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C region
C region The invariant carboxyl-terminal portion of an antibody molecule, as distinct from the variable region which is at the amino-terminal of the chain.
RELATED TERMS-------------------------------------- Antibody An infection-fighting protein molecule in blood or secretory fluids that tags, neutralizes, and helps destroy pathogenic microorganisms (eg, bacteria, viruses) or toxins. Antibodies, known generally as immunoglobulins, are made and secreted by B-lymphocytes in response to stimulation by antigens. Each specific antibody binds only to the specific antigen that stimulated its production. SIMILAR TERMS-------------------------------------- PREVIOUS AND NEXT TERMS-------------------------------------- Combinatorial joining The joining of segments of DNA to generate essentially new genetic information, as occurs with Ig genes during the development of B cells. Combinatorial joining allows multiple opportunities for 2 sets of genes to combine in different ways. Complement A series of serum proteins involved in the mediation of immune reactions. The complement cascade is triggered classically by the interaction of antibody with specific antigen. Complement components An enzymatic system of serum proteins triggered by the classical and alternative pathways, and resulting in target cell lysis, phagocytosis, opsonization and chemotaxis. Complement receptor A structure found on erythrocytes, lymphocytes, neutrophils, monocytes and macrophages that binds C3 fragments. Constant region The invariant carboxyl-terminal portion of an antibody molecule, as distinct from the variable region which is at the amino-terminal of the chain. C region Coomb's test A test named for its originator, R.R.A. Coombs, used to detect non-agglutinating antibodies on red blood cells by addition of an anti-immunoglobulin antibody. Cross-reactivity The ability of an antibody, specific for one antigen, to react with a second antigen; a measure of relatedness between two different antigenic substances. Cytotoxic T cell Cell that kills target cells bearing appropriate antigen within the groove of an MHC class I molecule that is identical to that of the T cell. Cytolytic T cell Cell that kills target cells bearing appropriate antigen within the groove of an MHC class I molecule that is identical to that of the T cell. Cabbage soup diet A specific kind of diet based on cabbeg soup. We thank you for using the Medical Glossary to search for C region. If you have a better definition for C region than the one presented here, please let us know by making use of the suggest a term option. This definition of C region may be disputed by other professionals. Our attempt is to provide easy definitions on C region and any other medical topic for the public at large.
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