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Cutis laxa
Cutis laxaA dermatologic condition characterized by unusually loose skin which may hang in pendulous folds. Cutis laxa is usually a genetic disorder. A mild autosomal dominant form can be caused by mutation in the elastin gene (the ELN gene). Mutations in the gene encoding fibulin-5 (FBLN5) can cause either autosomal dominant or a more severe autosomal recessive form of cutis laxa. There is also an X-linked type of cutis laxa. RELATED TERMS-------------------------------------- Dermatologic Having to do with the skin. Condition The term "condition" has a number of biomedical meanings including the following: 1.An unhealthy state, such as in "this is a progressive condition." 2.A state of fitness, such as "getting into condition." 3.Something that is essential to the occurrence of something else; essentially a "precondition." 4.As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning. Skin Skin is an organ of the integumentary system; which is composed of a layer of tissues that protect underlying muscles and organs. Skin is used for insulation, vitamin D production, sensation, and excretion (through sweat). Cutis The skin. Cutis marmorata is marble skin, a normal response to cold. Genetic Hereditary. Having to do with the genes. Autosomal "Pertaining to a chromosome that is not a sex chromosome; relating to any one of the chromosomes save the sex chromosomes. People normally have 22 pairs of autosomes (44 autosomes) in each cell together with two sex chromosomes (X and Y in the male and XX in the female). " Dominant A genetic trait is considered dominant if it is expressed in a person who has only one copy of that gene. (In genetic terms, a dominant trait is one that is phenotypically expressed in heterozygotes). A dominant trait is opposed to a recessive trait which is expressed only when two copies of the gene are present. (In genetic terms, a recessive trait is one that is phenotypically expressed only in homozygotes). Mutation A change in DNA that alters a gene and thus the gene's product, leading in some cases to deformity or disease. Mutations can occur spontaneously during cell division or can be triggered by environmental stresses, such as sunlight, radiation, and chemicals. Elastin A protein that coil and recoils like a spring within the elastic fibers of connective tissue and accounts for the elasticity of structures such the skin, blood vessels, heart, lungs, intestines, tendons, and ligaments. Elastin functions in connective tissue together with collagen. Whereas elastin provides elasticity, collagen provides rigidity to connective tissue. Elastin is normally no longer made after puberty and aging begins. Also called elasticin. Gene 1. A unit of DNA that carries information for the biosynthesis of a specific product in the cell. 2. Ultimate unit by which inheritable characteristics are transmitted to succeeding generations in all living organisms. Genes are contained by, and arranged along the length of, the chromosome. The gene is composed of deoxyribonucleic acid (DNA). Each chromosome of each species has a definite number and arrangement of genes, which govern both the structure and metabolic functions of the cells and thus of the entire organism. SIMILAR TERMS-------------------------------------- Cutis The skin. Cutis marmorata is marble skin, a normal response to cold. Cutis anserina Better known as goose bumps, a temporary local change in the skin when it becomes rougher due to erection of little muscles, as from cold, fear, or excitement. Cutivate Cutivate is a prescription or over-the-counter drug which is (or once was) approved in the United States and possibly in other countries. Active ingredient(s): fluticasone propionate. PREVIOUS AND NEXT TERMS-------------------------------------- Cutaneous allodynia Pain resulting from an innocuous stimulus to normal skin or scalp. The stumulus that triggers allodynia is not normally painful. The pain can be provoked by combing or brushing the hair, shaving, showering, wearing glasses or earrings. The pressure of a single strand of hair reportedly can feel like a jab with a white-hot knife. Cutaneous allodynia is believed due to a transient increase in the responsiveness of central pain neurons that process information arising from the skin. It is commonly associated with migraine. Cutaneous papilloma A small tag of skin that may have a stalk (a peduncle). Cutaneous papillomas may appear on the skin almost anywhere although the favorite locales are the eyelids, neck, armpits (axillae), upper chest, and groin. Cutaneous syndactyly A condition in which fingers or toes are joined together, and the joining involves only the skin, not the bones. Cutaneous syndactyly is the opposite of bony syndactyly, in which the bones are of the digits are joined. Cutis The skin. Cutis marmorata is marble skin, a normal response to cold. Cutis anserina Better known as goose bumps, a temporary local change in the skin when it becomes rougher due to erection of little muscles, as from cold, fear, or excitement. Cutis laxa Cuts Severed skin. Washing a cut or scrape with soap and water and keeping it clean and dry is all that is required to care for most wounds. Putting alcohol hydrogen peroxide, and iodine into a wound can delay healing and should be avoided. Seek medical care early if you think that you might need stitches. Any delay can increase the rate of wound infection. Any puncture wound through tennis shoes has a high risk of infection and should be seen by your healthcare professional. Any redness, swelling, increased pain, or pus draining from the wound may indicate an infection that requires professional care. Cutting for the stone The removal of kidney or bladder stones by surgery. The procedure is today called lithotomy. CVA Cerebrovascular accident. CVC Commonly used abbreviation for a Central Venous Catheter, a catheter (tube) that is passed through a vein to end up in the thoracic (chest) portion of the vena cava (the large vein returning blood to the heart) or in the right atrium of the heart. CVS 1. Chorionic villus sampling, a procedure for first-trimester prenatal diagnosis. 2. Cyclic vomiting syndrome, also known as abdominal migraine. We thank you for using the Medical Glossary to search for Cutis laxa. If you have a better definition for Cutis laxa than the one presented here, please let us know by making use of the suggest a term option. This definition of Cutis laxa may be disputed by other professionals. Our attempt is to provide easy definitions on Cutis laxa and any other medical topic for the public at large.
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