|
 |
||
 |
| This glossary contains: 19186 medical terms |
 |
Donor lymphocyte infusion
|
|
Donor lymphocyte infusion(DLI) A cancer treatment in which lymphocytes from a bone marrow donor are infused into the person who received the original bone marrow transplant. The goal of donor lymphocyte infusion is to induce a remission of the cancer by a process called the graft-versus-tumor (GVT) effect. Donor lymphocyte infusion is basically meant to boost the GVT effect. The donor lymphocytes, which are T cells, attack and kill residual cancer cells. That is the strategy. Donor lymphocyte infusion has mainly been used to treat relapsed chronic myelogenous leukemia (CML). Patients with relapsed acute leukemia, chronic lymphocytic leukemia (CLL), myelodysplasia (MDS), Hodgkin disease, non-Hodgkin lymphoma (NHL), and multiple myeloma have also been treated by donor leukocyte infusion.
RELATED TERMS--------------------------------------
Cancer
Any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream.
Bone
Bone refers either to a hardened connective tissue or to one of the individual structures, or organs, into which it is formed, found in many animals. Bones support body structures, protect internal organs, and (in conjunction with muscles) facilitate movement; are also involved with cell formation, calcium metabolism, and mineral storage. The bones of an animal are, collectively, known as the skeleton.
Marrow
The tissue which fills the cavities of most bones; the medulla. In the larger cavities it is commonly very fatty, but in the smaller cavities it is much less fatty, and red or reddish in color.
Donor
A person who gives an organ, tissue or blood to another person. A compatible donor is a person who has the same tissue and blood types as the person who receives the organ, tissue or blood.
Lymphocyte
White blood cell. Lymphocytes have a number of roles in the immune system, including antibody production, attacking and destroying cancer cells, and producing substances that kill cancer cells.
Remission
Improvement of the symptoms of a disease.
Residual
Remaining tumor.
Chronic
Ongoing or recurring. Chronic medical conditions include diabetes, epilepsy, and chronic fatigue syndrome.
Leukemia
Cancer of white blood cells. Acute leukemias are characterized by the presence of "blasts," which are immature white blood cells. Large quantities of blasts generally overgrow the bone marrow, leaving very little space for normal bone marrow cells. This type generally requires immediate treatment. Chronic leukemias are those characterized by a large and uncontrolled growth of more mature white blood cells. These types of leukemias tend not to progress as rapidly, and treatment is often milder than that of acute leukemias.
Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.
Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.
Lymphoma
Cancer of the lymphoid tissues. Lymphomas are often described as being large cell or small cell types, cleaved or non-cleaved, or diffuse or nodular. The different types often have different prognoses. Lymphomas can also be referred to by the organs where they are active, such as CNS lymphomas, which are in the central nervous system, and GI lymphomas, which are in the gastrointestinal tract. The types of lymphomas most commonly associated with HIV infection are called non-Hodgkin's lymphomas or B cell lymphomas. In these types of cancers, certain cells of the lymphatic.
Myeloma
A tumour of plasma cells, generally secreting a single species of immunoglobulin.
Leukocyte
White blood cell.
SIMILAR TERMS--------------------------------------
Donor
A person who gives an organ, tissue or blood to another person. A compatible donor is a person who has the same tissue and blood types as the person who receives the organ, tissue or blood.
Donor insemination
Or Artificial insemination (AI. Deposition of sperm from a male donor inside a female reproductive tract for the purpose of achieving pregnancy.
Donor, universal
A person who is type O in the ABO blood group system and can donate blood to all recipients.
Donostiako Ospitaletegia
Donostiako Ospitaletegia is a hospital in San Sebastian, Basque Country (Spain).
PREVIOUS AND NEXT TERMS--------------------------------------
DOB
Abbreviation standing for the date of birth.
DOC
1. Acronym for "daily on call." 2. Deoxycorticosterone.
Docosahexaenoic acid
DHA. An essential fatty acid, thought to be important to the development of infants, particularly as regards their eyes and brain. DHA is present in breast milk and has been added to some infant formulas. Postnatal DHA may improve vision and some cognitive functions in infants and toddlers. DHA is an omega-3, polyunsaturated, 22-carbon fatty acid. It is present in abundance in certain fish (such as tuna and bluefish) and marine animal oils.
Dol
A unit of measurement of pain. The term dol was invented by James Hardy and his research colleagues Herbert Wolff and Helen Goodell at Cornell University where from 1950 to 1959, they carried out pioneering experiments on pain. Hasrdy, Wolff and Goodell used precisely calibrated radiant heat directed to the foreheads or hands of trained experimental subjects. They asked the subjects to report each "just noticeable difference" in the intensity of pain they experienced, and graphed their responses on the "dol" scale, in which one dol equals two "just noticeable differences." The graphs showed the effectiveness of different analgesics in relieving the pain, and the physiologic responses with different intensities of pain. From the Latin word for pain, dolor.
Dominant
A genetic trait is considered dominant if it is expressed in a person who has only one copy of that gene. (In genetic terms, a dominant trait is one that is phenotypically expressed in heterozygotes). A dominant trait is opposed to a recessive trait which is expressed only when two copies of the gene are present. (In genetic terms, a recessive trait is one that is phenotypically expressed only in homozygotes).
Donor lymphocyte infusion
Donor, universal
A person who is type O in the ABO blood group system and can donate blood to all recipients.
Dopa
A precursor (forerunner) of dopamine, a key neurotransmitter (messenger) in the brain. Dopa is used in the treatment of Parkinson disease. Parkinson disease is believed to be related to low levels of dopamine in certain parts of the brain. When dopa is taken by mouth, it crosses through the blood-brain barrier. Once it has crossed from the bloodstream into the brain, it is converted to dopamine. The resulting increase in dopamine concentrations in the brain is thought to improve nerve conduction and to assist in lessening the movement disorders in Parkinson disease.
Dopa-responsive dystonia (DRD)
A condition that typically begins in childhood or adolescence with progressive difficulty in walking and, in some cases, spasticity and can be successfully treated with drugs. Segawa dystonia is an important variant of DRD. In Segawa dystonia, the symptoms fluctuate during the day from relative mobility in the morning to increasing disability in the afternoon and evening and after exercise. DRD may not only be rare but also rarely diagnosed since it mimics some forms of cerebral palsy.
Dorian Gray effect
Sudden aging, an abrupt change from seeming youthfulness to the reality and ravages of age, as can occur naturally or when the effects of plastic surgery and Botox treatments wear off.
Dorsum
The back or posterior side of a structure. "Dorsum" is the Latin word for the back. Something pertaining to the dorsum is dorsal. The dorsal surface of the hand is the back of the hand, the side opposite the palm. The dorsal surface of the foot is the back of the foot, the side opposite the sole. The dorsal vertebrae are the thoracic vertebrae; they form part of the back. The dorsal roots of the spinal nerves are the back roots, the posterior roots.
RELATED TERMS--------------------------------------
Cancer
Any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream.
Bone
Bone refers either to a hardened connective tissue or to one of the individual structures, or organs, into which it is formed, found in many animals. Bones support body structures, protect internal organs, and (in conjunction with muscles) facilitate movement; are also involved with cell formation, calcium metabolism, and mineral storage. The bones of an animal are, collectively, known as the skeleton.
Marrow
The tissue which fills the cavities of most bones; the medulla. In the larger cavities it is commonly very fatty, but in the smaller cavities it is much less fatty, and red or reddish in color.
Donor
A person who gives an organ, tissue or blood to another person. A compatible donor is a person who has the same tissue and blood types as the person who receives the organ, tissue or blood.
Lymphocyte
White blood cell. Lymphocytes have a number of roles in the immune system, including antibody production, attacking and destroying cancer cells, and producing substances that kill cancer cells.
Remission
Improvement of the symptoms of a disease.
Residual
Remaining tumor.
Chronic
Ongoing or recurring. Chronic medical conditions include diabetes, epilepsy, and chronic fatigue syndrome.
Leukemia
Cancer of white blood cells. Acute leukemias are characterized by the presence of "blasts," which are immature white blood cells. Large quantities of blasts generally overgrow the bone marrow, leaving very little space for normal bone marrow cells. This type generally requires immediate treatment. Chronic leukemias are those characterized by a large and uncontrolled growth of more mature white blood cells. These types of leukemias tend not to progress as rapidly, and treatment is often milder than that of acute leukemias.
Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.
Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.
Lymphoma
Cancer of the lymphoid tissues. Lymphomas are often described as being large cell or small cell types, cleaved or non-cleaved, or diffuse or nodular. The different types often have different prognoses. Lymphomas can also be referred to by the organs where they are active, such as CNS lymphomas, which are in the central nervous system, and GI lymphomas, which are in the gastrointestinal tract. The types of lymphomas most commonly associated with HIV infection are called non-Hodgkin's lymphomas or B cell lymphomas. In these types of cancers, certain cells of the lymphatic.
Myeloma
A tumour of plasma cells, generally secreting a single species of immunoglobulin.
Leukocyte
White blood cell.
SIMILAR TERMS--------------------------------------
Donor
A person who gives an organ, tissue or blood to another person. A compatible donor is a person who has the same tissue and blood types as the person who receives the organ, tissue or blood.
Donor insemination
Or Artificial insemination (AI. Deposition of sperm from a male donor inside a female reproductive tract for the purpose of achieving pregnancy.
Donor, universal
A person who is type O in the ABO blood group system and can donate blood to all recipients.
Donostiako Ospitaletegia
Donostiako Ospitaletegia is a hospital in San Sebastian, Basque Country (Spain).
PREVIOUS AND NEXT TERMS--------------------------------------
DOB
Abbreviation standing for the date of birth.
DOC
1. Acronym for "daily on call." 2. Deoxycorticosterone.
Docosahexaenoic acid
DHA. An essential fatty acid, thought to be important to the development of infants, particularly as regards their eyes and brain. DHA is present in breast milk and has been added to some infant formulas. Postnatal DHA may improve vision and some cognitive functions in infants and toddlers. DHA is an omega-3, polyunsaturated, 22-carbon fatty acid. It is present in abundance in certain fish (such as tuna and bluefish) and marine animal oils.
Dol
A unit of measurement of pain. The term dol was invented by James Hardy and his research colleagues Herbert Wolff and Helen Goodell at Cornell University where from 1950 to 1959, they carried out pioneering experiments on pain. Hasrdy, Wolff and Goodell used precisely calibrated radiant heat directed to the foreheads or hands of trained experimental subjects. They asked the subjects to report each "just noticeable difference" in the intensity of pain they experienced, and graphed their responses on the "dol" scale, in which one dol equals two "just noticeable differences." The graphs showed the effectiveness of different analgesics in relieving the pain, and the physiologic responses with different intensities of pain. From the Latin word for pain, dolor.
Dominant
A genetic trait is considered dominant if it is expressed in a person who has only one copy of that gene. (In genetic terms, a dominant trait is one that is phenotypically expressed in heterozygotes). A dominant trait is opposed to a recessive trait which is expressed only when two copies of the gene are present. (In genetic terms, a recessive trait is one that is phenotypically expressed only in homozygotes).
Donor lymphocyte infusion
Donor, universal
A person who is type O in the ABO blood group system and can donate blood to all recipients.
Dopa
A precursor (forerunner) of dopamine, a key neurotransmitter (messenger) in the brain. Dopa is used in the treatment of Parkinson disease. Parkinson disease is believed to be related to low levels of dopamine in certain parts of the brain. When dopa is taken by mouth, it crosses through the blood-brain barrier. Once it has crossed from the bloodstream into the brain, it is converted to dopamine. The resulting increase in dopamine concentrations in the brain is thought to improve nerve conduction and to assist in lessening the movement disorders in Parkinson disease.
Dopa-responsive dystonia (DRD)
A condition that typically begins in childhood or adolescence with progressive difficulty in walking and, in some cases, spasticity and can be successfully treated with drugs. Segawa dystonia is an important variant of DRD. In Segawa dystonia, the symptoms fluctuate during the day from relative mobility in the morning to increasing disability in the afternoon and evening and after exercise. DRD may not only be rare but also rarely diagnosed since it mimics some forms of cerebral palsy.
Dorian Gray effect
Sudden aging, an abrupt change from seeming youthfulness to the reality and ravages of age, as can occur naturally or when the effects of plastic surgery and Botox treatments wear off.
Dorsum
The back or posterior side of a structure. "Dorsum" is the Latin word for the back. Something pertaining to the dorsum is dorsal. The dorsal surface of the hand is the back of the hand, the side opposite the palm. The dorsal surface of the foot is the back of the foot, the side opposite the sole. The dorsal vertebrae are the thoracic vertebrae; they form part of the back. The dorsal roots of the spinal nerves are the back roots, the posterior roots.
We thank you for using the Medical Glossary to search for Donor lymphocyte infusion. If you have a better definition for Donor lymphocyte infusion than the one presented here, please let us know by making use of the suggest a term option. This definition of Donor lymphocyte infusion may be disputed by other professionals. Our attempt is to provide easy definitions on Donor lymphocyte infusion and any other medical topic for the public at large.
This dictionary contains 19186 terms.
|
|