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BP1
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BP1Beta protein 1, a member of the homeobox gene family important to early development of the fetus. (Specifically, BP1 belongs to the DLX homeobox family and is an isoform of the DLX4 gene.) BP1 acts as a transcription factor that turns other genes on and off. It regulates the beta globin gene, from whence comes its name. BP1 is overexpressed in a large proportion of cases of acute myeloid leukemia (AML) and breast cancer.
RELATED TERMS--------------------------------------
Protein
Any of a group of complex organic compounds which contain carbon, hydrogen, oxygen, nitrogen, and usually sulfur, the characteristic element being nitrogen. Proteins, the principal constituents of the protoplasm of all cells, are of high molecular weight and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and each protein has a unique genetically defined amino acid sequence which determines its specific shape and function. Their roles include enzymatic catalysis, transport and storage, coordinated motion, nerve impulse generation and many others.
Gene
1. A unit of DNA that carries information for the biosynthesis of a specific product in the cell. 2. Ultimate unit by which inheritable characteristics are transmitted to succeeding generations in all living organisms. Genes are contained by, and arranged along the length of, the chromosome. The gene is composed of deoxyribonucleic acid (DNA). Each chromosome of each species has a definite number and arrangement of genes, which govern both the structure and metabolic functions of the cells and thus of the entire organism.
Family
1. A group of individuals related by blood or marriage or by a feeling of closeness. 2. A biological classification of related plants or animals that is a division below the order and above the genus. 3. A group of genes related in structure and in function that descended from an ancestral gene. 4. A group of gene products similarly related in structure and function and of shared genetic descent. 5. Parents and their children. The most fundamental social group in humans.
Development
The process of growth and differentiation.
Fetus
The stage of human development from 10 weeks' gestation until birth.
Transcription
Making an RNA copy from a gene or other DNA sequence. Transcription is the first step in gene expression.
Genes
Basic, functional units of heredity, each occupying a specific place on a chromosome.
Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.
Leukemia
Cancer of white blood cells. Acute leukemias are characterized by the presence of "blasts," which are immature white blood cells. Large quantities of blasts generally overgrow the bone marrow, leaving very little space for normal bone marrow cells. This type generally requires immediate treatment. Chronic leukemias are those characterized by a large and uncontrolled growth of more mature white blood cells. These types of leukemias tend not to progress as rapidly, and treatment is often milder than that of acute leukemias.
Breast
The breast refers to the front of the chest or, more specifically, to the mammary gland. The mammary gland is a milk producing gland. It is composed largely of fat. Within the mammary gland is a complex network of branching ducts. These ducts exit from sac-like structures called lobules, which can produce milk in females. The ducts exit the breast at the nipple.
Cancer
Any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream.
SIMILAR TERMS--------------------------------------
PREVIOUS AND NEXT TERMS--------------------------------------
Bowel disorders and fiber
High fiber diets help delay the progression of diverticulosis and, at least, reduce the bouts of diverticulitis. In many cases, it helps reduce the symptoms of the Irritable Bowel Syndrome (IBS). It is generally accepted that a diet high in fiber is protective, or at least reduces the incidence, of colon polyps and colon cancer.
Bowel sounds
The gurgling, rumbling, or growling noises from the abdomen caused by the muscular contractions of peristalsis, the process that moves the contents of the stomach and intestines downward.
Bowen disease
An early stage of skin cancer.
BP (genetic)
In genetics, base pair.
BP (medical)
Commonly used abbreviation for blood pressure.
BP1
BPH
Benign prostatic hyperplasia which is also known as benign prostatic hypertrophy. Nonmalignant enlargement of the prostate gland.
BPPV (benign paroxysmal positional vertigo)
A balance disorder that results in the sudden onset of dizziness, spinning, or vertigo when moving the head.
Brace, foot-drop
See Ankle-foot orthosis.
Brace, Milwaukee
One of the two main types of braces used to treat the lateral curve of the spine in scoliosis. This brace can be worn to correct any curve in the spine.
Brachial artery
The artery that runs from the shoulder down to the elbow.
RELATED TERMS--------------------------------------
Protein
Any of a group of complex organic compounds which contain carbon, hydrogen, oxygen, nitrogen, and usually sulfur, the characteristic element being nitrogen. Proteins, the principal constituents of the protoplasm of all cells, are of high molecular weight and consist essentially of combinations of a-amino acids in peptide linkages. Twenty different amino acids are commonly found in proteins, and each protein has a unique genetically defined amino acid sequence which determines its specific shape and function. Their roles include enzymatic catalysis, transport and storage, coordinated motion, nerve impulse generation and many others.
Gene
1. A unit of DNA that carries information for the biosynthesis of a specific product in the cell. 2. Ultimate unit by which inheritable characteristics are transmitted to succeeding generations in all living organisms. Genes are contained by, and arranged along the length of, the chromosome. The gene is composed of deoxyribonucleic acid (DNA). Each chromosome of each species has a definite number and arrangement of genes, which govern both the structure and metabolic functions of the cells and thus of the entire organism.
Family
1. A group of individuals related by blood or marriage or by a feeling of closeness. 2. A biological classification of related plants or animals that is a division below the order and above the genus. 3. A group of genes related in structure and in function that descended from an ancestral gene. 4. A group of gene products similarly related in structure and function and of shared genetic descent. 5. Parents and their children. The most fundamental social group in humans.
Development
The process of growth and differentiation.
Fetus
The stage of human development from 10 weeks' gestation until birth.
Transcription
Making an RNA copy from a gene or other DNA sequence. Transcription is the first step in gene expression.
Genes
Basic, functional units of heredity, each occupying a specific place on a chromosome.
Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.
Leukemia
Cancer of white blood cells. Acute leukemias are characterized by the presence of "blasts," which are immature white blood cells. Large quantities of blasts generally overgrow the bone marrow, leaving very little space for normal bone marrow cells. This type generally requires immediate treatment. Chronic leukemias are those characterized by a large and uncontrolled growth of more mature white blood cells. These types of leukemias tend not to progress as rapidly, and treatment is often milder than that of acute leukemias.
Breast
The breast refers to the front of the chest or, more specifically, to the mammary gland. The mammary gland is a milk producing gland. It is composed largely of fat. Within the mammary gland is a complex network of branching ducts. These ducts exit from sac-like structures called lobules, which can produce milk in females. The ducts exit the breast at the nipple.
Cancer
Any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream.
SIMILAR TERMS--------------------------------------
PREVIOUS AND NEXT TERMS--------------------------------------
Bowel disorders and fiber
High fiber diets help delay the progression of diverticulosis and, at least, reduce the bouts of diverticulitis. In many cases, it helps reduce the symptoms of the Irritable Bowel Syndrome (IBS). It is generally accepted that a diet high in fiber is protective, or at least reduces the incidence, of colon polyps and colon cancer.
Bowel sounds
The gurgling, rumbling, or growling noises from the abdomen caused by the muscular contractions of peristalsis, the process that moves the contents of the stomach and intestines downward.
Bowen disease
An early stage of skin cancer.
BP (genetic)
In genetics, base pair.
BP (medical)
Commonly used abbreviation for blood pressure.
BP1
BPH
Benign prostatic hyperplasia which is also known as benign prostatic hypertrophy. Nonmalignant enlargement of the prostate gland.
BPPV (benign paroxysmal positional vertigo)
A balance disorder that results in the sudden onset of dizziness, spinning, or vertigo when moving the head.
Brace, foot-drop
See Ankle-foot orthosis.
Brace, Milwaukee
One of the two main types of braces used to treat the lateral curve of the spine in scoliosis. This brace can be worn to correct any curve in the spine.
Brachial artery
The artery that runs from the shoulder down to the elbow.
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This dictionary contains 19186 terms.
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