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Allotypes
Allotypes Antigenic determinants that are present in allelic (alternate) forms. When used in association with immunoglobulin, allotypes describe allelic variants of immunoglobulins detected by antibodies raised between members of the same species.
RELATED TERMS-------------------------------------- Allelic Relating to one of a series of two or more alternate forms of a gene that occupy the same position or locus on a specific chromosome. Association 1. In dysmorphology (the study of birth defects), the nonrandom occurrence in two or more individuals of a pattern of multiple anomalies (birth defects) not known to be a malformation syndrome (such as Down syndrome), a malformation sequence (of events) or what is called a polytopic field defect (in which all of the defects are concentrated in one particular area of the body). An example of an association in dysmorphology is the VACTERL association of birth defects. 2. In genetics, the occurrence together of two or more characteristics more often than would be expected by chance alone. An example of association involves a feature on the surface of white blood cells called HLA (HLA stands for human leukocyte antigen). A particular HLA type, HLA type B-27, is associated with an increased risk for a number of diseases including ankylosing spondylitis. The extent of the association is enormous. Ankylosing spondylitis is 87 times more likely to occur in people with HLA B-27 than in the general population. Immunoglobulin A serum protein involved in immunity. An antibody. Allotypes Antigenic determinants that are present in allelic (alternate) forms. When used in association with immunoglobulin, allotypes describe allelic variants of immunoglobulins detected by antibodies raised between members of the same species. Immunoglobulins Antibodies or proteins found in blood and tissue fluids produced by cells of the immune system to bind to substances in the body that are recognized as foreign antigens. Immunoglobulins sometimes bind to antigens that are not necessarily a threat to health and provoke an allergic reaction. Antibodies Proteins produced by white blood cells. They confer immunity. SIMILAR TERMS-------------------------------------- Allodynia Pain due to a stimulus that does not normally provoke pain. Alloerotic Having to do with sexual excitement toward the same sex. The opposite is heteroerotic. Allogeneic Having a genetic dissimilarity within the same species. Allogeneic graft See: Allograft. Allogeneic transplantation To transfer a tissue or organ genetically different although belonging to or obtained from the same species. Allograft A tissue transplant (graft) between two genetically nonidentical members of a species. Allograft (allogenic graft or homograft) An organ or tissue transplanted from one individual to another of the same species, i.e. human to human. Allopath Or allopathist. A term sometimes applied to a physician who practices conventional medicine (allopathy). Allopathic Pertaining to allopathy (conventional medicine). The term was coined in 1842 by C.F.S. Hahnemann to designate the usual practice of medicine as opposed to homeopathy, the system of therapy that he founded. Allopathic medicine "The system of medical practice which treats disease by the use of remedies which produce effects different from those produced by the disease under treatment. MDs practice allopathic medicine. Also called conventional medicine. The term ""allopathy"" was coined in 1842 by C.F.S. Hahnemann to designate the usual practice of medicine (allopathy) as opposed to homeopathy, the system of therapy that he founded based on the concept that disease can be treated with drugs (in minute doses) thought capable of producing the same symptoms in healthy people as the disease itself." Allopathist See: Allopath. Allopathy "The system of medical practice which treats disease by the use of remedies which produce effects different from those produced by the disease under treatment. MDs practice allopathic medicine. The term ""allopathy"" was coined in 1842 by C.F.S. Hahnemann to designate the usual practice of medicine (allopathy) as opposed to homeopathy, the system of therapy that he founded based on the concept that disease can be treated with drugs (in minute doses) thought capable of producing the same symptoms in healthy people as the disease itself." Alloplastic Referring to adaptation by means of altering the external environment. This can be contrasted to autoplastic, which refers to the alteration of one's own behavior and responses. Allopurinol Allopurinol is a prescription or over-the-counter drug which is (or once was) legal in the United States and possibly in other countries. Active ingredient(s): allopurinol . Allopurinol sodium Allopurinol sodium is a prescription or over-the-counter drug which is (or once was) legal in the United States and possibly in other countries. Active ingredient(s): allopurinol sodium . Allosex-aviodancy a socially dictated constraint on personal disclosure to members of the other, but not one's own, sex. It affects both behavior (as in locker-room nudity, for example) and communication, as in sexual joking PREVIOUS AND NEXT TERMS-------------------------------------- Allelic Relating to one of a series of two or more alternate forms of a gene that occupy the same position or locus on a specific chromosome. Allelic exclusion The ability of heterozygous lymphoid cells to produce only one allelic form of antigen-specific receptor when they have the genetic endowment to produce both. Genes other than those for the specific receptors are usually expressed codominantly. Allergen An antigen responsible for producing allergic reactions by inducing IgE formation. Allogeneic Having a genetic dissimilarity within the same species. Allograft A tissue transplant (graft) between two genetically nonidentical members of a species. Allotypes Anaphylatoxin Substance capable of releasing histamine from mast cells. Anaphylaxis Immediate hypersensitivity response to antigenic challenge, mediated by IgE and mast cells. It is a life-threatening allergic reaction, caused by the release of pharmacologically active agents. Antigen-binding site The part of an immunoglobulin molecule that binds antigen specifically. Antigen receptor The specific antigen-binding receptor on T or B lymphocytes; these receptors are transcribed and translated from rearrangements of V genes. We thank you for using the Medical Glossary to search for Allotypes. If you have a better definition for Allotypes than the one presented here, please let us know by making use of the suggest a term option. This definition of Allotypes may be disputed by other professionals. Our attempt is to provide easy definitions on Allotypes and any other medical topic for the public at large.
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