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Alternating hemiplegia of childhood
Alternating hemiplegia of childhoodA rare neurological disorder with frequent temporary episodes of paralysis of one side of the body (hemiplegia) usually beginning before the age of 18 months. The eye movements, face, or limbs can be paralysed on either side of the body, but on only one side at a time. The cause is unknown. Abbreviated AHC. Also known as alternating hemiplegia syndrome. One form of AHC has a favorable outlook. It occurs primarily at night, when a child awakens, and is apparently related to migraine. These children have no other mental or neurological impairments. Another form of AHC is more serious and may include mental impairment, balance and gait difficulties, excessive sweating, changes in body temperature, and seizures. Treatment with flunarizine , a calcium channel blocker, may help to reduce the severity and duration of attacks of paralysis. RELATED TERMS-------------------------------------- Neurological The medical science that deals with the nervous system and disorders affecting it. Paralysis Inability to move parts of the body. AHC Alternating hemiplegia of childhood. Hemiplegia Paralysis of one side of the body as a result of injury to neurons carrying signals to muscles from the motor areas of the brain. Syndrome A grouping of signs and symptoms, based on their frequent co-occurrence, that may suggest a common underlying pathogenesis, course, familial pattern, or treatment selection. Migraine A vascular headache associated with changes in the size of the arteries within and outside of the brain. A migraine begins when hyperactive nerve cells send out impulses to the blood vessels, causing constriction, followed by the dilation of these vessels and the release of prostaglandins, serotonin, and other inflammatory substances that cause the pulsation to be painful. Migraine is a genetic disorder that is inherited. A migraine causes mild to severe pain and lasts from 4 hours up to a week. Migraines usually occur 2 to 4 times per month. Impairment A defect in organ function or whole body system, which may be temporary or permanent (eg. hemiplegia). Balance A biological system that enables us to know where our bodies are in the environment and to maintain a desired position. Normal balance depends on information from the inner ear, other senses (such as sight and touch) and muscle movement. Gait Pattern of walking. Calcium Chemical element needed for healthy teeth, bones and nerves SIMILAR TERMS-------------------------------------- Alteplase Generic name of a tissue plasminogen activator produced by recombinant DNA technology. The brand name is Activase. See: Tissue plasminogen activator. Alternate hemiplegia See: Alternating hemiplegia of childhood. Alternate pathway The mechanism of complement activation that does not involve activation of the C1, C4, C2 pathway by antigen-antibody complexes, and begins with the activation of C3. Alternate Site Testing Using parts of the body other than the finger tips to obtain blood for blood glucose testing. Alternating hemiplegia syndrome See: Alternating hemiplegia of childhood. Alternative hypothesis. The opposite of a null hypothesis. See null hypothesis, research hypothesis. Alternative medical system A system of alternative medicine built upon a complete system of theory and practice. Often, such systems have evolved apart from and earlier than the conventional medical approach used in the US or Europe. Alternative medical systems may have evolved in Western or non-Western cultures. Examples of alternative medical systems that have developed in Western cultures include homeopathic medicine and naturopathic medicine. Examples of systems that have developed in non-Western cultures include traditional Chinese medicine and Ayurveda. Alternative Medicine A broad category of treatment systems (eg chiropractic, herbal medicine, acupuncture, homeopathy, naturopathy, and spiritual devotions) or culturally based healing traditions such as Chinese, Ayurvedic, and Christian Science. Alternative medicines share the common characteristic of nonacceptance by the biomedical (ie mainstream Western) establishment. Alternative medicine is also referred to as "complementary medicine." The designation "alternative medicine" is not equivalent to holistic medicine, a narrower term Alternative pathway The mechanism of complement activation that does not involve activation of the C1, C4, C2 pathway by antigen-antibody complexes, and begins with the activation of C3. Alternative splicing A mechanism by which different forms of mature mRNAs (messengers RNAs) are generated from the same gene. Alternative splicing is a regulatory mechanism by which variations in the incorporation of the exons, or coding regions, into mRNA leads to the production of more than one related protein, or isoform. PREVIOUS AND NEXT TERMS-------------------------------------- Alstrom-Hallgren syndrome See: Alstrom syndrome Alstr”m-Hallgren syndrome See: Alstrom syndrome. ALT (alanine aminotransferase) An enzyme normally present in liver and heart cells that is released into the bloodstream when the liver or heart is damaged. The blood ALT levels are elevated with liver damage (for example, from viral hepatitis) or with an insult to the heart (for example, from a heart attack). Some medications can also raise ALT levels. ALT is also called serum glutamic pyruvic transaminase (SGPT). Alteplase Generic name of a tissue plasminogen activator produced by recombinant DNA technology. The brand name is Activase. See: Tissue plasminogen activator. Alternate hemiplegia See: Alternating hemiplegia of childhood. Alternating hemiplegia of childhood Alternating hemiplegia syndrome See: Alternating hemiplegia of childhood. Alternative medical system A system of alternative medicine built upon a complete system of theory and practice. Often, such systems have evolved apart from and earlier than the conventional medical approach used in the US or Europe. Alternative medical systems may have evolved in Western or non-Western cultures. Examples of alternative medical systems that have developed in Western cultures include homeopathic medicine and naturopathic medicine. Examples of systems that have developed in non-Western cultures include traditional Chinese medicine and Ayurveda. Alternative splicing A mechanism by which different forms of mature mRNAs (messengers RNAs) are generated from the same gene. Alternative splicing is a regulatory mechanism by which variations in the incorporation of the exons, or coding regions, into mRNA leads to the production of more than one related protein, or isoform. Altitude illness "Altitude illness (or altitude sickness) is a disorder caused by being at high altitude. It commonly occurs above 8,000 feet (2,440 meters). The cause of altitude illness is a matter of oxygen physiology. At sea level the concentration of oxygen is about 21% and the barometric pressure averages 760 mmHg. As altitude increases, the concentration remains the same but the number of oxygen molecules per breath is reduced. At 12,000 feet (3,658 meters) the barometric pressure is only 483 mmHg, so there are roughly 40% fewer oxygen molecules per breath. In order to oxygenate the body effectively, your breathing rate (even while at rest) has to increase. This extra ventilation increases the oxygen content in the blood, but not to sea level concentrations. Since the amount of oxygen required for activity is the same, the body must adjust to having less oxygen. In addition, high altitude and lower air pressure cause fluid to leak from the capillaries which can cause fluid build-up in both the lungs and the brain. Continuing to higher altitudes without proper acclimatization can lead to potentially serious, even life-threatening illnesses. We thank you for using the Medical Glossary to search for Alternating hemiplegia of childhood. If you have a better definition for Alternating hemiplegia of childhood than the one presented here, please let us know by making use of the suggest a term option. This definition of Alternating hemiplegia of childhood may be disputed by other professionals. Our attempt is to provide easy definitions on Alternating hemiplegia of childhood and any other medical topic for the public at large.
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