Medical Glossary

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19186
medical terms

Colchicine




Colchicine

A substance found in a plant that is used in clinical medicine for the treatment of gouty arthritis and in the laboratory to arrest cells during cell division (by disrupting the spindle) so their chromosomes can be visualized. The name colchicine is from the Greek kolchikon meaning autumn crocus or meadow saffron, the plant from which colchicine was originally isolated.

RELATED TERMS
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Clinical
That which can be observed in patients. Research that uses patients to test new treatments, as opposed to laboratory testing or research in animals.

Arthritis
Inflammation of a joint, usually accompanied by pain, swelling, and stiffness, and resulting from infection, trauma, degenerative changes, metabolic disturbances, or other causes. Arthritis occurs in various forms, such as the arthritis associated with infections, osteoarthritis, or rheumatoid arthritis. Many forms of vasculitis can also be associated with arthritis.

Cell
Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid.

Chromosomes
Filaments of genetic material in every cell nucleus that are made up of genes and that transmit genetic information from one generation of cells to the next.

Colchicine
A substance found in a plant that is used in clinical medicine for the treatment of gouty arthritis and in the laboratory to arrest cells during cell division (by disrupting the spindle) so their chromosomes can be visualized. The name colchicine is from the Greek kolchikon meaning autumn crocus or meadow saffron, the plant from which colchicine was originally isolated.



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Coitophobia
An abnormal and persistent fear of male-female sexual intercourse. Sufferers from coitophobia experience undue anxiety because they are preoccupied with failing in some way while having heterosexual intercourse. Among the symptoms of coitophobia are failure to achieve an erection (erectile dysfunction) and failure to achieve orgasm (anorgasmy).

Coitus interruptus
A method of contraception, also called withdrawal, in which the man withdraws his penis from the vagina before ejaculation. Fertilization is prevented because the sperm do not enter the vagina.

Coke
Street name for cocaine, the most potent stimulant of natural origin, a bitter addictive anesthetic (pain blocker) which is extracted from the leaves of the coca scrub (Erythroxylon coca) indigenous to the Andean highlands of South America.

COL2A1
The gene responsible for the production of the alpha1(II) chain of type II collagen. Mutations in the COL2A1 gene lead to a number of different heritable skeletal disorders, including achondrogenesis type II, hypochondrogenesis, Kniest dysplasia, spondyloepimetaphyseal dysplasia of the Strudwick type, spondyloepiphyseal dysplasia congenita, and Stickler syndrome.

COL4A5
The gene for basement membrane type IV collagen alpha-5 chain. COL4A5 is on the X chromosome in band Xq22.3. Mutations in COL4A5 are responsible for the X-linked form of Alport syndrome, a type of hereditary kidney disease. Also known as Collagen IV alpha 5; Collagen, type IV, alpha 5.

Colchicine

COLD (chronic obstructive lung disease)
Any disorder that persistently obstructs bronchial airflow. COLD mainly involves two related diseases -- chronic bronchitis and emphysema.

Cold injury
Cold injuries include chilblains, "trench foot," and frostbite.

Condition
The term "condition" has a number of biomedical meanings including the following: 1.An unhealthy state, such as in "this is a progressive condition." 2.A state of fitness, such as "getting into condition." 3.Something that is essential to the occurrence of something else; essentially a "precondition." 4.As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

Cold, common
A viral upper respiratory tract infection. This contagious illness can be caused by many different types of viruses, and the body can never build up resistance to all of them. For this reason, colds are a frequent and recurring problem. In fact kindergarten children average 12 colds per year, while adolescents and adults have around seven colds per year.

Cold, June
"A popular term for hay fever. Although the symptoms of a ""June cold"" may be quite similar to those of a real cold, the term ""June cold"" is a misnomer. Unlike a real cold, it is not caused by a virus, but by allergy. It is therefore also known as allergic rhinitis, a runny nose due to an allergy."

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This dictionary contains 19186 terms.







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