Medical Glossary

This glossary contains:
19186
medical terms

CDNA




CDNA

Complementary DNA. cDNA is single-stranded DNA made in the laboratory from a messenger RNA template under the aegis of the enzyme reverse transcriptase. This form of DNA is often used as a probe in the physical mapping of a chromosome.

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DNA
Deoxyribo-Nucleic acid. DNA molecules carry the genetic information necessary for the organization and functioning of most living cells and control the inheritance of characteristics.

CDNA
Complementary DNA. cDNA is single-stranded DNA made in the laboratory from a messenger RNA template under the aegis of the enzyme reverse transcriptase. This form of DNA is often used as a probe in the physical mapping of a chromosome.

Enzyme
A cellular protein whose shape allows it to hold together several other molecules in close proximity to each other. In this way, enzymes are able to induce chemical reactions in other substances with little expenditure of energy and without being changed themselves. Basically, an enzyme acts as a catalyst.

Chromosome
A structural unit within a eukaryotic nucleus that carries genes. A chromosome consists of a long, continuous strand of DNA and associated proteins.



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CCHF
Crimean-Congo hemorrhagic fever.

CCR5
A chemokine receptor found on monocytes and lymphocytes that serves as the coreceptor for HIV. HIV strains that use this coreceptor are referred to as R5 viruses. Polymorphisms in the coding and non-coding regions of the CCR5 gene influence the natural history of HIV infection. CCR5 (or CCCR5) stands for the CC chemokine receptor 5.

CD10
A cell surface enzyme with neutral metalloendopeptidase activity. CD10 is also known as CALLA (common acute lymphocytic leukemia antigen). It serves as a marker for the common form of ALL (acute lymphocytic leukemia) as well as for Burkitt lymphoma and follicular germinal center lymphoma. CD10/CALLA is normally present on the surface of early lymphoid cells as well as on a number of other types of normal cells, such as especially cells in the kidney.

CD4
A large glycoprotein molecule found on the surface of T lymphocytes that serves as the receptor for HIV.

CD40
A receptor molecule on the cell surface of all mature B cells (B lymphocytes), most B-cell malignancies, and monocytes, dendritic cells (in the nervous system), endothelial cells (within blood vessels), and epithelial cells. CD40 is a member of the tumor necrosis factor superfamily. Together with CD40 ligand, the molecule that binds to it, CD40 is an important contributor to the inflammatory processes that lead to atherosclerosis and thrombosis (clotting). The gene encoding CD40 is on chromosome 20.

CDNA

CEA assay
Carcinoembryonic antigen (CEA) is a protein found in many types of cells but associated with tumors and the developing fetus.

Cecal
Pertaining to the cecum (also spelled caecum), the first portion of the large bowel, situated in the lower right quadrant of the abdomen.

Celiac disease
A disorder resulting from an immune reaction to gluten, a protein found in wheat and related grains, and present in many foods. Celiac disease causes impaired absorption and digestion of nutrients through the small intestine. Symptoms include frequent diarrhea and weight loss. A skin condition dermatitis herpetiformis can be associated with celiac disease. The most accurate test for celiac disease is a biopsy of the involved small bowel. Treatment is to avoid gluten in the diet. Medications are used for refractory (stubborn) celiac disease.

Cell cloning
The process of producing a group of cells (clones), all genetically identical, from a single ancestral cell.

Cell fusion
The melding of two or more cells into one cell called a heterokaryon. A heterokaryon may reproduce itself for at least several generations. Cell fusion provides a method for assigning specific genes to specific chromosomes.

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This dictionary contains 19186 terms.







dna / cna / cda / cdn / ccdna / cddna / cdnna / cdnaa / xdna / sdna / ddna / fdna / vdna / dna / cena / crna / cfna / cvna / ccna / cxna / csna / cwna / cdba / cdha / cdja / cdma / cd a / cdnq / cdnw / cdns / cdnx / cdnz /