Medical Glossary

This glossary contains:
19186
medical terms

Adenosine deaminase (ADA)




Adenosine deaminase (ADA)

An enzyme that plays a key role in salvaging purine molecules.

RELATED TERMS
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Enzyme
A cellular protein whose shape allows it to hold together several other molecules in close proximity to each other. In this way, enzymes are able to induce chemical reactions in other substances with little expenditure of energy and without being changed themselves. Basically, an enzyme acts as a catalyst.



SIMILAR TERMS
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Aden-
See: Adeno-.

Adena Regional Medical Center
The Adena Regional Medical Center is a hospital in Chillicothe, Ohio, United States.

Adenine
A purine base found in RNA and DNA; in double-stranded DNA adenine pairs with the pyrimidine thymine.

Adenine (A)
"One member of the A-T (adenine-thymine) base pair in DNA. The other base pair in DNA is G-C (guanine-cytosine). Each base pair forms a ""rung of the DNA ladder."" A DNA nucleotide is made of a molecule of sugar, a molecule of phosphoric acid, and a molecule called a base. The bases are the ""letters"" that spell out the genetic code. In DNA, the code letters are A, T, G, and C, which stand for the chemicals adenine, thymine, guanine, and cytosine, respectively. In DNA base pairing, adenine always pairs with thymine, and guanine always pairs with cytosine. Adenine is also one of the bases in RNA. There it always pairs with uracil (U). The base pairs in RNA are therefore A-U and G-C."

Adenitis
Inflammation of a gland.

Adeno-
"Prefix referring to a gland, as in adenoma and adenopathy. From the Greek aden meaning originally ""an acorn"" and later ""a gland"" in the form of an acorn. Before a vowel, adeno- becomes aden-, as in adenitis (inflammation of a gland)."

Adenocarcinoma
A cancer that develops in the lining or inner surface of an organ.

Adenocard
Adenocard is a prescription or over-the-counter drug which is (or once was) legal in the United States and possibly in other countries. Active ingredient(s): adenosine .

Adenoid cystic carcinoma
"A type of cancer that most often develops in the salivary glands of the head and neck. It may arise in other sites such as the skin, lacrimal gland, trachea, breast, cervix and prostate. Adenoid cystic carcinoma (ACC) has a characteristic appearance under the microscope. Abnormal ""nests"" or cords of certain cells (epithelial cells) can be seen to surround or infiltrate ducts and glandular structures. These structures are typically filled with a mucous-like material or contain abnormal fibrous membranes (hyaline membranes). ACC is an unusual tumor. It is slow-growing but relentless. It tends to be locally invasive and infiltrate the ""sheaths"" or coatings surrounding nerve fibers (perineural spaces). ACC often recurs years later at the site where the tumor first arose or it may metastasize. Unlike most carcinomas, it seldom metastasizes to nearby lymph nodes but rather to distant sites. The lung is the most common site of metastasis, with the liver second. Bone metastases indicate a poor prognosis . Treatment usually involves surgery to resect (remove) the tumor. Postoperative radiotherapy may help prevent local recurrence. Chemotherapy may slow the tumor but no chemotherapy has yet been found that is effective in destroying it."

Adenoidectomy
The surgical removal of the adenoids.

Adenoiditis
Infection of the adenoids.

Adenoids
Glandular tissue in the back of the throat that may swell, especially during childhood, obstruct breathing and speaking, and lead to ear infections.

Adenoids and Tonsils
"These celebrated structures in the back of the throat are composed of tissue similar to the lymph nodes or ""glands."" "

Adenoma
A benign epithelial tumor in which the cells form glandular structures or are derived from glandular epithelium.

Adenoma colon family history
See: Colon cancer family history.

Adenomatous polyposis coli
See: APC (meaning 3).

Adenomatous polyposis coli, autosomal recessive
See: MYH.

Adenomyoma
A nodule that forms around tissue of the inner uterus (endometrial tissue) as a result of adenomyosis. See adenomyosis.

Adenomyomata
Plural form of adenomyoma.

Adenomyosis
Pronounced a-den-o- mi-o-sis, this is a common benign condition of the uterus in which the endometrium (the mucous membrane lining the inside of the uterus) grows into the myometrium (the uterine musculature located just outside the endometrium). The endometrium and myometrium under normal circumstances are adjacent to one another, discrete neighbors. In adenomyosis, the endometrium boorishly implants itself in the myometrium. The myometrium may respond to this intrusion with muscular overgrowth. If an island of endometrial tissue is contained and circumscribed within the myometrium, it forms a nodule called an adenomyoma (plural: adenomyomata). Adenomyosis is made up of adeno (gland) + myo (muscle) + osis (a condition of) = a condition of glandular tissue (referring to the endometrium) in the muscle (the myometrium). Adenomyosis goes by several other names including endometriosis interna, endometriosis uterina, adenomyosis uteri and adenomyometritis.

Adenomyosis uteri
Also known more succinctly as adenomyosis (pronounced ad-den-o-mi-o- sis), this is a common benign condition of the uterus in which the endometrium (the mucous membrane lining the inside of the uterus) grows into the myometrium (the uterine musculature located just outside the endometrium) The endometrium and myometrium under normal circumstances live adjacent to one another as discrete neighbors. In adenomyosis, the endometrium invades the myometrium. The myometrium may respond to this intrusion with muscular overgrowth. If an island of endometrial tissue is contained and circumscribed within the myometrium, it forms a nodule called an adenomyoma (plural: adenomyomata). Adenomyosis is made up of adeno (gland) + myo (muscle) +osis (a condition of) = a condition of glandular tissue (referring to the endometrium) in the muscle (the myometrium). Adenomyosis goes by several other names including endometriosis interna or uterina, and adenomyometritis.

Adenopathy
"Large or ""swollen"" lymph nodes. Synonymous with lymphadenopathy."

Adenoscan
Adenoscan is a prescription or over-the-counter drug which is (or once was) legal in the United States and possibly in other countries. Active ingredient(s): adenosine .

Adenosine
A nucleoside containing adenine as its base. Adenosine acts to dilate the coronary arteries and is employed in the adenosine thallium scan of the heart.

Adenosine deaminase (ADA) deficiency
A genetic (inherited) condition that results in a immune deficiency disorder called severe combined immunodeficiency disease. Adenosine deaminase is an enzyme that plays a key role in salvaging purine molecules. ADA deficiency is of special interest in the history of genetics. The first successful instance of gene therapy in humans was carried out in 1990 by Drs. W. French Anderson, R. Michael Blaese and Kenneth W. Culver who infused genetically engineered blood cells to repair ADA deficiency.

Adenosine thallium scan
A method of examining the heart to obtain information about the blood supply to the heart muscle. Special cameras take a series of pictures of the heart. Radioactive thallium is injected into the bloodstream and serves as a tracer. The tracer attaches to certain cells and makes them visible to the special camera. The tracer attaches to the muscle cells of the heart so the imaging camera can take pictures of the heart muscles. If an area of the heart does not receive an adequate flow of blood, the cells in the underserved area do not receive as much tracer and it appears as a darker area on the picture taken by the camera.

Adenosine triphosphate
The primary fuel used by cells to generate the biochemical reactions essential for life.

Adenovirus
One of the viruses that cause the common cold.

Adensoine
Adensoine is a prescription or over-the-counter drug which is (or once was) legal in the United States and possibly in other countries. Active ingredient(s): adenosine .



PREVIOUS AND NEXT TERMS
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Adenomyomata
Plural form of adenomyoma.

Adenomyosis
Pronounced a-den-o- mi-o-sis, this is a common benign condition of the uterus in which the endometrium (the mucous membrane lining the inside of the uterus) grows into the myometrium (the uterine musculature located just outside the endometrium). The endometrium and myometrium under normal circumstances are adjacent to one another, discrete neighbors. In adenomyosis, the endometrium boorishly implants itself in the myometrium. The myometrium may respond to this intrusion with muscular overgrowth. If an island of endometrial tissue is contained and circumscribed within the myometrium, it forms a nodule called an adenomyoma (plural: adenomyomata). Adenomyosis is made up of adeno (gland) + myo (muscle) + osis (a condition of) = a condition of glandular tissue (referring to the endometrium) in the muscle (the myometrium). Adenomyosis goes by several other names including endometriosis interna, endometriosis uterina, adenomyosis uteri and adenomyometritis.

Adenomyosis uteri
Also known more succinctly as adenomyosis (pronounced ad-den-o-mi-o- sis), this is a common benign condition of the uterus in which the endometrium (the mucous membrane lining the inside of the uterus) grows into the myometrium (the uterine musculature located just outside the endometrium) The endometrium and myometrium under normal circumstances live adjacent to one another as discrete neighbors. In adenomyosis, the endometrium invades the myometrium. The myometrium may respond to this intrusion with muscular overgrowth. If an island of endometrial tissue is contained and circumscribed within the myometrium, it forms a nodule called an adenomyoma (plural: adenomyomata). Adenomyosis is made up of adeno (gland) + myo (muscle) +osis (a condition of) = a condition of glandular tissue (referring to the endometrium) in the muscle (the myometrium). Adenomyosis goes by several other names including endometriosis interna or uterina, and adenomyometritis.

Adenopathy
"Large or ""swollen"" lymph nodes. Synonymous with lymphadenopathy."

Adenosine
A nucleoside containing adenine as its base. Adenosine acts to dilate the coronary arteries and is employed in the adenosine thallium scan of the heart.

Adenosine deaminase (ADA)

Adenosine deaminase (ADA) deficiency
A genetic (inherited) condition that results in a immune deficiency disorder called severe combined immunodeficiency disease. Adenosine deaminase is an enzyme that plays a key role in salvaging purine molecules. ADA deficiency is of special interest in the history of genetics. The first successful instance of gene therapy in humans was carried out in 1990 by Drs. W. French Anderson, R. Michael Blaese and Kenneth W. Culver who infused genetically engineered blood cells to repair ADA deficiency.

Adenosine thallium scan
A method of examining the heart to obtain information about the blood supply to the heart muscle. Special cameras take a series of pictures of the heart. Radioactive thallium is injected into the bloodstream and serves as a tracer. The tracer attaches to certain cells and makes them visible to the special camera. The tracer attaches to the muscle cells of the heart so the imaging camera can take pictures of the heart muscles. If an area of the heart does not receive an adequate flow of blood, the cells in the underserved area do not receive as much tracer and it appears as a darker area on the picture taken by the camera.

Adhesive capsulitis
"Constant severe limitation of the range of motion of the shoulder due to scarring around the shoulder joint. Adhesive capsulitis is an unwanted consequence of rotator cuff disease -- damage to the rotator cuff, the set of four tendons that stabilize the shoulder joint and help move the shoulder in diverse directions. Diabetes is also a risk factor for adhesive capsulitis. The affected joint is characteristically painful and tender to palpation. Physical therapy and corticosteroid injections (a ""cortisone shot"" into the joint) are often helpful. Surgery is reserved for more advanced cases. Also called a ""frozen shoulder"" because of loss of the ability to move the shoulder in all directions."

ADI
Acceptable daily intake.

Adipocyte
A fat cell, a connective tissue cell that has differentiated and become specialized in the synthesis (manufacture) and storage of fat. The adipocyte is important to the body in maintaining proper energy balance, storing calories in the form of lipids, mobilizing energy sources in response to hormonal stimulation, and commanding changes by signal secretions. Under the microscope, the adipocyte appears bloated with triglycerides. The nucleus of the cell is displaced to one side by the fat. The cytoplasm of the cell looks like a thin line surrounding the pool of fat.

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This dictionary contains 19186 terms.







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