Medical Glossary

This glossary contains:
19186
medical terms

AML1




AML1

Acute myeloid leukemia 1 gene. See: Runx-1.

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Acute
1. Of short course. 2. Severe, but of a short duration. Not chronic.

Leukemia
Cancer of white blood cells. Acute leukemias are characterized by the presence of "blasts," which are immature white blood cells. Large quantities of blasts generally overgrow the bone marrow, leaving very little space for normal bone marrow cells. This type generally requires immediate treatment. Chronic leukemias are those characterized by a large and uncontrolled growth of more mature white blood cells. These types of leukemias tend not to progress as rapidly, and treatment is often milder than that of acute leukemias.

Gene
1. A unit of DNA that carries information for the biosynthesis of a specific product in the cell. 2. Ultimate unit by which inheritable characteristics are transmitted to succeeding generations in all living organisms. Genes are contained by, and arranged along the length of, the chromosome. The gene is composed of deoxyribonucleic acid (DNA). Each chromosome of each species has a definite number and arrangement of genes, which govern both the structure and metabolic functions of the cells and thus of the entire organism.



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Amino acid, essential
An amino acid that cannot be made by humans and so is essential to the human diet. There are 9 essential amino acids: histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, and valine.

Amino acid, nonessential
An amino acid that can be made by humans and so is not essential to the human diet. There are 11 nonessential amino acids: alanine, arginine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, proline, serine, and tyrosine.

Amino acids
The building blocks of polypeptides and proteins.

Aminotransferase
An enzyme that catalyzes the transfer of an amino group from a donor molecule to a recipient molecule. The donor molecule is usually an amino acid while the recipient (acceptor) molecule is usually an alpha-2 keto acid. An aminotransferase is also called a transaminase. Two of the better known enzymes in this class are serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase (SGPT). Both of these transaminases (SGOT and SGPT) are normally found primarily in cells in the liver and heart, are released into the bloodstream as the result of liver or heart damage, and so are used as liver and heart tests.

AML
Acute myeloid leukemia (also known as acute myelogenous leukemia), a quickly progressive malignant disease in which there are too many immature blood-forming cells in the blood and bone marrow, the cells being specifically those destined to give rise to the granulocytes or monocytes, both types of white blood cells that fight infections. In AML, these blasts do not mature and so become too numerous. AML can occur in adults or children. Acute myeloid leukemia is also known as acute myelogenous leukemia or acute nonlymphocytic leukemia (ANLL).

AML1

Ammonia
colorless gas with a very sharp odor. Made both by humans and by nature, ammonia dissolves easily in water and evaporates quickly. Liquid ammonia is found in many household cleaners. Ammonia is irritating to the skin, eyes, nose, throat, and lungs. Exposure to high concentrations in the air can severely burn the skin, eyes, throat, or lungs. In extreme cases, blindness, lung damage, or death can occur. Breathing lower concentrations causes coughing and nose and throat irritation. Swallowing ammonia may burn the mouth, throat, and stomach. The amount of ammonia produced by humans every year is almost equal to that produced by nature every year. Ammonia is produced naturally in soil by bacteria, decaying plants and animals, and animal wastes. Ammonia is essential for many biological processes. Most of the ammonia produced in chemical factories is used to make fertilizers. The remaining is used in textiles, plastics, explosives, pulp and paper production, food and beverages, household cleaning products, refrigerants, and other products. It is also used in smelling salts.

Ammonium perchlorate
See: Perchlorate.

Amnesia, antegrade
See: Antegrade amnesia.

Amnesia, anterograde
See: Antegrade amnesia.

Amnesia, retrograde
See: Retrograde amnesia.

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This dictionary contains 19186 terms.







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