3 cm thick) lying on either side of the vertebral column, posterior to the peritoneum, about opposite the twelfth thoracic and first three lumbar vertebrae. Blood The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues. Bone Bone refers either to a hardened connective tissue or to one of the individual structures, or organs, into which it is formed, found in many animals. Bones support body structures, protect internal organs, and (in conjunction with muscles) facilitate movement; are also involved with cell formation, calcium metabolism, and mineral storage. The bones of an animal are, collectively, known as the skeleton. Marrow The tissue which fills the cavities of most bones; the medulla. In the larger cavities it is commonly very fatty, but in the smaller cavities it is much less fatty, and red or reddish in color. Protein Any of a group of complex organic compounds which contain carbon, hydrogen, oxygen, nitrogen, and usually sulfur, the characteristic element being nitrogen. Proteins, the principal constituents of the protoplasm of all cells, are of high molecular weight and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and each protein has a unique genetically defined amino acid sequence which determines its specific shape and function. Their roles include enzymatic catalysis, transport and storage, coordinated motion, nerve impulse generation and many others. Sugar A class of carbohydrates that taste sweet. Sugar is a quick and easy fuel for the body to use. Types of sugar are lactose, glucose, fructose, and sucrose. Molecular Refers to the basic building blocks of the genetic material, such as DNA, genes and the other chemicals involved with the functioning of genes. Oxygen A chemical element essential for sustaining life. SIMILAR TERMS-------------------------------------- EPO test A test of the hormone EPO (erythropoietin) in blood. The EPO level can indicate bone marrow disorders, kidney disease, or EPO abuse. PREVIOUS AND NEXT TERMS-------------------------------------- Epispadias Congenital (at birth) malformation in which the opening of the urethra (from whence comes the urinary stream) is on the dorsum (topside) of the penis. Hypospadias is the corresponding malformation in which the opening of the urethra is on the ventral surface (underside) of the penis. Epistaxis, treatment of To stop epistaxis (a nosebleed), you should: 1. Pinch all the soft parts of the nose together between your thumb and index finger. 2. Press firmly toward the face - compressing the pinched parts of the nose against the bones of the face. 3. Hold the nose for at least 5 minutes (timed by the clock). Repeat as necessary until the nose has stopped bleeding. 4. Sit quietly, keeping the head higher than the level of the heart; that is, sit up or lie with the head elevated. Do not lay flat or put your head between your legs. 5. Apply ice (crushed in a plastic bag or washcloth) to nose and cheeks. Epistemic Cognitive. Pertaining to cognition, the process of knowing and, more precisely, the process of being aware, knowing, thinking, learning and judging. Epithelial basement corneal dystrophy A disorder in which the cornea (the normally clear front window of the eye) shows grayish fingerprint lines, geographic map-like lines, and dots (or microcysts) on examination with a slit-lamp that focuses a high intensity light beam as a slit while the examiner looks at the front of the eye through a magnifying scope. Epithelial carcinoma Cancer that begins in the cells that line an organ. EPO (erythropoietin) EPO test A test of the hormone EPO (erythropoietin) in blood. The EPO level can indicate bone marrow disorders, kidney disease, or EPO abuse. EPR Abbreviation for Electrophrenic respiration. Also known as diaphragm pacing. EPS Stands for ElectroPhysiologic Study, a test of the electrical conduction system of the heart (the system that generates the heart beat). Epsom salt Magnesium sulfate. Known as Epsom salt because it was originally extracted from the mineral-rich water of Epsom (England). Epstein-Barr virus A virus, abbreviated EBV, best known as the cause of infectious mononucleosis ("mono"). Infection with EBV is characterized by fatigue and general malaise. Infection with EBV is fairly common and is usually a transient and minor thing. However, in some individuals EBV can trigger chronic illness, including immune and lymphoproliferative syndromes. It is a particular danger to people with compromised immune systems, such as from AIDS. EBV was at one time believed to be the cause of the chronic fatigue syndrome, but chronic infection with this virus actually produces a separate (if similar) disorder. We thank you for using the Medical Glossary to search for EPO (erythropoietin). If you have a better definition for EPO (erythropoietin) than the one presented here, please let us know by making use of the suggest a term option. This definition of EPO (erythropoietin) may be disputed by other professionals. Our attempt is to provide easy definitions on EPO (erythropoietin) and any other medical topic for the public at large.
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