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Cross-reactivity
Cross-reactivity The ability of an antibody, specific for one antigen, to react with a second antigen; a measure of relatedness between two different antigenic substances.
RELATED TERMS-------------------------------------- Antibody An infection-fighting protein molecule in blood or secretory fluids that tags, neutralizes, and helps destroy pathogenic microorganisms (eg, bacteria, viruses) or toxins. Antibodies, known generally as immunoglobulins, are made and secreted by B-lymphocytes in response to stimulation by antigens. Each specific antibody binds only to the specific antigen that stimulated its production. Antigen A substance which, when present in animal tissue, stimulates the production of antibodies SIMILAR TERMS-------------------------------------- Cross bite Reverse biting relationship of upper and lower teeth; aka "under bite," as in Class III malocclusuion (prognathic jaw). Cross training Doing two or more aerobic activities such as jogging, bicycling, and swimming on a regular basis. Cross-section In anatomy, a cross-section is a transverse cut through a structure or tissue. The opposite of a cross-section is a longitudinal section. By analogy, a study may be cross-sectional or longitudinal. Cross-sectional study A study done at one time, not over the course of time. A cross-sectional study might be of a disease such as AIDS at one point in time to learn its prevalence and distribution within the population. Also known as a synchronic study. Crossed embolism Passage of a clot (thrombus) from a vein to an artery. When clots in veins break off (embolize) , they travel first to the right side of the heart and, normally, then to the lungs where they lodge. The lungs act as a filter to prevent the clots from entering the arterial circulation. However, when there is a hole in the wall between the two upper chambers of the heart (an atrial septal defect), a clot can crossparadoxically from the right to the left side of the heart, then pass into the arteries. Once in the arterial circulation, a clot can travel to the brain, block a vessel there, and cause a stroke (cerebrovascular accident). Because of the risk of stroke from crossed embolism, it is usually recommended that even small atrial septal defects be closed (repaired). Crossing over The exchange of genetic material between two paired chromosomes. Crossing over is a way to recombine the genetic material so that each person (except for identical twins) is genetically unique. Crossover study A type of clinical trial in which the study subjects receive each treatment in a random order. With this type of study, every patient serves as his or her own control. Crossover trial In crossover trials, each subject receives both treatments being compared (often the test drug for one period and the placebo for another period). Such trials are used for patients who have a stable, usually chronic, condition during both treatment period. Crossroads Regional Medical Center The Crossroads Regional Medical Center is a hospital in Wentzville, Missouri, United States. PREVIOUS AND NEXT TERMS-------------------------------------- Complement components An enzymatic system of serum proteins triggered by the classical and alternative pathways, and resulting in target cell lysis, phagocytosis, opsonization and chemotaxis. Complement receptor A structure found on erythrocytes, lymphocytes, neutrophils, monocytes and macrophages that binds C3 fragments. Constant region The invariant carboxyl-terminal portion of an antibody molecule, as distinct from the variable region which is at the amino-terminal of the chain. C region The invariant carboxyl-terminal portion of an antibody molecule, as distinct from the variable region which is at the amino-terminal of the chain. Coomb's test A test named for its originator, R.R.A. Coombs, used to detect non-agglutinating antibodies on red blood cells by addition of an anti-immunoglobulin antibody. Cross-reactivity Cytotoxic T cell Cell that kills target cells bearing appropriate antigen within the groove of an MHC class I molecule that is identical to that of the T cell. Cytolytic T cell Cell that kills target cells bearing appropriate antigen within the groove of an MHC class I molecule that is identical to that of the T cell. Cabbage soup diet A specific kind of diet based on cabbeg soup. Calcium channel blocker Or calcium blocker. A medication that lowers blood pressure. Calculi Stones or solid lumps such as gallstones. We thank you for using the Medical Glossary to search for Cross-reactivity. If you have a better definition for Cross-reactivity than the one presented here, please let us know by making use of the suggest a term option. This definition of Cross-reactivity may be disputed by other professionals. Our attempt is to provide easy definitions on Cross-reactivity and any other medical topic for the public at large.
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