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| This glossary contains: 19186 medical terms |
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Acute lymphoblastic leukemia
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Acute lymphoblastic leukemia"An acute (sudden onset), rapidly progressing form of leukemia that is characterized by the presence in the blood and bone marrow of large numbers of unusually immature white blood cells destined to become lymphocytes. Acute lymphoblastic leukemia is also called acute lymphocytic leukemia and is abbreviated ALL (spoken not as the word ""all"", but as the three letters A-L-L). ALL is the most common cancer occurring in children, representing almost 25% of cancer among children. There is a sharp peak in the incidence of ALL incidence among children ages 2 to 3. This peak is approximately fourfold greater than that for infants and is nearly 10-fold greater than that for youths who are 19 years old."
RELATED TERMS--------------------------------------
Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.
Leukemia
Cancer of white blood cells. Acute leukemias are characterized by the presence of "blasts," which are immature white blood cells. Large quantities of blasts generally overgrow the bone marrow, leaving very little space for normal bone marrow cells. This type generally requires immediate treatment. Chronic leukemias are those characterized by a large and uncontrolled growth of more mature white blood cells. These types of leukemias tend not to progress as rapidly, and treatment is often milder than that of acute leukemias.
Blood
The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.
Bone
Bone refers either to a hardened connective tissue or to one of the individual structures, or organs, into which it is formed, found in many animals. Bones support body structures, protect internal organs, and (in conjunction with muscles) facilitate movement; are also involved with cell formation, calcium metabolism, and mineral storage. The bones of an animal are, collectively, known as the skeleton.
Marrow
The tissue which fills the cavities of most bones; the medulla. In the larger cavities it is commonly very fatty, but in the smaller cavities it is much less fatty, and red or reddish in color.
Cancer
Any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream.
Incidence
Statistic that equals the number of new cases of a particular disease that occur in a population during a defined period of time, usually one year.
SIMILAR TERMS--------------------------------------
Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.
Acute abdomen
The abrupt (acute) onset of abdominal pain. A potential medical emergency, an acute abdomen may reflect a major problem with one of the organs in the abdomen such as the appendix (being inflamed = appendicitis), the gallbladder (inflamed = cholecystitis), the intestine (an ulcer that has perforated), the spleen (that has ruptured), etc. The term "acute abdomen" is medical shorthand. It has nonetheless come into common usage in medical parlance.
Acute bacterial prostatitis
Inflammation of the prostate gland of sudden (acute) onset due to bacterial infection. The symptoms include chills, fever, pain in the lower back and genital area, body aches, burning or painful urination, and the frequent and urgent need to urinate. The urinary tract is infected, as evidenced by the presence of white blood cells and bacteria in the urine. Treatment is with antibiotics. The prostate, a small organ about the size of a walnut, is below the bladder (where urine is stored) and surrounds the urethra (the tube that carries urine from the bladder). The prostate normally produces a fluid that becomes part of the semen.
Acute brain syndrome
See: Delirium.
Acute confusional state
See: Delirium.
Acute coronary syndromes
A spectrum of conditions involving chest discomfort or other symptoms caused by lack of oxygen to the heart muscle (the myocardium). The unification of these manifestations of coronary artery disease under a single term reflects the understanding that these are caused by a similar pathophysiology (sequence of pathologic events) characterized by erosion, fissuring, or rupture of a pre-existing plaque, leading to thrombosis (clotting) within the coronary arteries and impaired blood supply to the heart muscle.
Acute epiglottitis
"A very rapidly progressive infection causing inflammation of the epiglottis (the flap that covers the trachea) and tissues around the epiglottis that may lead to abrupt blockage of the upper airway and death. The infection is usually caused by bacteria (such as Hemophilus influenzae, Streptococcus pneumoniae, Staphylococcus aureus, and Streptococci) and is contracted through the respiratory tract. Subsequent downward extension produces what is called cellulitis with marked inflammation of the epiglottis and nearby structures. The inflamed epiglottis mechanically obstructs the airway; the work of breathing increases, and the retention of carbon dioxide and hypoxia (low oxygen) may result. Clearance of secretions is also impaired. These factors may result in fatal asphyxia within a few hours. "
Acute fatty liver of pregnancy
Liver failure in late pregnancy, usually from unknown cause. Acute fatty liver of pregnancy (AFLP) typically occurs in first-time pregnancies in the last trimester. AFLP causes nausea and vomiting, abdominal pain especially in the upper abdomen (epigastrium), jaundice (yellowing), frequent thirst (polydipsia) and increased urination (polyuria), fatigue, headache, and altered mental state.
Acute idiopathic polyneuritis
Also known as the Guillain-Barre syndrome, a disorder characterized by progressive symmetrical paralysis and loss of reflexes, usually beginning in the leg, with in most cases nearly complete or complete recovery. The Guillain-Barre syndrome is not associated with fever. There is paralysis involving more than one limb, most commonly the legs, and that paralysis is progressive. There is areflexia (loss of reflexes) or hyporeflexia (diminution of reflexes) in the legs and arms. Other conditions that may mimic the Guillain-Barre syndrome need to be ruled out. The Guillain-Barre syndrome is due to an immune response that results in the direct destruction of the myelin sheath surrounding the peripheral nerves or the axon of the nerve itself. The syndrome sometimes follow triggering events, including vaccinations. Among the vaccines reportedly associated with Guillain-Barre syndrome are the swine influenza vaccine (in 1976-1977), the oral poliovirus vaccine, and tetanus toxoid. Aside from vaccinations, infection with the bacteria Campylobacter jejuni and viral infections can trigger the Guillain-Barre syndrome.
Acute illness
A disease with an abrupt onset and usually a short course.
Acute kidney failure
See: Acute renal failure.
Acute leukemia
Cancer of the white blood cells (leukemia) that characteristically comes on abruptly and, if not treated, progresses rapidly. The two major types of acute leukemia are acute lymphoblastic leukemia (ALL) and acute myelocytic leukemia (AML).
Acute lymphocytic leukemia
See: Acute lymphoblastic leukemia.
Acute mountain sickness (AMS)
Acute mountain sickness (AMS) is the effect on the body of being in a high altitude environment. AMS is common at high altitudes, that is above 8,000 feet (2,440 meters). Three-quarters of people have mild symptoms of AMS over 10,000 feet (3,048 meters). The occurrence of AMS depends on the altitude, the rate of ascent, and individual susceptibility.
Acute myelogenous leukemia
Abbreviated AML. Also called acute myeloid leukemia or acute nonlymphocytic leukemia (ANLL). A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children.
Acute myeloid leukemia
A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children. Acute myeloid leukemia is abbreviated AML (pronounced A M L). It is also known as acute myelogenous leukemia or acute nonlymphocytic leukemia (ANLL).
Acute myocardial infarction
This is the medical term for a heart attack. It literally means sudden death of heart muscle. This is normally caused by atherosclerosis. Also called an AMI, Coronary or MI.
Acute nonlymphocytic leukemia
Abbreviated ANLL. More commonly called acute myeloid leukemia (AML). A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children.
Acute otitis media
" Inflammation of the middle ear in which there is fluid in the middle ear accompanied by signs or symptoms of ear infection: a bulging eardrum usually accompanied by pain; or a perforated eardrum, often with drainage of purulent material (pus). Acute otitis media is the most frequent diagnosis in sick children in the U.S., especially affecting infants and preschoolers. Almost all children have one or more bouts of otitis media before age 6."
Acute pain
Pain that comes on quickly, can be severe, but lasts a relatively short time. As opposed to chronic pain.
Acute pancreatitis
Sudden inflammation of the pancreas. The pancreas abruptly becomes inflamed and then gets better. Some people have more than one attack but recover fully after each one. The cause of acute pancreatitis is most often alcohol abuse or gallstones. Other causes include use of prescribed drugs, trauma or surgery to the abdomen, or abnormalities of the pancreas or intestine. In rare cases, the disease may result from infections, such as mumps. In about 1 case in 6 or 7, the cause is unknown.
Acute phase protein
See: Acute-phase protein.
Acute phase reactant
See: Acute-phase protein.
Acute promyelocytic leukemia
"Commonly called APL, a malignancy of the bone marrow in which there is a deficiency of mature blood cells in the myeloid line of cells and an excess of immature cells called promyelocytes. APL is due to a translocation (an exchange of chromosome material) between chromosomes 15 and 17 which is symbolized t(15;17). This translocation is not a mere marker of APL. It is the cause of APL. APL was first recognized as a distinct disease entity in 1957. It accounts for 5-10% of cases of acute myeloid leukemia (AML). The peak incidence of APL is in young adults. APL is considered a type of AML and is classified as the M3 variant of AML in the internationally accepted French-American-British (FAB) Classification. "
Acute radiation syndrome
An acute illness caused by a dose greater than 50 rads of penetrating radiation to most or all of the body in a short time, usually a matter of minutes. Examples of persons who suffered from acute radiation syndrome (ARS) are the survivors of the Hiroshima and Nagasaki atomic bombs and the firefighters that first responded after the Chernobyl Nuclear Power Plant event in 1986. A person with ARS usually goes through four stages. In the prodromal stage, the classic symptoms are nausea, vomiting, and possibly diarrhea (depending on dose) that occur from minutes to days following exposure. These symptoms may last (episodically) for minutes up to several days. Then comes the latent stage. In this stage the patient looks and feels generally healthy for a few hours or even up to a few weeks. Then comes the overt or manifest illness stage, In this stage the symptoms depend on the specific ARS syndrome and last from hours up to several months. The last stage is recovery or death. Most patients who do not recover die within several months of exposure. For those who recover, the process lasts from several weeks up to two years.
Acute renal failure
Sudden and often temporary loss of kidney function. Also called acute kidney failure. As opposed to chronic renal failure.
Acute respiratory disease
A sudden condition in which breathing is difficult and the oxygen levels in the blood abruptly drop lower than normal.
Acute respiratory distress syndrome
Better known as ARDS. See: ARDS.
Acute stress disorder
The anxiety and behavioral disturbances that develop within a month of exposure to extreme trauma. The symptoms of an acute stress disorder usually begin during or shortly following the trauma. Such extreme traumatic events include rape or other severe physical assault, near-death experiences in accidents, witnessing a murder, and combat. The symptom of dissociation, which reflects a perceived detachment of the mind from the emotional state or even the body, is a critical feature. Dissociation also is characterized by a sense of the world as a dreamlike or unreal place and may be accompanied by poor memory of the specific events, which in severe form is known as dissociative amnesia. Other features of acute stress disorder include symptoms of generalized anxiety and hyperarousal, avoidance of situations or stimuli that elicit memories of the trauma, and persistent, intrusive recollections of the event via flashbacks, dreams, or recurrent thoughts or visual images. If the symptoms and behavioral disturbances of the acute stress disorder persist for more than a month, and if these features are associated with functional impairment or significant distress to the sufferer, the diagnosis is changed to posttraumatic stress disorder (PTSD).
Acute thrombocytopenic purpura
The sudden onset of low blood platelet levels with bleeding into the skin and elsewhere. Acute thrombocytopenic purpura (ATP) can be due to many causes. It may, for example, constitute a potentially serious complication during the acute phase of measles.
Acute tubular necrosis
A severe form of acute renal failure that develops in people with severe illnesses (such as sepsis) or with very low blood pressure. Patients may need dialysis. Kidney function often improves if the underlying disease is successfully treated. Abbreviated ATN.
Acute-phase protein
Any protein whose plasma concentration increases (or decreases) by 25% or more during certain inflammatory disorders. The acute-phase proteins include C-reactive protein (CRP), serum amyloid A (SAA), fibrinogen, and alpha 1-acid glycoprotein. Perhaps the best known of these acute-phase proteins is CRP, a plasma protein that rises in the blood with inflammation. The level of CRP in blood plasma can rise as high as 1000-fold with inflammation. Conditions that commonly lead to marked changes in CRP include infection, trauma, surgery, burns, inflammatory conditions, and advanced cancer. Moderate changes occur after strenuous exercise, heatstroke, and childbirth. Small changes in CRP occur after psychological stress and in several psychiatric illnesses. C-reactive protein is a test of value. Marked rises in CRP reflect the presence and intensity of inflammation. An elevation in CRP, however, is not a telltale sign pointing to just one disease. Also called an acute-phase reactant.
Acute-phase proteins
See: Acute-phase protein.
Acute-phase reactant
See: Acute-phase protein.
Acutect
Acutect is a prescription or over-the-counter drug which is (or once was) legal in the United States and possibly in other countries. Active ingredient(s): technetium tc-99m apcitide.
PREVIOUS AND NEXT TERMS--------------------------------------
Acute fatty liver of pregnancy
Liver failure in late pregnancy, usually from unknown cause. Acute fatty liver of pregnancy (AFLP) typically occurs in first-time pregnancies in the last trimester. AFLP causes nausea and vomiting, abdominal pain especially in the upper abdomen (epigastrium), jaundice (yellowing), frequent thirst (polydipsia) and increased urination (polyuria), fatigue, headache, and altered mental state.
Acute idiopathic polyneuritis
Also known as the Guillain-Barre syndrome, a disorder characterized by progressive symmetrical paralysis and loss of reflexes, usually beginning in the leg, with in most cases nearly complete or complete recovery. The Guillain-Barre syndrome is not associated with fever. There is paralysis involving more than one limb, most commonly the legs, and that paralysis is progressive. There is areflexia (loss of reflexes) or hyporeflexia (diminution of reflexes) in the legs and arms. Other conditions that may mimic the Guillain-Barre syndrome need to be ruled out. The Guillain-Barre syndrome is due to an immune response that results in the direct destruction of the myelin sheath surrounding the peripheral nerves or the axon of the nerve itself. The syndrome sometimes follow triggering events, including vaccinations. Among the vaccines reportedly associated with Guillain-Barre syndrome are the swine influenza vaccine (in 1976-1977), the oral poliovirus vaccine, and tetanus toxoid. Aside from vaccinations, infection with the bacteria Campylobacter jejuni and viral infections can trigger the Guillain-Barre syndrome.
Acute illness
A disease with an abrupt onset and usually a short course.
Acute kidney failure
See: Acute renal failure.
Acute leukemia
Cancer of the white blood cells (leukemia) that characteristically comes on abruptly and, if not treated, progresses rapidly. The two major types of acute leukemia are acute lymphoblastic leukemia (ALL) and acute myelocytic leukemia (AML).
Acute lymphoblastic leukemia
Acute lymphocytic leukemia
See: Acute lymphoblastic leukemia.
Acute mountain sickness (AMS)
Acute mountain sickness (AMS) is the effect on the body of being in a high altitude environment. AMS is common at high altitudes, that is above 8,000 feet (2,440 meters). Three-quarters of people have mild symptoms of AMS over 10,000 feet (3,048 meters). The occurrence of AMS depends on the altitude, the rate of ascent, and individual susceptibility.
Acute myelogenous leukemia
Abbreviated AML. Also called acute myeloid leukemia or acute nonlymphocytic leukemia (ANLL). A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children.
Acute myeloid leukemia
A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children. Acute myeloid leukemia is abbreviated AML (pronounced A M L). It is also known as acute myelogenous leukemia or acute nonlymphocytic leukemia (ANLL).
Acute nonlymphocytic leukemia
Abbreviated ANLL. More commonly called acute myeloid leukemia (AML). A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children.
RELATED TERMS--------------------------------------
Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.
Leukemia
Cancer of white blood cells. Acute leukemias are characterized by the presence of "blasts," which are immature white blood cells. Large quantities of blasts generally overgrow the bone marrow, leaving very little space for normal bone marrow cells. This type generally requires immediate treatment. Chronic leukemias are those characterized by a large and uncontrolled growth of more mature white blood cells. These types of leukemias tend not to progress as rapidly, and treatment is often milder than that of acute leukemias.
Blood
The life-maintaining fluid which is made up of plasma, red blood cells (erythrocytes), white blood cells (leukocytes), and platelets; blood circulates through the body's heart, arteries, veins, and capillaries; it carries away waste matter and carbon dioxide, and brings nourishment, electrolytes, hormones, vitamins, antibodies, heat, and oxygen to the tissues.
Bone
Bone refers either to a hardened connective tissue or to one of the individual structures, or organs, into which it is formed, found in many animals. Bones support body structures, protect internal organs, and (in conjunction with muscles) facilitate movement; are also involved with cell formation, calcium metabolism, and mineral storage. The bones of an animal are, collectively, known as the skeleton.
Marrow
The tissue which fills the cavities of most bones; the medulla. In the larger cavities it is commonly very fatty, but in the smaller cavities it is much less fatty, and red or reddish in color.
Cancer
Any malignant growth or tumor caused by abnormal and uncontrolled cell division; it may spread to other parts of the body through the lymphatic system or the blood stream.
Incidence
Statistic that equals the number of new cases of a particular disease that occur in a population during a defined period of time, usually one year.
SIMILAR TERMS--------------------------------------
Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.
Acute abdomen
The abrupt (acute) onset of abdominal pain. A potential medical emergency, an acute abdomen may reflect a major problem with one of the organs in the abdomen such as the appendix (being inflamed = appendicitis), the gallbladder (inflamed = cholecystitis), the intestine (an ulcer that has perforated), the spleen (that has ruptured), etc. The term "acute abdomen" is medical shorthand. It has nonetheless come into common usage in medical parlance.
Acute bacterial prostatitis
Inflammation of the prostate gland of sudden (acute) onset due to bacterial infection. The symptoms include chills, fever, pain in the lower back and genital area, body aches, burning or painful urination, and the frequent and urgent need to urinate. The urinary tract is infected, as evidenced by the presence of white blood cells and bacteria in the urine. Treatment is with antibiotics. The prostate, a small organ about the size of a walnut, is below the bladder (where urine is stored) and surrounds the urethra (the tube that carries urine from the bladder). The prostate normally produces a fluid that becomes part of the semen.
Acute brain syndrome
See: Delirium.
Acute confusional state
See: Delirium.
Acute coronary syndromes
A spectrum of conditions involving chest discomfort or other symptoms caused by lack of oxygen to the heart muscle (the myocardium). The unification of these manifestations of coronary artery disease under a single term reflects the understanding that these are caused by a similar pathophysiology (sequence of pathologic events) characterized by erosion, fissuring, or rupture of a pre-existing plaque, leading to thrombosis (clotting) within the coronary arteries and impaired blood supply to the heart muscle.
Acute epiglottitis
"A very rapidly progressive infection causing inflammation of the epiglottis (the flap that covers the trachea) and tissues around the epiglottis that may lead to abrupt blockage of the upper airway and death. The infection is usually caused by bacteria (such as Hemophilus influenzae, Streptococcus pneumoniae, Staphylococcus aureus, and Streptococci) and is contracted through the respiratory tract. Subsequent downward extension produces what is called cellulitis with marked inflammation of the epiglottis and nearby structures. The inflamed epiglottis mechanically obstructs the airway; the work of breathing increases, and the retention of carbon dioxide and hypoxia (low oxygen) may result. Clearance of secretions is also impaired. These factors may result in fatal asphyxia within a few hours. "
Acute fatty liver of pregnancy
Liver failure in late pregnancy, usually from unknown cause. Acute fatty liver of pregnancy (AFLP) typically occurs in first-time pregnancies in the last trimester. AFLP causes nausea and vomiting, abdominal pain especially in the upper abdomen (epigastrium), jaundice (yellowing), frequent thirst (polydipsia) and increased urination (polyuria), fatigue, headache, and altered mental state.
Acute idiopathic polyneuritis
Also known as the Guillain-Barre syndrome, a disorder characterized by progressive symmetrical paralysis and loss of reflexes, usually beginning in the leg, with in most cases nearly complete or complete recovery. The Guillain-Barre syndrome is not associated with fever. There is paralysis involving more than one limb, most commonly the legs, and that paralysis is progressive. There is areflexia (loss of reflexes) or hyporeflexia (diminution of reflexes) in the legs and arms. Other conditions that may mimic the Guillain-Barre syndrome need to be ruled out. The Guillain-Barre syndrome is due to an immune response that results in the direct destruction of the myelin sheath surrounding the peripheral nerves or the axon of the nerve itself. The syndrome sometimes follow triggering events, including vaccinations. Among the vaccines reportedly associated with Guillain-Barre syndrome are the swine influenza vaccine (in 1976-1977), the oral poliovirus vaccine, and tetanus toxoid. Aside from vaccinations, infection with the bacteria Campylobacter jejuni and viral infections can trigger the Guillain-Barre syndrome.
Acute illness
A disease with an abrupt onset and usually a short course.
Acute kidney failure
See: Acute renal failure.
Acute leukemia
Cancer of the white blood cells (leukemia) that characteristically comes on abruptly and, if not treated, progresses rapidly. The two major types of acute leukemia are acute lymphoblastic leukemia (ALL) and acute myelocytic leukemia (AML).
Acute lymphocytic leukemia
See: Acute lymphoblastic leukemia.
Acute mountain sickness (AMS)
Acute mountain sickness (AMS) is the effect on the body of being in a high altitude environment. AMS is common at high altitudes, that is above 8,000 feet (2,440 meters). Three-quarters of people have mild symptoms of AMS over 10,000 feet (3,048 meters). The occurrence of AMS depends on the altitude, the rate of ascent, and individual susceptibility.
Acute myelogenous leukemia
Abbreviated AML. Also called acute myeloid leukemia or acute nonlymphocytic leukemia (ANLL). A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children.
Acute myeloid leukemia
A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children. Acute myeloid leukemia is abbreviated AML (pronounced A M L). It is also known as acute myelogenous leukemia or acute nonlymphocytic leukemia (ANLL).
Acute myocardial infarction
This is the medical term for a heart attack. It literally means sudden death of heart muscle. This is normally caused by atherosclerosis. Also called an AMI, Coronary or MI.
Acute nonlymphocytic leukemia
Abbreviated ANLL. More commonly called acute myeloid leukemia (AML). A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children.
Acute otitis media
" Inflammation of the middle ear in which there is fluid in the middle ear accompanied by signs or symptoms of ear infection: a bulging eardrum usually accompanied by pain; or a perforated eardrum, often with drainage of purulent material (pus). Acute otitis media is the most frequent diagnosis in sick children in the U.S., especially affecting infants and preschoolers. Almost all children have one or more bouts of otitis media before age 6."
Acute pain
Pain that comes on quickly, can be severe, but lasts a relatively short time. As opposed to chronic pain.
Acute pancreatitis
Sudden inflammation of the pancreas. The pancreas abruptly becomes inflamed and then gets better. Some people have more than one attack but recover fully after each one. The cause of acute pancreatitis is most often alcohol abuse or gallstones. Other causes include use of prescribed drugs, trauma or surgery to the abdomen, or abnormalities of the pancreas or intestine. In rare cases, the disease may result from infections, such as mumps. In about 1 case in 6 or 7, the cause is unknown.
Acute phase protein
See: Acute-phase protein.
Acute phase reactant
See: Acute-phase protein.
Acute promyelocytic leukemia
"Commonly called APL, a malignancy of the bone marrow in which there is a deficiency of mature blood cells in the myeloid line of cells and an excess of immature cells called promyelocytes. APL is due to a translocation (an exchange of chromosome material) between chromosomes 15 and 17 which is symbolized t(15;17). This translocation is not a mere marker of APL. It is the cause of APL. APL was first recognized as a distinct disease entity in 1957. It accounts for 5-10% of cases of acute myeloid leukemia (AML). The peak incidence of APL is in young adults. APL is considered a type of AML and is classified as the M3 variant of AML in the internationally accepted French-American-British (FAB) Classification. "
Acute radiation syndrome
An acute illness caused by a dose greater than 50 rads of penetrating radiation to most or all of the body in a short time, usually a matter of minutes. Examples of persons who suffered from acute radiation syndrome (ARS) are the survivors of the Hiroshima and Nagasaki atomic bombs and the firefighters that first responded after the Chernobyl Nuclear Power Plant event in 1986. A person with ARS usually goes through four stages. In the prodromal stage, the classic symptoms are nausea, vomiting, and possibly diarrhea (depending on dose) that occur from minutes to days following exposure. These symptoms may last (episodically) for minutes up to several days. Then comes the latent stage. In this stage the patient looks and feels generally healthy for a few hours or even up to a few weeks. Then comes the overt or manifest illness stage, In this stage the symptoms depend on the specific ARS syndrome and last from hours up to several months. The last stage is recovery or death. Most patients who do not recover die within several months of exposure. For those who recover, the process lasts from several weeks up to two years.
Acute renal failure
Sudden and often temporary loss of kidney function. Also called acute kidney failure. As opposed to chronic renal failure.
Acute respiratory disease
A sudden condition in which breathing is difficult and the oxygen levels in the blood abruptly drop lower than normal.
Acute respiratory distress syndrome
Better known as ARDS. See: ARDS.
Acute stress disorder
The anxiety and behavioral disturbances that develop within a month of exposure to extreme trauma. The symptoms of an acute stress disorder usually begin during or shortly following the trauma. Such extreme traumatic events include rape or other severe physical assault, near-death experiences in accidents, witnessing a murder, and combat. The symptom of dissociation, which reflects a perceived detachment of the mind from the emotional state or even the body, is a critical feature. Dissociation also is characterized by a sense of the world as a dreamlike or unreal place and may be accompanied by poor memory of the specific events, which in severe form is known as dissociative amnesia. Other features of acute stress disorder include symptoms of generalized anxiety and hyperarousal, avoidance of situations or stimuli that elicit memories of the trauma, and persistent, intrusive recollections of the event via flashbacks, dreams, or recurrent thoughts or visual images. If the symptoms and behavioral disturbances of the acute stress disorder persist for more than a month, and if these features are associated with functional impairment or significant distress to the sufferer, the diagnosis is changed to posttraumatic stress disorder (PTSD).
Acute thrombocytopenic purpura
The sudden onset of low blood platelet levels with bleeding into the skin and elsewhere. Acute thrombocytopenic purpura (ATP) can be due to many causes. It may, for example, constitute a potentially serious complication during the acute phase of measles.
Acute tubular necrosis
A severe form of acute renal failure that develops in people with severe illnesses (such as sepsis) or with very low blood pressure. Patients may need dialysis. Kidney function often improves if the underlying disease is successfully treated. Abbreviated ATN.
Acute-phase protein
Any protein whose plasma concentration increases (or decreases) by 25% or more during certain inflammatory disorders. The acute-phase proteins include C-reactive protein (CRP), serum amyloid A (SAA), fibrinogen, and alpha 1-acid glycoprotein. Perhaps the best known of these acute-phase proteins is CRP, a plasma protein that rises in the blood with inflammation. The level of CRP in blood plasma can rise as high as 1000-fold with inflammation. Conditions that commonly lead to marked changes in CRP include infection, trauma, surgery, burns, inflammatory conditions, and advanced cancer. Moderate changes occur after strenuous exercise, heatstroke, and childbirth. Small changes in CRP occur after psychological stress and in several psychiatric illnesses. C-reactive protein is a test of value. Marked rises in CRP reflect the presence and intensity of inflammation. An elevation in CRP, however, is not a telltale sign pointing to just one disease. Also called an acute-phase reactant.
Acute-phase proteins
See: Acute-phase protein.
Acute-phase reactant
See: Acute-phase protein.
Acutect
Acutect is a prescription or over-the-counter drug which is (or once was) legal in the United States and possibly in other countries. Active ingredient(s): technetium tc-99m apcitide.
PREVIOUS AND NEXT TERMS--------------------------------------
Acute fatty liver of pregnancy
Liver failure in late pregnancy, usually from unknown cause. Acute fatty liver of pregnancy (AFLP) typically occurs in first-time pregnancies in the last trimester. AFLP causes nausea and vomiting, abdominal pain especially in the upper abdomen (epigastrium), jaundice (yellowing), frequent thirst (polydipsia) and increased urination (polyuria), fatigue, headache, and altered mental state.
Acute idiopathic polyneuritis
Also known as the Guillain-Barre syndrome, a disorder characterized by progressive symmetrical paralysis and loss of reflexes, usually beginning in the leg, with in most cases nearly complete or complete recovery. The Guillain-Barre syndrome is not associated with fever. There is paralysis involving more than one limb, most commonly the legs, and that paralysis is progressive. There is areflexia (loss of reflexes) or hyporeflexia (diminution of reflexes) in the legs and arms. Other conditions that may mimic the Guillain-Barre syndrome need to be ruled out. The Guillain-Barre syndrome is due to an immune response that results in the direct destruction of the myelin sheath surrounding the peripheral nerves or the axon of the nerve itself. The syndrome sometimes follow triggering events, including vaccinations. Among the vaccines reportedly associated with Guillain-Barre syndrome are the swine influenza vaccine (in 1976-1977), the oral poliovirus vaccine, and tetanus toxoid. Aside from vaccinations, infection with the bacteria Campylobacter jejuni and viral infections can trigger the Guillain-Barre syndrome.
Acute illness
A disease with an abrupt onset and usually a short course.
Acute kidney failure
See: Acute renal failure.
Acute leukemia
Cancer of the white blood cells (leukemia) that characteristically comes on abruptly and, if not treated, progresses rapidly. The two major types of acute leukemia are acute lymphoblastic leukemia (ALL) and acute myelocytic leukemia (AML).
Acute lymphoblastic leukemia
Acute lymphocytic leukemia
See: Acute lymphoblastic leukemia.
Acute mountain sickness (AMS)
Acute mountain sickness (AMS) is the effect on the body of being in a high altitude environment. AMS is common at high altitudes, that is above 8,000 feet (2,440 meters). Three-quarters of people have mild symptoms of AMS over 10,000 feet (3,048 meters). The occurrence of AMS depends on the altitude, the rate of ascent, and individual susceptibility.
Acute myelogenous leukemia
Abbreviated AML. Also called acute myeloid leukemia or acute nonlymphocytic leukemia (ANLL). A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children.
Acute myeloid leukemia
A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children. Acute myeloid leukemia is abbreviated AML (pronounced A M L). It is also known as acute myelogenous leukemia or acute nonlymphocytic leukemia (ANLL).
Acute nonlymphocytic leukemia
Abbreviated ANLL. More commonly called acute myeloid leukemia (AML). A quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children.
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