![]() |
||||||||||||||||
|
||||||||||||||||
|
CD10
CD10A cell surface enzyme with neutral metalloendopeptidase activity. CD10 is also known as CALLA (common acute lymphocytic leukemia antigen). It serves as a marker for the common form of ALL (acute lymphocytic leukemia) as well as for Burkitt lymphoma and follicular germinal center lymphoma. CD10/CALLA is normally present on the surface of early lymphoid cells as well as on a number of other types of normal cells, such as especially cells in the kidney. RELATED TERMS-------------------------------------- Cell Fundamental structural unit of all life. The cell consists primarily of an outer plasma membrane, which separates it from the environment; the genetic material (DNA), which encodes heritable information for the maintainance of life; and the cytoplasm, a heterogeneous assemblage of ions, molecules, and fluid. Enzyme A cellular protein whose shape allows it to hold together several other molecules in close proximity to each other. In this way, enzymes are able to induce chemical reactions in other substances with little expenditure of energy and without being changed themselves. Basically, an enzyme acts as a catalyst. CD10 A cell surface enzyme with neutral metalloendopeptidase activity. CD10 is also known as CALLA (common acute lymphocytic leukemia antigen). It serves as a marker for the common form of ALL (acute lymphocytic leukemia) as well as for Burkitt lymphoma and follicular germinal center lymphoma. CD10/CALLA is normally present on the surface of early lymphoid cells as well as on a number of other types of normal cells, such as especially cells in the kidney. CALLA Common acute lymphocytic leukemia antigen. Acute 1. Of short course. 2. Severe, but of a short duration. Not chronic. Leukemia Cancer of white blood cells. Acute leukemias are characterized by the presence of "blasts," which are immature white blood cells. Large quantities of blasts generally overgrow the bone marrow, leaving very little space for normal bone marrow cells. This type generally requires immediate treatment. Chronic leukemias are those characterized by a large and uncontrolled growth of more mature white blood cells. These types of leukemias tend not to progress as rapidly, and treatment is often milder than that of acute leukemias. Lymphoma Cancer of the lymphoid tissues. Lymphomas are often described as being large cell or small cell types, cleaved or non-cleaved, or diffuse or nodular. The different types often have different prognoses. Lymphomas can also be referred to by the organs where they are active, such as CNS lymphomas, which are in the central nervous system, and GI lymphomas, which are in the gastrointestinal tract. The types of lymphomas most commonly associated with HIV infection are called non-Hodgkin's lymphomas or B cell lymphomas. In these types of cancers, certain cells of the lymphatic. Kidney One of the paired organs that excrete urine. The kidneys are bean-shaped organs (about 11 cm long, 5 cm wide, and 3 cm thick) lying on either side of the vertebral column, posterior to the peritoneum, about opposite the twelfth thoracic and first three lumbar vertebrae. SIMILAR TERMS-------------------------------------- PREVIOUS AND NEXT TERMS-------------------------------------- Cavities Holes in the two outer layers of a tooth called the enamel and the dentin. The enamel is the outermost white hard surface and the dentin is the yellow layer just beneath enamel. Both layers serve to protect the inner living tooth tissue called the pulp, where blood vessels and nerves reside. Small cavities may not cause pain, and may be unnoticed by the patient. Larger cavities can collect food, and the inner pulp of the affected tooth can become irritated by bacterial toxins, foods that are cold, hot, sour, or sweet - causing toothache. Also referred to as caries. Cavity, abdominal The cavity within the abdomen, the space between the abdominal wall and the spine. CBT Cognitive behavior therapy. CCHF Crimean-Congo hemorrhagic fever. CCR5 A chemokine receptor found on monocytes and lymphocytes that serves as the coreceptor for HIV. HIV strains that use this coreceptor are referred to as R5 viruses. Polymorphisms in the coding and non-coding regions of the CCR5 gene influence the natural history of HIV infection. CCR5 (or CCCR5) stands for the CC chemokine receptor 5. CD10 CD4 A large glycoprotein molecule found on the surface of T lymphocytes that serves as the receptor for HIV. CD40 A receptor molecule on the cell surface of all mature B cells (B lymphocytes), most B-cell malignancies, and monocytes, dendritic cells (in the nervous system), endothelial cells (within blood vessels), and epithelial cells. CD40 is a member of the tumor necrosis factor superfamily. Together with CD40 ligand, the molecule that binds to it, CD40 is an important contributor to the inflammatory processes that lead to atherosclerosis and thrombosis (clotting). The gene encoding CD40 is on chromosome 20. CDNA Complementary DNA. cDNA is single-stranded DNA made in the laboratory from a messenger RNA template under the aegis of the enzyme reverse transcriptase. This form of DNA is often used as a probe in the physical mapping of a chromosome. CEA assay Carcinoembryonic antigen (CEA) is a protein found in many types of cells but associated with tumors and the developing fetus. Cecal Pertaining to the cecum (also spelled caecum), the first portion of the large bowel, situated in the lower right quadrant of the abdomen. We thank you for using the Medical Glossary to search for CD10. If you have a better definition for CD10 than the one presented here, please let us know by making use of the suggest a term option. This definition of CD10 may be disputed by other professionals. Our attempt is to provide easy definitions on CD10 and any other medical topic for the public at large.
|
|||||||||||||||
| © Medical Glossary 2005. All rights reserved. | ||||||||||||||||
| d10 / c10 / cd0 / cd1 / ccd10 / cdd10 / cd110 / cd100 / xd10 / sd10 / dd10 / fd10 / vd10 / d10 / ce10 / cr10 / cf10 / cv10 / cc10 / cx10 / cs10 / cw10 / cd20 / cdw0 / cdq0 / cd`0 / cd1- / cd1[ / cd1p / cd1o / cd19 / | ||||||||||||||||