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Co-stimulation
Co-stimulationAn event in the immune system involving the delivery of a second signal by an antigen-presenting cell. The second signal rescues the activated T cell from anergy (which is a state of immune unresponsiveness), allowing the T cell to produce the lymphokines necessary for the growth of additional T cells. RELATED TERMS-------------------------------------- Event A set of outcomes. Cardiovascular events might include a heart attack and gastrointestinal events a GI bleed. The use of the term "event" in medicine comes from probability theory. Immune Resistant to a particular disease. Delivery See drug delivery. Cell Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid. Lymphokines Soluble substances secreted by lymphocytes, which have a variety of effects on lymphocytes and other cell types. SIMILAR TERMS-------------------------------------- PREVIOUS AND NEXT TERMS-------------------------------------- CNR2 Cannabinoid receptor 2. CNS (central nervous system) That part of the nervous system that consists of the brain and spinal cord. CNS prophylaxis Chemotherapy or radiation therapy to the central nervous system (CNS). This is preventative treatment. It is given to kill cancer cells that may be in the brain and spinal cord, even though no cancer has been detected there. Co-morbid Pertaining to two or more disorders simultaneously. Co-payment A payment made by an individual who has health insurance, usually at the time a service is received, to offset some of the cost of care. Co-payments are a common feature of HMO (Health Maintenance Organization) and PPO (Preferred Provider Organization) health plans in the US. Co-payment size may vary depending on the service, generally with low copayments required for visits to a regular medical provider and higher payments for services received in the emergency room, the latter intended to discourage insured persons from using the emergency room unless it is absolutely necessary. Also called co-insurance. Co-stimulation Coagulation In medicine, the clotting of blood. The process by which the blood clots to form solid masses, or clots. Coagulation, laser The coagulation (clotting) of tissue using a laser. A coagulation laser produces light in the visible green wavelength that is selectively absorbed by hemoglobin, the pigment in red blood cells, in order to seal off bleeding blood vessels. Coarctation A narrowing, a stricture, a constriction. Although the best known coarctation is of the aorta, any artery can have a coarctation. The word "coarctation" comes from the Latin "coartare" meaning :to press together." The sides of the vessel at the point of a coarctation appear pressed together. Coarctation of the aorta A congenital constriction of the aorta, impeding the flow of blood below the level of the constriction and increasing blood pressure above the constriction. Symptoms may not be evident at birth but may develop as soon as the first week after birth with congestive heart failure or high blood pressure that call for early surgery. The surgery otherwise can be delayed. The outlook after surgery is favorable. Some cases have been treated by balloon angioplasty. Coated stent Also known as a medicated stent. A tiny cage coated with a drug to prop open an artery and prevent it from closing again. We thank you for using the Medical Glossary to search for Co-stimulation. If you have a better definition for Co-stimulation than the one presented here, please let us know by making use of the suggest a term option. This definition of Co-stimulation may be disputed by other professionals. Our attempt is to provide easy definitions on Co-stimulation and any other medical topic for the public at large.
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