Medical Glossary

This glossary contains:
19186
medical terms

Dominant Progressive Foveal Dystrophy




Dominant Progressive Foveal Dystrophy

Dominant Stargardt’s disease. A degeneration of the RPE and photoreceptors of the eye. Slowly progressive, leading to legal blindness later in life. Usually starts in the 20s to 40s. Results in decreased visual acuity, central scotoma and defective color vision. There is no treatment.

RELATED TERMS
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Dominant
A genetic trait is considered dominant if it is expressed in a person who has only one copy of that gene. (In genetic terms, a dominant trait is one that is phenotypically expressed in heterozygotes). A dominant trait is opposed to a recessive trait which is expressed only when two copies of the gene are present. (In genetic terms, a recessive trait is one that is phenotypically expressed only in homozygotes).

Disease
Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

Eye
The organ of sight. The eye has a number of components. These components include but are not limited to the cornea, iris, pupil, lens, retina, macula, optic nerve, choroid and vitreous.

Blindness
Legal blindness is defined as: 1) visual acuity of 20/200 (only being able to see the big E on the eye chart) or less in the best eye even with the eyes corrected by glasses or contact lenses; or, 2) The peripheral visual field is reduced to 20 degrees of visual angle or less. Twenty degrees of visual angle is about the size of a one foot ruler held at arms length.

Acuity
The highest spatial frequency rsolvable with a grating of unity contrast (i.e. the maximum possibly contrast).

Central
In anatomy and medicine (as elsewhere), central is the opposite of "peripheral" which means away from the center.

Scotoma
An absence of vision in part of the visual field. It is present in such conditions as glaucoma, or in more serious diseases within the brain. Often detected by a visual field test.

Vision
The sense of sight.



SIMILAR TERMS
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Dominant
A genetic trait is considered dominant if it is expressed in a person who has only one copy of that gene. (In genetic terms, a dominant trait is one that is phenotypically expressed in heterozygotes). A dominant trait is opposed to a recessive trait which is expressed only when two copies of the gene are present. (In genetic terms, a recessive trait is one that is phenotypically expressed only in homozygotes).

Dominant gene
A gene which, when present on a chromosome, passes on a certain physical characteristic, even when the gene is present in only one copy. A dominant disorder can be inherited from only one parent.

Dominatrix
A female in the sadomasochistic role of total domination and discipline.



PREVIOUS AND NEXT TERMS
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Degenerative Myopia
Pathologic progressive myopia. Causes RPE and choriocapillaris atrophy and photoreceptor degeneration. Leads to reduced visual acuity, night blindness and retinal detachment, the latter requires retinal surgery.

Dermoid cyst
A congenital (born with) tumor present in infancy as a yellowish swelling on the surface of the eye. It may enlarge during puberty. The dermoid cyst can be surgically removed by an ophthalmologist.

Detached retina
A condition in which the retina separates from another layer of cells in the back of the eye, resulting in a decrease in nutrition and visual function. It may be due to a hemorrhage, trauma, tumor, vascular malformation or from traction of the vitreous to which it is attached. Sometimes, people with high myopia will develop a retinal detachment, which requires emergency surgery.

DTIC-Dome
DTIC-Dome(dacarbazine) is a Bayer medication for the treatment of metastatic malignant melanoma.

Diopter
The unit used to measure the amount of refractive or focusing power of the eye. It also refers to the strength of lens required to provide clear vision. In general, the higher the refractive error, as measured in diopters, the worse the eye.

Dominant Progressive Foveal Dystrophy

Drusen
Amorphous, sub RPE material; probably the remains of the RPE as a result of atrophy. Associated, sometimes with aging and with ARMD. There may be no symptoms present in the early stages and may lead to a reduction in visual acuity later in life.

Diagnostic
Pertaining to a diagnosis; usually refers to a characteristic or criteria which is critical for a specific diagnosis.

Diagnosis
The determination of the presence of a specific disease or infection, usually accomplished by evaluating clinical symptoms and laboratory tests.

Diazepam
A tranquilizer.

Dental clinic
A clinic specialized in dental treatment.

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This dictionary contains 19186 terms.







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