Medical Glossary

This glossary contains:
19186
medical terms

Crossover study




Crossover study

A type of clinical trial in which the study subjects receive each treatment in a random order. With this type of study, every patient serves as his or her own control.

RELATED TERMS
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Clinical
That which can be observed in patients. Research that uses patients to test new treatments, as opposed to laboratory testing or research in animals.



SIMILAR TERMS
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Cross bite
Reverse biting relationship of upper and lower teeth; aka "under bite," as in Class III malocclusuion (prognathic jaw).

Cross training
Doing two or more aerobic activities such as jogging, bicycling, and swimming on a regular basis.

Cross-reactivity
The ability of an antibody, specific for one antigen, to react with a second antigen; a measure of relatedness between two different antigenic substances.

Cross-section
In anatomy, a cross-section is a transverse cut through a structure or tissue. The opposite of a cross-section is a longitudinal section. By analogy, a study may be cross-sectional or longitudinal.

Cross-sectional study
A study done at one time, not over the course of time. A cross-sectional study might be of a disease such as AIDS at one point in time to learn its prevalence and distribution within the population. Also known as a synchronic study.

Crossed embolism
Passage of a clot (thrombus) from a vein to an artery. When clots in veins break off (embolize) , they travel first to the right side of the heart and, normally, then to the lungs where they lodge. The lungs act as a filter to prevent the clots from entering the arterial circulation. However, when there is a hole in the wall between the two upper chambers of the heart (an atrial septal defect), a clot can crossparadoxically from the right to the left side of the heart, then pass into the arteries. Once in the arterial circulation, a clot can travel to the brain, block a vessel there, and cause a stroke (cerebrovascular accident). Because of the risk of stroke from crossed embolism, it is usually recommended that even small atrial septal defects be closed (repaired).

Crossing over
The exchange of genetic material between two paired chromosomes. Crossing over is a way to recombine the genetic material so that each person (except for identical twins) is genetically unique.

Crossover trial
In crossover trials, each subject receives both treatments being compared (often the test drug for one period and the placebo for another period). Such trials are used for patients who have a stable, usually chronic, condition during both treatment period.

Crossroads Regional Medical Center
The Crossroads Regional Medical Center is a hospital in Wentzville, Missouri, United States.



PREVIOUS AND NEXT TERMS
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Cross training
Doing two or more aerobic activities such as jogging, bicycling, and swimming on a regular basis.

Cross-section
In anatomy, a cross-section is a transverse cut through a structure or tissue. The opposite of a cross-section is a longitudinal section. By analogy, a study may be cross-sectional or longitudinal.

Cross-sectional study
A study done at one time, not over the course of time. A cross-sectional study might be of a disease such as AIDS at one point in time to learn its prevalence and distribution within the population. Also known as a synchronic study.

Crossed embolism
Passage of a clot (thrombus) from a vein to an artery. When clots in veins break off (embolize) , they travel first to the right side of the heart and, normally, then to the lungs where they lodge. The lungs act as a filter to prevent the clots from entering the arterial circulation. However, when there is a hole in the wall between the two upper chambers of the heart (an atrial septal defect), a clot can crossparadoxically from the right to the left side of the heart, then pass into the arteries. Once in the arterial circulation, a clot can travel to the brain, block a vessel there, and cause a stroke (cerebrovascular accident). Because of the risk of stroke from crossed embolism, it is usually recommended that even small atrial septal defects be closed (repaired).

Crossing over
The exchange of genetic material between two paired chromosomes. Crossing over is a way to recombine the genetic material so that each person (except for identical twins) is genetically unique.

Crossover study

Crotch
A nonmedical term in common usage for the region where the legs come together, the place where the lower limbs divide.

CRP
C-reactive protein.

Cruciate
Cross-shaped. The cruciate ligaments are so-named because they cross each other. For example, there are cruciate ligaments that cross within the knee joint. These ligaments help provide stability and strength to the knee joint.

Cruciate ligament, anterior
The knee joint is surrounded by a joint capsule with ligaments strapping the inside and outside of the joint (collateral ligaments) as well as crossing within the joint (cruciate ligaments). These ligaments provide stability and strength to the knee joint. The anterior cruciate ligament (cruciate means shaped like a cross) is in the front.

Cruciate ligament, posterior
The knee joint is surrounded by a joint capsule with ligaments strapping the inside and outside of the joint (collateral ligaments) as well as crossing within the joint (cruciate ligaments). These ligaments provide stability and strength to the knee joint. The posterior cruciate ligament (cruciate means shaped like a cross) crosses behind the anterior cruciate ligament within the joint.

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This dictionary contains 19186 terms.







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